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1Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
2Department of Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Copyright © 2015 Korean Endocrine Society
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
CONFLICTS OF INTEREST: No potential conflict of interest relevant to this article was reported.
We started methimazole (MMI) 30 mg/day and propranolol 30 mg/day as initial dose (month 1). Because laboratory data and symptoms suggested the disease was getting worse, doses of MMI and propranolol were gradually increased up to 45 and 120 mg/day, respectively, till 5th month. Subsequently, AST/ALT levels were increased from 28/31 to 60/81 IU/L. After one month treatment, AST/ALT levels were more increased up to 58/101 IU/L so MMI was changed to propylthiouracil 300 mg/day. However, there was no improvement in thyrotoxicosis.
T3, triiodothyronine; FT4, free thyroxine; TSH, thyroid stimulating hormone; TRAb, TSH receptor antibody; NA, not available; AST, aspartate aminotransferase; ALT, alanine aminotransferase.