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Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Copyright © 2019 Korean Endocrine Society
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
CONFLICTS OF INTEREST: No potential conflict of interest relevant to this article was reported.
GREAT, Graves' Recurrent Events After Therapy; FT4, free thyroxine; TBII, thyrotropin binding inhibitory immunoglobulin.
aWorld Health Organization grade 0=thyroid not or distinctly palpable; grade I=thyroid easily palpable and visible with head in normal or raised position; grade II=thyroid easily visible with head in normal position; grade III=goitre visible at a distance.
UK 1977 [48] | USA 1979 [49] | Japan 1986 [50] | Combined [484950] | |
---|---|---|---|---|
In remission for | 7.6±0.6 yr | 20–27 yr | >10 yr | About 20 yr |
ΔTSH-TRH ↓ (subclinical hyperthyroidism) | 17 (16) | 0 | 10 (23) | 27 (16) |
ΔTSH-TRH N (euthyroid) | 65 (59) | 9 (60) | 28 (62) | 102 (60) |
ΔTSH-TRH ↑ (subclinical hypothyroidism) | 21 (19) | 5 (33) | 5 (11) | 31 (18) |
Hypothyroid | 7 (6) | 1 (7) | 2 (4) | 10 (6) |
Total | 110 | 15 | 45 | 170 (100) |