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1Department of Internal Medicine, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Korea.
2Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Copyright © 2019 Korean Endocrine Society
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
CONFLICTS OF INTEREST: No potential conflict of interest relevant to this article was reported.
Study | Country | Population | No. | Specimen | BPA concentration, ng/mL | Thyroid measures | Association |
---|---|---|---|---|---|---|---|
Meeker et al. (2011) [5] | USA | Aged ≥20 yr | 1,346 | Urine | GM 2.5 (95% CI, 2.3–2.7) | Total/free T4, total/ free T3, TSH | Total T4↓ |
Park et al. (2017) [6] | Korea | Aged ≥20 yr | 6,003 | Urine | GM 1.13 (95% CI, 1.06–1.20) | Total T4, total T3, TSH | TSH↓ |
Sriphrapradang et al. (2013) [7] | Thailand | Aged 18–94 yr | 2,340 | Serum | Median 0.33 (min 0–max 66.91) | Free T4, TSH | Free T4↓ (men) |
Wang et al. (2013) [8] | China | Aged ≥40 yr | 3,394 | Urine | Median 0.81 (IQR, 0.47–1.43) | Free T4, free T3, TSH | Free T3↑ TSH↓ |
Andrianou et al. (2016) [9] | Cyprus, Romania | Adult women | 212 | Urine | Median 2.258 (IQR, 1,100–4,611) | Free T4, TSH, thyroid nodules | TSH↑, thyroid nodule↓ |
Geens et al. (2015) [10] | Belgium | Case-control (obese and lean) | 194 | Urine | Median 1.7 | Free T4, TSH | TSH↑ (lean) |
Meeker et al. (2010) [11] | USA | Men (infertility clinic) | 167 | Urine | Median 1.3 (IQR, 0.7–2.4) | Free T4, total T3, TSH | TSH↑ |
Zhou et al. (2017) [55] | China | Case-control | 178 | Urine | Median 4.18 (IQR, 1.74–7.01) | Thyroid cancer, nodular goiter | Thyroid cancer↑, nodular goiter↑ |
Li et al. (2019) [56] | China | Case-control, women ≥18 yr | 1,416 | Urine | Median 1.35 (IQR, 0.83–2.34) | Thyroid nodule | Thyroid nodule↑ |
Study | Country | No. (newborn) | BPA specimen | BPA concentration | Thyroid specimen | Thyroid measures | Association |
---|---|---|---|---|---|---|---|
Chevrier et al. (2013) [16] | USA | 364 | Maternal urine in the first and second half of pregnancy | GM 1.3 μg/g Cr | Blood spots after birth | TSH | TSH↓ (boys) |
Romano et al. (2015) [17] | USA | 249 | Maternal urine at 26 weeks of gestation | GM 2.3 μg/g Cr (95% CI, 2.1–2.5) | Cord blood | Total/free T4, total/free T3, TSH | TSH↓ (girls) |
Minatoya et al. (2017) [19] | Japan | 283 | Cord blood | GM 0.051 ng/mL (IQR, <LOD–0.076) | Cord blood | Free T4, TSH | None |
Sanlidag et al. (2018) [20] | Cyprus | 88 | Cord blood | Mean 4.934 ng/mL | Cord blood | Free T4, TSH | None |
Brucker-Davis et al. (2011) [21] | France | 84 | Cord blood | Median 0.9 ng/mL | (IQR, 0.2–3.3) Cord blood | Free T4, free T3, TSH | None |