Skip Navigation
Skip to contents

Endocrinol Metab : Endocrinology and Metabolism

clarivate
OPEN ACCESS
SEARCH
Search

Previous issues

Page Path
HOME > BROWSE ARTICLES > Previous issues
15 Previous issues
Filter
Filter
Article type
Keywords
Authors
Volume 27(2); June 2012
Prev issue Next issue
Review Article
AMP-activated protein kinase Activating Agent and Its Implication.
Hyoung Chul Choi
Endocrinol Metab. 2012;27(2):109-115.   Published online June 20, 2012
DOI: https://doi.org/10.3803/EnM.2012.27.2.109
  • 2,172 View
  • 32 Download
  • 3 Crossref
AbstractAbstract PDF
AMP-activated protein kinase (AMPK) is an important cellular fuel sensor. Activation of AMPK requires phosphorylation at threonine (Thr)-172, which resides in the activation loop of the alpha1 and alpha2 subunits. Several AMPK upstream kinases are capable of phosphorylating AMPK at Thr-172, including LKB1 and CaMKKbeta. AMPK has been implicated in the regulation of physiological signals, such as inhibition of cholesterol, fatty acid, protein synthesis, and enhancement of glucose uptake and blood flow. AMPK activation also exhibits several salutary effects on vascular function and improves vascular abnormalities. AMPK is activated by numerous drugs and xenobiotics. Some of these are in clinical use for the treatment of type 2 diabetes (e.g., metformin and thiazolidinediones), hypertension (e.g., nifedipine and losartan), and impaired blood flow (e.g., aspirin, statins, and cilostazol). Plant-derived xenobiotics or nutraceuticals that were claimed to have health benefits in diabetes or cancer have been reported to activate AMPK. These include resveratrol from red wine, epigallocatechin gallate from green tea, capsaicin from peppers, berberine, which is a yellow dye of the genus berberis, genistein from soy bean, and ginsenoside from ginseng panax. AMPK is also modulated by numerous hormones and cytokines that regulate energy balance at the whole body level, including leptin, adiponectin, ghrelin, and even thyroid hormones. This work shows that the precise mechanisms of AMPK kinase and AMPK interaction.

Citations

Citations to this article as recorded by  
  • Recent advances in potential of Fisetin in the management of myocardial ischemia-reperfusion injury–A systematic review
    Priyanka N. Prem, Bhavana Sivakumar, Sri Rahavi Boovarahan, Gino A. Kurian
    Phytomedicine.2022; 101: 154123.     CrossRef
  • The effects of Allomyrina dichotoma larval extract on palmitate-induced insulin resistance in skeletal muscle cells
    Kyong Kim, Mi-Seong Sim, Min-Kyu Kwak, Se-Eun Jang, Yoon Sin Oh
    Journal of Nutrition and Health.2022; 55(4): 462.     CrossRef
  • Anti-obesity Effects of Water and Ethanol Extracts of Black Ginseng
    Hye-Jin Park, Ae-Jung Kim, Yong-Pil Cheon, Myoungsook Lee
    Journal of the Korean Society of Food Science and Nutrition.2015; 44(3): 314.     CrossRef
Close layer
Editorial
Characterization of Incidentally Detected Adrenal Pheochromocytoma.
Soon Jib Yoo, Woohyeon Kim
Endocrinol Metab. 2012;27(2):116-118.   Published online June 20, 2012
DOI: https://doi.org/10.3803/EnM.2012.27.2.116
  • 1,653 View
  • 20 Download
AbstractAbstract PDF
No abstract available.
Close layer
Case Report
A Case of Asymptomatic Giant Cystic Pheochromocytoma.
Sang Hoon Lee, Seungkoo Lee, Sang Wook Kim, Eun Hee Cho
Endocrinol Metab. 2012;27(2):119-120.   Published online June 20, 2012
DOI: https://doi.org/10.3803/EnM.2012.27.2.119
  • 19,081 View
  • 21 Download
AbstractAbstract PDF
No abstract available.
Close layer
Original Articles
Differential Diagnostic Value of Total T3/Free T4 Ratio in Graves' Disease and Painless Thyroiditis Presenting Thyrotoxicosis.
Sang Min Lee, Soo Kyoung Kim, Jong Ryeal Hahm, Jung Hwa Jung, Ho Su Kim, Sungsu Kim, Soon Il Chung, Bong Hoi Choi, Tae Sik Jung
Endocrinol Metab. 2012;27(2):121-125.   Published online June 20, 2012
DOI: https://doi.org/10.3803/EnM.2012.27.2.121
  • 10,359 View
  • 68 Download
  • 3 Crossref
AbstractAbstract PDF
BACKGROUND
It is important to differentiate Graves' disease from that of painless thyroiditis in patients with thyrotoxicosis. In this study, we evaluated the usefulness of total T3 to free T4 ratio in making a differential diagnosis between Graves' disease and painless thyroiditis. METHODS: We reviewed medical records of thyrotoxic patients, who had been diagnosed with Graves' disease or painless thyroiditis, from October 2009 to July 2011. We assessed clinical characteristics, serum levels of total T3, free T4, thyroid stimulating hormone, thyrotropin-binding inhibitory immunoglobulin, and findings of 99mTechnetium thyroid scan. We analyzed the total T3/free T4 ratios between Graves' disease and painless thyroiditis patients. RESULTS: A total of 76 untreated thyrotoxic patients "49 Graves' disease and 27 painless thyroiditis" were examined. The total T3, free T4 levels and the total T3/free T4 ratios were significantly higher in patients with Graves' disease than in those with painless thyroiditis (P < 0.001). In the total T3/free T4 ratio > 73, the possibility of Graves' disease was significantly higher than in painless thyroiditis (sensitivity, 75.5%; specificity, 70.3%). The sensitivity and specificity of the total T3/free T4 ratio in patients with free T4 < 3.6 ng/dL have been increased (sensitivity, 100%; specificity, 71.4%). CONCLUSION: The total T3/free T4 ratios was useful for making a differential diagnosis between Graves' disease and painless thyroiditis.

Citations

Citations to this article as recorded by  
  • Comparison of 99mTc Pertechnetate Thyroid Uptake Rates by Gamma Probe and Gamma Camera Methods for Differentiating Graves’ Disease and Thyroiditis
    Meihua Jin, Jonghwa Ahn, Seong-gil Jo, Jangwon Park, Min Ji Jeon, Won Gu Kim, Tae Yong Kim, Won Bae Kim, Young Kee Shong, Jin-Sook Ryu
    Nuclear Medicine and Molecular Imaging.2022; 56(1): 42.     CrossRef
  • Interpretation of puzzling thyroid function tests
    Jee Hee Yoon, Ho-Cheol Kang
    Journal of the Korean Medical Association.2018; 61(4): 241.     CrossRef
  • The High Proportion of Painless Thyroiditis as a Cause of Thyrotoxicosis in Korea
    Sang Il Mo, A Jeong Ryu, Yeo Joo Kim, Sang Jin Kim
    Journal of Korean Thyroid Association.2015; 8(1): 61.     CrossRef
Close layer
The Association between Low Serum Bilirubin and Carotid Atherosclerosis in Subjects with Type 2 Diabetes.
Byoung Hyun Park, Hye Jung Nho, Chung Gu Cho
Endocrinol Metab. 2012;27(2):126-131.   Published online June 20, 2012
DOI: https://doi.org/10.3803/EnM.2012.27.2.126
  • 13,859 View
  • 22 Download
  • 3 Crossref
AbstractAbstract PDF
BACKGROUND
Bilirubin prevents oxidative modification of low density lipoprotein, and may protect vessels from atherosclerosis. Several studies showed an inverse relationship between serum bilirubin and coronary artery disease. However, there are some needs to clarify the relationship between serum bilirubin and carotid atherosclerosis in type 2 diabetes, especially. METHODS: A total of 346 type 2 diabetic patients, between 35 and 95 years of age (146 men and 200 women), were studied. Subjects with normal serum total bilirubin were divided into two groups, according to their serum total bilirubin levels (group I, total bilirubin > or = 1.0 mg/dL [n = 59]; group II, total bilirubin < or = 0.5 mg/dL [n = 76]). Carotid intima-media thickness (IMT) and plaque scores were measured by ultrasonography. Carotid atherosclerosis was defined by the presence of plaque or more than 1 mm of common carotid IMT. RESULTS: Carotid IMT was positively correlated with age, duration of diabetes and hypertension, high sensitive C-reactive protein (hs-CRP) and fibrinogen, but, it was negatively correlated with bilirubin, gamma glutaryltransferase, albumin, hemoglobin, cystatin C and estimated-glomerular filtration rate (GFR) in all subjects. After controlling for sex, age and levels of hemoglobin, direct bilirubin only was negatively correlated with carotid IMT (r = -0.151, P = 0.034). Low serum total bilirubin group had a lot of female, long duration of diabetes and hypertension, higher hs-CRP, platelet counts, serum creatinine, HbA1c and homeostasis model assessment-insulin resistance, lower albumin, hemoglobin, estimated-GFR and quantitative insulin sensitivity check index. Carotid IMT and plaque scores were significantly greater in low serum bilirubin group (0.785 +/- 0.210 mm vs. 0.678 +/- 0.146 mm, P < 0.01; 1.95 +/- 2.56 vs. 1.03 +/- 1.40, P < 0.05, respectively) than in the high serum bilirubin group. Multivariate logistic regression analysis showed that age, serum albumin and total bilirubin were independent associated factors for carotid atherosclerosis in type 2 diabetic women. CONCLUSION: Total bilirubin is inversely correlated with carotid atherosclerosis in type 2 diabetic patients, and it is an independent associated factor for carotid atherosclerosis in women.

Citations

Citations to this article as recorded by  
  • Circulating bilirubin and defense against kidney disease and cardiovascular mortality: mechanisms contributing to protection in clinical investigations
    Ai-Ching Boon, Andrew C. Bulmer, Jeff S. Coombes, Robert G. Fassett
    American Journal of Physiology-Renal Physiology.2014; 307(2): F123.     CrossRef
  • Mildly Elevated Serum Bilirubin Levels Are Negatively Associated with Carotid Atherosclerosis among Elderly Persons
    Ryuichi Kawamoto, Daisuke Ninomiya, Yoichi Hasegawa, Yoshihisa Kasai, Tomo Kusunoki, Nobuyuki Ohtsuka, Teru Kumagi, Masanori Abe, Jozef Dulak
    PLoS ONE.2014; 9(12): e114281.     CrossRef
  • Association between Total Bilirubin and Hemoglobin A1c in Korean Type 2 Diabetic Patients
    Seong-Woo Choi, Young-Hoon Lee, Sun-Seog Kweon, Hye-rim Song, Hye-Ran Ahn, Jung-Ae Rhee, Jin-Su Choi, Min-Ho Shin
    Journal of Korean Medical Science.2012; 27(10): 1196.     CrossRef
Close layer
Characterization of Incidentally Detected Adrenal Pheochromocytoma.
Ye An Kim, Yul Hwangbo, Min Joo Kim, Hyung Jin Choi, Je Hyun Seo, Yenna Lee, Soo Heun Kwak, Eu Jeong Ku, Tae Jung Oh, Eun Roh, Jae Hyun Bae, Jung Hee Kim, Kyoung Soo Park, Seong Yeon Kim
Endocrinol Metab. 2012;27(2):132-137.   Published online June 20, 2012
DOI: https://doi.org/10.3803/EnM.2012.27.2.132
  • 2,442 View
  • 30 Download
  • 3 Crossref
AbstractAbstract PDF
BACKGROUND
In approach to an adrenal incidentaloma, early exclusion of pheochromocytoma is clinically important, due to the risk of catecholamine crisis. The aims of this study are to investigate the characteristics of incidentally detected pheochromocytomas, compared with that of the other adrenal incidentalomas, and to compare these characteristics with those of symptomatic pheochromocytomas. METHODS: In this retrospective study, we reviewed the medical records of 198 patients with adrenal incidentaloma from 2001 to 2010. We analyzed the clinical, laboratory and radiological data of pheochromocytomas, in comparison with those of the other adrenal incidentalomas. We also compared the characteristics of these incidentally detected pheochromocytomas with the medical records of 28 pathologically proven pheochromocytomas, diagnosed based on typical symptoms. RESULTS: Among the 198 patients with adrenal incidentaloma, nineteen patients were diagnosed with pheochromocytoma. Pheochromocytomas showed larger size and higher Hounsfield unit at precontrast computed tomography (CT) than did non-pheochromocytomas. All pheochromocytomas were larger than 2.0 cm, and the Hounsfield units were 19 or higher in precontrast CT. When both criteria of size > 2.0 cm and Hounsfield unit > 19 were met, the sensitivity and specificity for the diagnosis of pheochromocytoma were 100% and 79.3%, respectively. Compared with patients with pheochromocytoma, diagnosed based on typical symptoms, patients with incidentally detected pheochromocytoma were older, presented less often with hypertension, and showed lower levels of 24-hour urine metanephrine. CONCLUSION: Adrenal incidentaloma with < 2.0 cm in size or < or = 19 Hounsfield units in precontrast CT imaging was less likely to be a pheochromocytoma. Patients with incidentally discovered pheochromocytoma showed lower catecholamine metabolites, compared with those patients with symptomatic pheochromocytoma.

Citations

Citations to this article as recorded by  
  • Guidelines for the Management of Adrenal Incidentaloma: the Korean Endocrine Society, Committee of Clinical Practice Guidelines
    Jung-Min Lee, Mee Kyoung Kim, Seung-Hyun Ko, Jung-Min Koh, Bo-Yeon Kim, Sang-Wan Kim, Soo-Kyung Kim, Hae-Jin Kim, Ohk-Hyun Ryu, Juri Park, Jung-Soo Lim, Seong Yeon Kim, Young Kee Shong, Soon Jib Yoo
    The Korean Journal of Medicine.2017; 92(1): 4.     CrossRef
  • Clinical Guidelines for the Management of Adrenal Incidentaloma
    Jung-Min Lee, Mee Kyoung Kim, Seung-Hyun Ko, Jung-Min Koh, Bo-Yeon Kim, Sang Wan Kim, Soo-Kyung Kim, Hae Jin Kim, Ohk-Hyun Ryu, Juri Park, Jung Soo Lim, Seong Yeon Kim, Young Kee Shong, Soon Jib Yoo
    Endocrinology and Metabolism.2017; 32(2): 200.     CrossRef
  • Characterization of Incidentally Detected Adrenal Pheochromocytoma
    Soon Jib Yoo, Woohyeon Kim
    Endocrinology and Metabolism.2012; 27(2): 116.     CrossRef
Close layer
Case Reports
Langerhans Cell Histiocytosis in the Thyroid and Draining Lymph Nodes: A Case Report.
Dong Hae Chung, Seung Yeon Ha, Hyun Yee Cho, Na Rae Kim, Jung Suk An, Young Don Lee, Sanghui Park
Endocrinol Metab. 2012;27(2):138-141.   Published online June 20, 2012
DOI: https://doi.org/10.3803/EnM.2012.27.2.138
  • 2,140 View
  • 57 Download
  • 5 Crossref
AbstractAbstract PDF
A 53-year-old woman was presented with several 0.3-0.6 cm-sized nodules within the right lobe of the thyroid. Histologic sections of the thyroid demonstrated multiple papillary microcarcinomas in the background of lymphocytic thyroiditis, with a small focus of Langerhans cell histiocytosis (LCH). Small LCH nodules were also found in the draining cervical lymph nodes. Although the association of LCH with papillary thyroid carcinoma in the thyroid has been reported, their co-existence with LCH in the draining lymph nodes is very rare.

Citations

Citations to this article as recorded by  
  • Thyroid Langerhans cell histiocytosis concurrent with papillary thyroid carcinoma: A case report and literature review
    Bin Mi, Di Wu, Yue Fan, Benjamin Ka Seng Thong, Yudong Chen, Xue Wang, Chaofu Wang
    Frontiers in Medicine.2023;[Epub]     CrossRef
  • Adult Langerhans cell histiocytosis of skull in a patient with synchronous papillary thyroid carcinoma and Castleman disease
    In Kyeong Kim, Kyoung Yul Lee
    BMJ Case Reports.2021; 14(1): e239341.     CrossRef
  • Langerhans cell histiocytosis of the thyroid together with papillary thyroid carcinoma
    Hatice Ozisik, Banu Sarer Yurekli, Derya Demir, Yesim Ertan, Ilgın Yildirim Simsir, Murat Ozdemir, Mehmet Erdogan, Sevki Cetinkalp, Gokhan Ozgen, Fusun Saygili
    Hormones.2020; 19(2): 253.     CrossRef
  • BRAF gene mutations in synchronous papillary thyroid carcinoma and Langerhans cell histiocytosis co-existing in the thyroid gland: a case report and literature review
    Mohammad A. Al Hamad, Hassan M. Albisher, Weam R. Al Saeed, Ahmed T. Almumtin, Fatimah M. Allabbad, Mohammed A. Shawarby
    BMC Cancer.2019;[Epub]     CrossRef
  • Adult Multisystem Langerhans Cell Histiocytosis Presenting with Central Diabetes Insipidus Successfully Treated with Chemotherapy
    Jung-Eun Choi, Hae Ri Lee, Jung Hun Ohn, Min Kyong Moon, Juri Park, Seong Jin Lee, Moon-Gi Choi, Hyung Joon Yoo, Jung Han Kim, Eun-Gyoung Hong
    Endocrinology and Metabolism.2014; 29(3): 394.     CrossRef
Close layer
A Case of Graves' Disease Presented as Generalized Seizure Attack.
So Young Park, Su Kyoung Park, Sung Hwan Suh, Duk Kyu Kim, Sang Ho Kim, Mi Kyoung Park, Song Yee Han, Seung Hee Ryu, Su Mi Woo, Sung Woo Lee, Neul Bom Yoon
Endocrinol Metab. 2012;27(2):142-146.   Published online June 20, 2012
DOI: https://doi.org/10.3803/EnM.2012.27.2.142
  • 23,737 View
  • 42 Download
AbstractAbstract PDF
Hyperthyroidism is diagnosed when a patient is presented with typical symptoms, such as weight loss, palpitation, and hand tremor. However, early diagnosis is difficult in elders, because they have no typical symptoms, but only cardiovascular or muscular symptoms. In hyperthyroidism, there are often with neurologic changes, leading to various neurologic symptoms. Generalized or focal seizures are rarely reported in thyrotoxicosis and thyrotoxic crisis. Further, cases of hyperthyroidism presented as generalized seizure attack are extremely rare. We report a case of hyperthyroidism. A patient is presented at the hospital with mental change, as well as generalized seizure, who was finally diagnosed to have Graves' disease. A 56-year-old male was admitted to the hospital because of mental change with generalized seizure attack. Initial neurologic evaluations, including a brain magnetic resonance imaging and electroencephalogram proved to be normal. But, thyroid function test showed abnormal results. We diagnosed him as Graves' disease and prescribed anti-thyroid drug. Thereafter, there has been no recurrence of neurologic symptoms for 12 months.
Close layer
A Case of Painless Thyroiditis Followed by Graves' Disease.
Gyeong Jae Na, Ji Hyun Kim, Se Yoon Park, Ki Won Kim, Hee Ja Ko, Sung Wan Jeon, Yeo Joo Kim, Sang Jin Kim
Endocrinol Metab. 2012;27(2):147-150.   Published online June 20, 2012
DOI: https://doi.org/10.3803/EnM.2012.27.2.147
  • 2,333 View
  • 38 Download
  • 1 Crossref
AbstractAbstract PDF
A 30-year-old man was admitted to our hospital because of fatigue, palpitation and severe weakness of both legs. The admission laboratory findings revealed thyrotoxicosis, and 131I thyroid scintigraphic imaging revealed a low radioactive iodine uptake. He was treated for painless thyroiditis for about 4 months. However, thyrotoxic state had continued and radioactive iodine uptake was markedly increased in the follow up scan. Painless thyroiditis often relapses, but rarely develops into Graves' disease. This is a rare case in which painless thyroiditis was followed by Graves' disease.

Citations

Citations to this article as recorded by  
  • A Case of Severe Recurrent Painless Thyroiditis Requiring Thyroidectomy
    So Hyun Park, Il Seong Nam-Goong, Young Il Kim, Yun Sun Kim, Yung Min Kim, Eun Sook Kim
    Journal of Korean Thyroid Association.2015; 8(1): 113.     CrossRef
Close layer
A Case of CATCH22 Syndrome with Normal Parathyroid Function.
Min Jeong Lee, So Yeon An, Chang Bum Bae, Young Bae Sohn, Yoon Sok Chung
Endocrinol Metab. 2012;27(2):151-154.   Published online June 20, 2012
DOI: https://doi.org/10.3803/EnM.2012.27.2.151
  • 1,829 View
  • 19 Download
  • 1 Crossref
AbstractAbstract PDF
CATCH 22 is a medical acronym for cardiac defects, abnormal faces, thymic hypoplasia, cleft palate, and hypocalcemia, and a variable deletion on chromosome 22. It includes DiGeorge syndrome, conotruncal anomaly face syndrome, and velo-cardio-facial syndrome. It has a prevalence estimated at 1:3,000-1:6,000. Most deletions occur at de novo, but autosomal dominant inheritance is observed in 6-10% of cases. Hormonal disorders are common in patients with CATCH22 syndrome. While hypoparathyroidism was the predominant endocrine disturbance that has been documented in the DiGeorge syndrome, other hormonal defects, such as growth hormone deficiency, hypothyroidism, and hyperthyroidism have been occurred in patients with CATCH22 syndrome. The spectrum of parathyroid gland dysfunction in this syndrome ranges from severe neonatal hypocalcemia to normal parathyroid function. Most patients are usually diagnosed in young age, but a few patients with mild abnormality are presented later in life. We report a case of CATCH22 syndrome with normal parathyroid hormone and calcium level in an adult. The diagnosis of CATCH22 syndrome was confirmed by fluorescence in situ hybridization analysis.

Citations

Citations to this article as recorded by  
  • A Case of CATCH22 Syndrome Diagnosed in Postmenopausal Woman
    Seung Kyung Lee, Min Jeong Lee, Hyo Jin Lee, Bu Kyung Kim, Young Bae Sohn, Yoon-Sok Chung
    Journal of Bone Metabolism.2013; 20(1): 57.     CrossRef
Close layer
Visual Seizure: A Reversible Complication of Non-Ketotic Hyperglycemia.
Na Young Kim, Min Su Park
Endocrinol Metab. 2012;27(2):155-158.   Published online June 20, 2012
DOI: https://doi.org/10.3803/EnM.2012.27.2.155
  • 18,877 View
  • 23 Download
AbstractAbstract PDF
A 65-year-old man with diabetes mellitus was presented with left visual aura, followed by a versive seizure, each lasting approximately 3 minutes. Neurological examination showed an intermittent left homonymous hemianopsia. Brain magnetic resonance imaging (MRI) showed right occipital lobe lesion, with cytotoxic edema. Blood glucose was 593 mg/dL and serum osmolarity was 309 mOsm/kg. The seizures were controlled by normalization of blood sugar and short-term anticonvulsant, and the lesions were resolved in a follow-up MRI. We report a case of visual seizures associated with non-ketotic hyperglycemia.
Close layer
A Case of Dopamine-Secreting Pheochromocytoma.
Jung Kyu Park, Hoon Kyu Oh, Moo Hyun Shon, Hyun Hee Kim, Eon Ju Jeon, Eui Dal Jung
Endocrinol Metab. 2012;27(2):159-162.   Published online June 20, 2012
DOI: https://doi.org/10.3803/EnM.2012.27.2.159
  • 65,995 View
  • 36 Download
  • 1 Crossref
AbstractAbstract PDF
A pheochromocytoma is a neuroectodermal tumor that originates from the chromaffin cells of the sympathetic system. It has typical symptoms or signs, such as periodic attacks of paroxysmal hypertension, palpitation, headache, and sweating, related to an increased catecholamine secretion. Types of catecholamine secreted from tumors are usually norepinephrine and epinerphrine. There are a few reports of dopamine-secreting pheochromocytoma with absence of other catecholamines secretion. Here, we report the case of a 59-year-old man with dopamine-secreting pheochromocytoma, with no typical symptoms or signs.

Citations

Citations to this article as recorded by  
  • Metanephrine negative pheochromocytoma: a rare case report of dopamine-secreting tumor in an adolescent neurofibromatosis type 1 patient
    Mi-Seon Lee, Rosie Lee, Sook-Hyun Park, Soon Hak Kwon, Jin-Young Park, Sang-Woo Lee, So-Mi Lee, Jung-Eun Moon
    Annals of Pediatric Endocrinology & Metabolism.2023; 28(4): 302.     CrossRef
Close layer
A Case of Parathyroid Apoplexy of Primary Hyperparathyroidism Presenting as Auditory Hallucinations Accompanied with Hypocalcemia.
Eon Ju Jeon, Ji Yun Jeong, Jung Guk Kim
Endocrinol Metab. 2012;27(2):163-168.   Published online June 20, 2012
DOI: https://doi.org/10.3803/EnM.2012.27.2.163
  • 22,468 View
  • 24 Download
AbstractAbstract PDF
The natural history of primary hyperparathyroidism, due to parathyroid adenoma, is unknown. Furthermore, spontaneous resolution of parathyroid necrosis or hemorrhage is rare and usually asymptomatic. Here, we report a case of parathyroid apoplexy of primary hyperparathyroidism, presenting as auditory hallucinations, accompanied with hypocalcemia. A 39-year-old man who was incidentally diagnosed with primary hyperparathyroidism, and waiting surgery for parathyroidectomy presented to psychiatric service with auditory hallucinations. He developed tetany, while taking psychiatric drugs. On a follow-up investigation, his serum calcium level fell from 11.8 to 5.8 mg/dL. His intact parathyroid hormone level also decreased from 1,017 pg/mL to 71.1 pg/mL. The parathyroid apoplexy was confirmed after a surgical removal of the infarcted adenoma. The auditory hallucinations disappeared, and serum calcium level was returned to within the normal range.
Close layer
Letter
Letter: Increased Carotid Intima-Media Thickness Is Associated with Progression of Diabetic Nephropathy in Patients with Type 2 Diabetes.
Sang Soo Kim
Endocrinol Metab. 2012;27(2):169-170.   Published online June 20, 2012
DOI: https://doi.org/10.3803/EnM.2012.27.2.169
  • 1,518 View
  • 18 Download
AbstractAbstract PDF
No abstract available.
Close layer
Comment
Response: Increased Carotid Intima-Media Thickness Is Associated with Progression of Diabetic Nephropathy in Patients with Type 2 Diabetes.
Dong Hyeok Cho
Endocrinol Metab. 2012;27(2):171-172.   Published online June 20, 2012
DOI: https://doi.org/10.3803/EnM.2012.27.2.171
  • 66,013 View
  • 21 Download
  • 1 Crossref
AbstractAbstract PDF
No abstract available.

Citations

Citations to this article as recorded by  
  • Morphological Carotid Plaque Area Is Associated With Glomerular Filtration Rate: A Study of South Asian Indian Patients With Diabetes and Chronic Kidney Disease
    Anudeep Puvvula, Ankush D. Jamthikar, Deep Gupta, Narendra N. Khanna, Michele Porcu, Luca Saba, Klaudija Viskovic, Janet N. A. Ajuluchukwu, Ajay Gupta, Sophie Mavrogeni, Monika Turk, John R. Laird, Gyan Pareek, Martin Miner, Petros P. Sfikakis, Athanasios
    Angiology.2020; 71(6): 520.     CrossRef
Close layer

Endocrinol Metab : Endocrinology and Metabolism