Diabetes is one of the foremost public health issues worldwide that can lead to complications in many organ systems, and has become a significant cause of morbidity and mortality in Korea. According to data from the National Health Insurance Service (NHIS), about 2.7 million Koreans (8.0%) aged 30 years or older had type 2 diabetes mellitus (T2DM) in 2013. The prevalence of T2DM increased with age and rose from 5.6% in 2006 to 8.0% in 2013. Using data based on The Health Screening Service of the NHIS, 25% of Korean adults were reported to have prediabetes in 2013. The prevalence of an impaired fasting glucose tended to increase over time from 21.5% in 2006 to 25.0% in 2013. Even though nationwide health screening has been regularly conducted as a public service, the proportion of undiagnosed cases of diabetes was still reported to be on the higher side in the latest study. Based on the results of these epidemic studies, further actions will be needed to effectively implement lifestyle changes on a social level and increase measures for the early detection of diabetes to stem the tide of the epidemic.

Citations

Citations to this article as recorded by  

• A Nationwide Population‐Based Study for the Recurrence and Comorbidities in Sudden Sensorineural Hearing Loss
  Hye Yeon Ko, Hae Jeong Nam, Min Hee Kim
  The Laryngoscope.2024; 134(3): 1417.     CrossRef
• Real-World Outcomes of Individualized Targeted Therapy with Insulin Glargine 300 Units/mL in Insulin-Naïve Korean People with Type 2 Diabetes: TOBE Study
  Eun-Gyoung Hong, Kyung-Wan Min, Jung Soo Lim, Kyu-Jeung Ahn, Chul Woo Ahn, Jae-Myung Yu, Hye Soon Kim, Hyun Jin Kim, Won Kim, Dong Han Kim, Hak Chul Jang
  Advances in Therapy.2024;[Epub]     CrossRef
• Cancer risk according to fasting blood glucose trajectories: a population-based cohort study
  Thi Minh Thu Khong, Thi Tra Bui, Hee-Yeon Kang, Jinhee Lee, Eunjung Park, Jin-Kyoung Oh
  BMJ Open Diabetes Research & Care.2024; 12(1): e003696.     CrossRef
• Nomenclature Dilemma of Metabolic Associated Fatty Liver Disease (MAFLD): Considerable Proportions of MAFLD Are Metabolic Healthy
  Huiyul Park, Eileen L. Yoon, Mimi Kim, Seon Cho, Eun-Hee Nah, Dae Won Jun
  Clinical Gastroenterology and Hepatology.2023; 21(4): 1041.     CrossRef
• Efficacy of Polydeoxyribonucleotide in Promoting the Healing of Diabetic Wounds in a Murine Model of Streptozotocin-Induced Diabetes: A Pilot Experiment
  Jiyoung Yun, SaeGwang Park, Ha Young Park, Kyung Ah Lee
  International Journal of Molecular Sciences.2023; 24(3): 1932.     CrossRef
• Influence of Fasting Glucose Level on Gastric Cancer Incidence in a Prospective Cohort Study
  Tao Thi Tran, Jeonghee Lee, Madhawa Gunathilake, Hyunsoon Cho, Jeongseon Kim
  Cancer Epidemiology, Biomarkers & Prevention.2022; 31(1): 254.     CrossRef
• A Comparative analysis of type 2 diabetes management quality indicators in cancer survivors
  Eun J. Ko, Su J. Lee
  Asia-Pacific Journal of Oncology Nursing.2022; 9(11): 100116.     CrossRef
• Comparative Effects of Sodium-Glucose Cotransporter 2 Inhibitor and Thiazolidinedione Treatment on Risk of Stroke among Patients with Type 2 Diabetes Mellitus
  Seung Eun Lee, Hyewon Nam, Han Seok Choi, Hoseob Kim, Dae-Sung Kyoung, Kyoung-Ah Kim
  Diabetes & Metabolism Journal.2022; 46(4): 567.     CrossRef
• Prevalence and diagnosis experience of osteoporosis in postmenopausal women over 50: Focusing on socioeconomic factors
  Min Hyeok Choi, Ji Hee Yang, Jae Seung Seo, Yoon-ji Kim, Suk-Woong Kang, Jose M. Moran
  PLOS ONE.2021; 16(3): e0248020.     CrossRef
• Effect of Teneligliptin versus Sulfonylurea on Major Adverse Cardiovascular Outcomes in People with Type 2 Diabetes Mellitus: A Real-World Study in Korea
  Da Hea Seo, Kyoung Hwa Ha, So Hun Kim, Dae Jung Kim
  Endocrinology and Metabolism.2021; 36(1): 70.     CrossRef
• A nationwide study of patients with monoclonal gammopathy of undetermined significance with a 10-year follow-up in South Korea
  Ka-Won Kang, Ji Eun Song, Byung-Hyun Lee, Min Ji Jeon, Eun Sang Yu, Dae Sik Kim, Se Ryeon Lee, Hwa Jung Sung, Chul Won Choi, Yong Park, Byung Soo Kim
  Scientific Reports.2021;[Epub]     CrossRef
• Fibrosis Burden of Missed and Added Populations According to the New Definition of Metabolic Dysfunction-Associated Fatty Liver
  Huiyul Park, Eileen L. Yoon, Mimi Kim, Jung-Hwan Kim, Seon Cho, Dae Won Jun, Eun-Hee Nah
  Journal of Clinical Medicine.2021; 10(19): 4625.     CrossRef
• The Effects of Glucose Lowering Agents on the Secondary Prevention of Coronary Artery Disease in Patients with Type 2 Diabetes
  Inha Jung, Hyemi Kwon, Se Eun Park, Kyung-Do Han, Yong-Gyu Park, Eun-Jung Rhee, Won-Young Lee
  Endocrinology and Metabolism.2021; 36(5): 977.     CrossRef
• Decreased Vagal Activity and Deviation in Sympathetic Activity Precedes Development of Diabetes
  Da Young Lee, Mi Yeon Lee, Jung Hwan Cho, Hyemi Kwon, Eun-Jung Rhee, Cheol-Young Park, Ki-Won Oh, Won-Young Lee, Sung-Woo Park, Seungho Ryu, Se Eun Park
  Diabetes Care.2020; 43(6): 1336.     CrossRef
• Efficacy and safety of ertugliflozin in East/Southeast Asian patients with type 2 diabetes mellitus
  Jie Liu, Shrita Patel, Nilo B. Cater, Larry Wu, Susan Huyck, Steven G. Terra, Anne Hickman, Amanda Darekar, Annpey Pong, Ira Gantz
  Diabetes, Obesity and Metabolism.2020; 22(4): 574.     CrossRef
• Outcomes for Inappropriate Renal Dose Adjustment of Dipeptidyl Peptidase-4 Inhibitors in Patients With Type 2 Diabetes Mellitus: Population-Based Study
  Sangmo Hong, Kyungdo Han, Cheol-Young Park
  Mayo Clinic Proceedings.2020; 95(1): 101.     CrossRef
• Longitudinal Study of Diabetic Differences between International Migrants and Natives among the Asian Population
  Heng Piao, Jae Moon Yun, Aesun Shin, Belong Cho
  Biomolecules & Therapeutics.2020; 28(1): 110.     CrossRef
• Risk of active tuberculosis development in contacts exposed to infectious tuberculosis in congregate settings in Korea
  Shin Young Park, Sunmi Han, Young-Man Kim, Jieun Kim, Sodam Lee, Jiyeon Yang, Un-Na Kim, Mi-sun Park
  Scientific Reports.2020;[Epub]     CrossRef
• The Combined Impact of Chronic Kidney Disease and Diabetes on the Risk of Colorectal Cancer Depends on Sex: A Nationwide Population-Based Study
  Hyung Jung Oh, Hye Ah Lee, Chang Mo Moon, Dong-Ryeol Ryu
  Yonsei Medical Journal.2020; 61(6): 506.     CrossRef
• Coffee Consumption, Genetic Polymorphisms, and the Risk of Type 2 Diabetes Mellitus: A Pooled Analysis of Four Prospective Cohort Studies
  An Na Kim, Hyun Jeong Cho, Jiyoung Youn, Taiyue Jin, Moonil Kang, Joohon Sung, Jung Eun Lee
  International Journal of Environmental Research and Public Health.2020; 17(15): 5379.     CrossRef
• Current findings of kidney biopsy including nephropathy associated with hypertension and diabetes mellitus in Korea
  Kipyo Kim, Sang Ho Lee, Sung Woo Lee, Jung Pyo Lee, Ho Jun Chin
  The Korean Journal of Internal Medicine.2020; 35(5): 1173.     CrossRef
• A Diabetes-Related Dietary Pattern Is Associated with Incident Diabetes in Obese Men in the Korean Genome Epidemiology Study
  Hye Ah Lee, NaYeong Son, Won Kyung Lee, Hyesook Park
  The Journal of Nutrition.2019; 149(2): 323.     CrossRef
• Associations of postmenopausal hormone therapy with metabolic syndrome among diabetic and non-diabetic women
  Ji-Eun Kim, Jaesung Choi, JooYong Park, Jong-koo Lee, Aesun Shin, Sang Min Park, Daehee Kang, Ji-Yeob Choi
  Maturitas.2019; 121: 76.     CrossRef
• The changing epidemiology of herpes zoster over a decade in South Korea, 2006–2015
  Jae-Ki Choi, Sun Hee Park, Sanghyun Park, Sung-Yeon Cho, Hyo-Jin Lee, Si-Hyun Kim, Su-Mi Choi, Dong-Gun Lee, Jung-Hyun Choi, Jin-Hong Yoo
  Vaccine.2019; 37(36): 5153.     CrossRef
• Prevalence of undiagnosed diabetes and pre-diabetes and its associated risk factors in Vietnam
  Van Dat Nguyen, Quang Mai Vien, Thai Hung Do, Cong Danh Phan, Huu Chau Nguyen, Van Tuyen Nguyen, Dinh Luong Nguyen, Won Seok Sir, Yun Chon
  Journal of Global Health Science.2019;[Epub]     CrossRef
• Heterogeneous Trajectories of Cognitive Function in Older Adults with Diabetes: Findings from the Korean Longitudinal Study of Aging (KLoSA)
  Chanhee Kim, Min Jung Kim, Chang Gi Park
  Stress.2019; 27(1): 1.     CrossRef
• The Effect of Coffee Consumption on the Prevalence of Diabetes Mellitus: The 2012–2016 Korea National Health and Nutrition Examination Survey
  Yejee Lim, Youngmi Park, Sun Kyu Choi, Soyeon Ahn, Jung Hun Ohn
  Nutrients.2019; 11(10): 2377.     CrossRef
• Effects of sodium-glucose cotransporter-2 inhibitors and dipeptidyl peptidase-4 inhibitors on diabetic retinopathy and its progression: A real-world Korean study
  Yoo-Ri Chung, Kyoung Hwa Ha, Kihwang Lee, Dae Jung Kim, Ping-Hsun Wu
  PLOS ONE.2019; 14(10): e0224549.     CrossRef
• Letter: Projection of Diabetes Prevalence in Korean Adults for the Year 2030 Using Risk Factors Identified from National Data (Diabetes Metab J 2019;43:90–6)
  Bo Kyung Koo
  Diabetes & Metabolism Journal.2019; 43(2): 242.     CrossRef
• Changes of computed tomography‐based body composition after adrenalectomy in patients with endogenous hypercortisolism
  Namki Hong, Jooyeon Lee, Cheol Ryong Ku, Kichang Han, Cho Rok Lee, Sang Wook Kang, Yumie Rhee
  Clinical Endocrinology.2019; 90(2): 267.     CrossRef
• Estimating Lifetime Duration of Diabetes by Age and Gender in the Korean Population Using a Markov Model
  Seung Woo Cho, Seon Ha Kim, Young-Eun Kim, Seok-Jun Yoon, Min-Woo Jo
  Journal of Korean Medical Science.2019;[Epub]     CrossRef
• Hospital-Based Korean Diabetes Prevention Study: A Prospective, Multi-Center, Randomized, Open-Label Controlled Study
  Sang Youl Rhee, Suk Chon, Kyu Jeung Ahn, Jeong-Taek Woo
  Diabetes & Metabolism Journal.2019; 43(1): 49.     CrossRef
• Medical Big Data Is Not Yet Available: Why We Need Realism Rather than Exaggeration
  Hun-Sung Kim, Dai-Jin Kim, Kun-Ho Yoon
  Endocrinology and Metabolism.2019; 34(4): 349.     CrossRef
• Implementation of the Chronic Disease Care System and its association with health care costs and continuity of care in Korean adults with type 2 diabetes mellitus
  Woorim Kim, Yoon Soo Choy, Sang Ah Lee, Eun-Cheol Park
  BMC Health Services Research.2018;[Epub]     CrossRef
• Trends in diabetes prevalence among Korean adults based on Korean National Health and Nutrition Examination Surveys III–VI
  Jae-woo Lee, Hee-Taik Kang, Hyoung-Ji Lim, Byoungjin Park
  Diabetes Research and Clinical Practice.2018; 138: 57.     CrossRef
• Insulin Resistance and the Risk of Diabetes and Dysglycemia in Korean General Adult Population
  Jong Ha Baek, Hosu Kim, Kyong Young Kim, Jaehoon Jung
  Diabetes & Metabolism Journal.2018; 42(4): 296.     CrossRef
• Relationship Between Circulating Netrin-1 Concentration, Impaired Fasting Glucose, and Newly Diagnosed Type 2 Diabetes
  Jisook Yim, Gyuri Kim, Byung-Wan Lee, Eun Seok Kang, Bong-Soo Cha, Jeong-Ho Kim, Jin Won Cho, Sang-Guk Lee, Yong-ho Lee
  Frontiers in Endocrinology.2018;[Epub]     CrossRef
• Serum metabolite profile associated with incident type 2 diabetes in Koreans: findings from the Korean Genome and Epidemiology Study
  Soo Jin Yang, So-Young Kwak, Garam Jo, Tae-Jin Song, Min-Jeong Shin
  Scientific Reports.2018;[Epub]     CrossRef
• Trends in the prevalence of metabolic syndrome and its components in South Korea: Findings from the Korean National Health Insurance Service Database (2009–2013)
  Seung Eun Lee, Kyungdo Han, Yu Mi Kang, Seon-Ok Kim, Yun Kyung Cho, Kyung Soo Ko, Joong-Yeol Park, Ki-Up Lee, Eun Hee Koh, Ying-Mei Feng
  PLOS ONE.2018; 13(3): e0194490.     CrossRef
• Effect of Change in Total Cholesterol Levels on Cardiovascular Disease Among Young Adults
  Su‐Min Jeong, Seulggie Choi, Kyuwoong Kim, Sung Min Kim, Gyeongsil Lee, Seong Yong Park, Yeon‐Yong Kim, Joung Sik Son, Jae‐Moon Yun, Sang Min Park
  Journal of the American Heart Association.2018;[Epub]     CrossRef
• Age, sex, and the association of chronic kidney disease with all-cause mortality in Buddhist priests
  Hyo Jin Kim, Yunmi Kim, Sejoong Kim, Ho Jun Chin, Hajeong Lee, Jung Pyo Lee, Dong Ki Kim, Kook-Hwan Oh, Kwon Wook Joo, Yon Su Kim, Deuk-Young Nah, Sung Joon Shin, Kyung Soo Kim, Jae Yoon Park, Kyung Don Yoo
  Medicine.2018; 97(45): e13099.     CrossRef
• Association of change in total cholesterol level with mortality: A population-based study
  Su-Min Jeong, Seulggie Choi, Kyuwoong Kim, Sung-Min Kim, Gyeongsil Lee, Joung Sik Son, Jae-Moon Yun, Sang Min Park, Katriina Aalto-Setala
  PLOS ONE.2018; 13(4): e0196030.     CrossRef
• High hemoglobin levels are associated with decreased risk of diabetic retinopathy in Korean type 2 diabetes
  Min-Kyung Lee, Kyung-Do Han, Jae-Hyuk Lee, Seo-Young Sohn, Jee-Sun Jeong, Mee-Kyoung Kim, Ki-Hyun Baek, Ki-Ho Song, Hyuk-Sang Kwon
  Scientific Reports.2018;[Epub]     CrossRef
• Impact of systemic inflammation on the relationship between insulin resistance and all-cause and cancer-related mortality
  Da Young Lee, Eun-Jung Rhee, Yoosoo Chang, Chong Il Sohn, Ho-Cheol Shin, Seungho Ryu, Won-Young Lee
  Metabolism.2018; 81: 52.     CrossRef
• The two isoforms of matrix metalloproteinase- 2 have distinct renal spatial and temporal distributions in murine models of types 1 and 2 diabetes mellitus
  Il Young Kim, Sang Soo Kim, Hye Won Lee, Sun Sik Bae, Hong Koo Ha, Eun Soon Jung, Min Young Lee, Miyeun Han, Harin Rhee, Eun Young Seong, Dong Won Lee, Soo Bong Lee, David H. Lovett, Sang Heon Song
  BMC Nephrology.2018;[Epub]     CrossRef
• The optimal cut-off of blood pressure related to left ventricular diastolic dysfunction and remodeling in Asian diabetic patients
  Ju Young Jung, Sung Keun Park, Jae-Hong Ryoo, Chang-Mo Oh, Jeong Gyu Kang, Kanghee Moon, Keum Ok Lee, Joong-Myung Choi
  Journal of Cardiology.2018; 71(1): 16.     CrossRef
• Articles inEndocrinology and Metabolismin 2016
  Won-Young Lee
  Endocrinology and Metabolism.2017; 32(1): 62.     CrossRef
• Factors Associated with Smoking Cessation Intention among Current Smokers with Diabetes: Analysis of the 2013 Community Health Survey in Korea
  Young-Hoon Lee, Jum Suk Ko
  Korean Journal of Health Promotion.2017; 17(3): 184.     CrossRef
• The differences in the incidence of diabetes mellitus and prediabetes according to the type of HMG-CoA reductase inhibitors prescribed in Korean patients
  Tong Min Kim, Hyunah Kim, Yoo Jin Jeong, Sun Jung Baik, So Jung Yang, Seung-Hwan Lee, Jae-Hyoung Cho, Hyunyong Lee, Hyeon Woo Yim, In Young Choi, Kun-Ho Yoon, Hun-Sung Kim
  Pharmacoepidemiology and Drug Safety.2017; 26(10): 1156.     CrossRef
• Analysis and comparison of the cost-effectiveness of statins according to the baseline low-density lipoprotein cholesterol level in Korea
  Y. J. Jeong, H. Kim, S. J. Baik, T. M. Kim, S. J. Yang, S.-H. Lee, J.-H. Cho, H. Lee, H. W. Yim, I. Y. Choi, K.-H. Yoon, H.-S. Kim
  Journal of Clinical Pharmacy and Therapeutics.2017; 42(3): 292.     CrossRef
• Associations of Dietary Antioxidants and Risk of Type 2 Diabetes: Data from the 2007–2012 Korea National Health and Nutrition Examination Survey
  Dan Quansah, Kyungho Ha, Shinyoung Jun, Seong-Ah Kim, Sangah Shin, Gyung-Ah Wie, Hyojee Joung
  Molecules.2017; 22(10): 1664.     CrossRef
• Accuracy of Capillary Blood Glucose Test When Fasting in Diabetes Patients or General Population: Performance Evaluation of G300 Based on ISO 15197:2013 Standards
  Young-min Jee, Min-hee Seo, Byung-wook Yoo, Sung-ho Hong, Choo-yon Cho, Yong-jin Cho, Jung-eun Oh, Kyung-suk Shin
  Korean Journal of Health Promotion.2017; 17(4): 259.     CrossRef
• Increased Vascular Disease Mortality Risk in Prediabetic Korean Adults Is Mainly Attributable to Ischemic Stroke
  Nam Hoon Kim, Tae Yeon Kwon, Sungwook Yu, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Yousung Park, Sin Gon Kim
  Stroke.2017; 48(4): 840.     CrossRef

It is well known that many Korean patients with type 2 diabetes mellitus (T2DM) were non-obese and had decreased insulin secretion in past. However, during the past three decades, lifestyles in Korea have been westernized. As a result, the prevalence of obesity, the main cause of diabetes has increased. Thus, there is still a question as to whether the main pathophysiology of current Korean T2DM is insulin resistance or an insulin secretion defect. Because various anti-diabetes medications having different mechanisms of action are currently used as therapeutics, it is important to understand which of these factors is the main physiology in the development of diabetes in Koreans. In this review, we review changes in obesity prevalence, insulin resistance and insulin secretion defects in Korean T2DM during three decades.

Citations

Citations to this article as recorded by  

• Association of polygenic risk scores for insulin resistance risk and their interaction with a plant-based diet, especially fruits, vitamin C, and flavonoid intake, in Asian adults
  Sunmin Park
  Nutrition.2023; 111: 112007.     CrossRef
• Triglyceride-Glucose Index Cutoff Point Is an Accurate Marker for Predicting the Prevalence of Metabolic Syndrome in Obese Caucasian Subjects
  David Primo, Olatz Izaola, Daniel A. de Luis
  Annals of Nutrition and Metabolism.2023; 79(2): 238.     CrossRef
• A double‐blind, Randomized controlled trial on glucose‐lowering EFfects and safety of adding 0.25 or 0.5 mg lobeglitazone in type 2 diabetes patients with INadequate control on metformin and dipeptidyl peptidase‐4 inhibitor therapy: REFIND study
  Soree Ryang, Sang Soo Kim, Ji Cheol Bae, Ji Min Han, Su Kyoung Kwon, Young Il Kim, Il Seong Nam‐Goong, Eun Sook Kim, Mi‐kyung Kim, Chang Won Lee, Soyeon Yoo, Gwanpyo Koh, Min Jeong Kwon, Jeong Hyun Park, In Joo Kim
  Diabetes, Obesity and Metabolism.2022; 24(9): 1800.     CrossRef
• Waist circumference, body mass index, and colorectal cancer risk according to diabetes status: A Korean nationwide population‐based cohort study
  Dae Bum Kim, Kang‐Moon Lee, Ji Min Lee, Seung‐Hyun Ko, Kyung‐Do Han, Yong Gyu Park
  Journal of Gastroenterology and Hepatology.2021; 36(2): 397.     CrossRef
• Glucose‐lowering action through targeting islet dysfunction in type 2 diabetes: Focus on dipeptidyl peptidase‐4 inhibition
  Bo Ahrén
  Journal of Diabetes Investigation.2021; 12(7): 1128.     CrossRef
• The triglyceride–glucose index is a more powerful surrogate marker for predicting the prevalence and incidence of type 2 diabetes mellitus than the homeostatic model assessment of insulin resistance
  Hye Min Park, Hye Sun Lee, Yong-Jae Lee, Jun-Hyuk Lee
  Diabetes Research and Clinical Practice.2021; 180: 109042.     CrossRef
• Efficacy and Safety of Pioglitazone versus Glimepiride after Metformin and Alogliptin Combination Therapy: A Randomized, Open-Label, Multicenter, Parallel-Controlled Study
  Jeong Mi Kim, Sang Soo Kim, Jong Ho Kim, Mi Kyung Kim, Tae Nyun Kim, Soon Hee Lee, Chang Won Lee, Ja Young Park, Eun Sook Kim, Kwang Jae Lee, Young Sik Choi, Duk Kyu Kim, In Joo Kim
  Diabetes & Metabolism Journal.2020; 44(1): 67.     CrossRef
• Effect of roux-en Y gastric bypass surgery on patients with type 2 diabetes mellitus
  Ke-Yan Chen, Ying-Li Liu, Jin-Cai Shang, De-Wang Su, Rong-Rong Yao, De-Zhi Ke, Hao Tian
  Medicine.2020; 99(23): e20382.     CrossRef
• Diabetes, microRNA, and Nutrition in Geriatrics
  Telma Angelina Faraldo Corrêa, Marcelo Macedo Rogero
  Current Geriatrics Reports.2020; 9(4): 229.     CrossRef
• High genetic risk scores of SLIT3, PLEKHA5 and PPP2R2C variants increased insulin resistance and interacted with coffee and caffeine consumption in middle-aged adults
  J.W. Daily, M. Liu, S. Park
  Nutrition, Metabolism and Cardiovascular Diseases.2019; 29(1): 79.     CrossRef
• Failure of monotherapy in clinical practice in patients with type 2 diabetes: The Korean National Diabetes Program
  Ja Young Jeon, Soo Jin Lee, Sieun Lee, Soo Jin Kim, Seung Jin Han, Hae Jin Kim, Dae Jung Kim, Young Seol Kim, Jeong Taek Woo, Kyu Jeung Ahn, Moonsuk Nam, Sei Hyun Baik, Yongsoo Park, Kwan‐Woo Lee
  Journal of Diabetes Investigation.2018; 9(5): 1144.     CrossRef
• Efficacy and tolerability of novel triple combination therapy in drug-naïve patients with type 2 diabetes from the TRIPLE-AXEL trial: protocol for an open-label randomised controlled trial
  Nam Hoon Kim, Soo Lim, Soo Heon Kwak, Min Kyong Moon, Jun Sung Moon, Yong-ho Lee, Ho Chan Cho, Juneyoung Lee, Sin Gon Kim
  BMJ Open.2018; 8(9): e022448.     CrossRef
• Impact of systemic inflammation on the relationship between insulin resistance and all-cause and cancer-related mortality
  Da Young Lee, Eun-Jung Rhee, Yoosoo Chang, Chong Il Sohn, Ho-Cheol Shin, Seungho Ryu, Won-Young Lee
  Metabolism.2018; 81: 52.     CrossRef
• Fimasartan increases glucose‐stimulated insulin secretion in patients with type 2 diabetes and hypertension compared with amlodipine
  Ye Seul Yang, Min Hyuk Lim, Seong Ok Lee, Eun Roh, Chang Ho Ahn, Soo Heon Kwak, Young Min Cho, Sungwan Kim, Andrea Mari, Kyong Soo Park, Hye Seung Jung
  Diabetes, Obesity and Metabolism.2018; 20(7): 1670.     CrossRef
• Insulin Resistance and Its Association with Metabolic Syndrome in Korean Children
  Jinkyung Cho, Haeryun Hong, Soohyun Park, Shinuk Kim, Hyunsik Kang
  BioMed Research International.2017; 2017: 1.     CrossRef
• Articles inEndocrinology and Metabolismin 2016
  Won-Young Lee
  Endocrinology and Metabolism.2017; 32(1): 62.     CrossRef

Excess energy intake, without a compensatory increase of energy expenditure, leads to obesity. Several molecules are involved in energy homeostasis regulation and new ones are being discovered constantly. Appetite regulating hormones such as ghrelin, peptide tyrosine-tyrosine and amylin or incretins such as the gastric inhibitory polypeptide have been studied extensively while other molecules such as fibroblast growth factor 21, chemerin, irisin, secreted frizzle-related protein-4, total bile acids, and heme oxygenase-1 have been linked to energy homeostasis regulation more recently and the specific role of each one of them has not been fully elucidated. This mini review focuses on the above mentioned molecules and discusses them in relation to their regulation by the macronutrient composition of the diet as well as diet-induced weight loss.

Citations

Citations to this article as recorded by  

• Extracts of Dunkelfelder Grape Seeds and Peel Increase the Metabolic Rate and Reduce Fat Deposition in Mice Maintained on a High-Fat Diet
  Chenlu Yang, Xuelin Tian, Yulei Han, Xueqing Shi, Hua Wang, Hua Li
  Foods.2023; 12(17): 3251.     CrossRef
• Insulin Resistance and Glucose Metabolism during Infection
  Borros Arneth
  Endocrines.2023; 4(4): 685.     CrossRef
• CMKLR1 senses chemerin/resolvin E1 to control adipose thermogenesis and modulate metabolic homeostasis
  Zewei Zhao, Siqi Liu, Bingxiu Qian, Lin Zhou, Jianglin Shi, Junxi Liu, Lin Xu, Zhonghan Yang
  Fundamental Research.2022;[Epub]     CrossRef
• Dissecting biological activities of fibroblast growth factor receptors by the coiled-coil-mediated oligomerization of FGF1
  Natalia Porebska, Marta Pozniak, Mateusz Adam Krzyscik, Agata Knapik, Aleksandra Czyrek, Marika Kucinska, Kamil Jastrzebski, Malgorzata Zakrzewska, Jacek Otlewski, Lukasz Opalinski
  International Journal of Biological Macromolecules.2021; 180: 470.     CrossRef
• Oral Semaglutide, the First Ingestible Glucagon-Like Peptide-1 Receptor Agonist: Could It Be a Magic Bullet for Type 2 Diabetes?
  Hwi Seung Kim, Chang Hee Jung
  International Journal of Molecular Sciences.2021; 22(18): 9936.     CrossRef
• Serum interleukin 15 in anorexia nervosa: Comparison to normal weight and obese girls
  Wojciech Roczniak, Agata Mikołajczak-Będkowska, Elżbieta Świętochowska, Zofia Ostrowska, Katarzyna Ziora, Sylwia Balcerowicz, Karolina Górska-Flak, Magdalena Milan, Joanna Oświęcimska
  The World Journal of Biological Psychiatry.2020; 21(3): 203.     CrossRef
• Physiology of energy homeostasis: Models, actors, challenges and the glucoadipostatic loop
  Didier Chapelot, Keyne Charlot
  Metabolism.2019; 92: 11.     CrossRef
• Correlates of zinc finger BED domain-containing protein 3 and ghrelin in metabolic syndrome patients with and without prediabetes
  Rawan AbuZayed, Nailya Bulatova, Violet Kasabri, Maysa Suyagh, Lana Halaseh, Sundus AlAlawi
  Hormone Molecular Biology and Clinical Investigation.2019;[Epub]     CrossRef
• Pharmacotherapy of obesity: Available medications and drugs under investigation
  Eleni Pilitsi, Olivia M. Farr, Stergios A. Polyzos, Nikolaos Perakakis, Eric Nolen-Doerr, Aimilia-Eirini Papathanasiou, Christos S. Mantzoros
  Metabolism.2019; 92: 170.     CrossRef
• Link between chemerin, central obesity, and parameters of the Metabolic Syndrome: findings from a longitudinal study in obese children participating in a lifestyle intervention
  Petra Niklowitz, Juliane Rothermel, Nina Lass, Andre Barth, Thomas Reinehr
  International Journal of Obesity.2018; 42(10): 1743.     CrossRef
• The relationship between the leptin/ghrelin ratio and meals with various macronutrient contents in men with different nutritional status: a randomized crossover study
  Edyta Adamska-Patruno, Lucyna Ostrowska, Joanna Goscik, Barbara Pietraszewska, Adam Kretowski, Maria Gorska
  Nutrition Journal.2018;[Epub]     CrossRef
• The Science of Obesity Management: An Endocrine Society Scientific Statement
  George A Bray, William E Heisel, Ashkan Afshin, Michael D Jensen, William H Dietz, Michael Long, Robert F Kushner, Stephen R Daniels, Thomas A Wadden, Adam G Tsai, Frank B Hu, John M Jakicic, Donna H Ryan, Bruce M Wolfe, Thomas H Inge
  Endocrine Reviews.2018; 39(2): 79.     CrossRef
• Articles inEndocrinology and Metabolismin 2016
  Won-Young Lee
  Endocrinology and Metabolism.2017; 32(1): 62.     CrossRef
• Weight loss technology for people with treated type 2 diabetes: a randomized controlled trial
  Kuat Oshakbayev, Bibazhar Dukenbayeva, Gulnar Togizbayeva, Aigul Durmanova, Meruyert Gazaliyeva, Abdul Sabir, Aliya Issa, Alisher Idrisov
  Nutrition & Metabolism.2017;[Epub]     CrossRef
• Salivary, gingival crevicular fluid and serum levels of ghrelin and chemerin in patients with periodontitis and overweight
  H. F. R. Jentsch, N. Arnold, V. Richter, J. Deschner, T. Kantyka, S. Eick
  Journal of Periodontal Research.2017; 52(6): 1050.     CrossRef

Increased detection of thyroid nodules using high-resolution ultrasonography has resulted in a world-wide increase in the incidence of differentiated thyroid cancer (DTC). Despite the steep increase in its incidence, the age-standardized mortality rate of thyroid cancer has remained stable, which leads toward a trend of more conservative treatment. The latest American Thyroid Association (ATA) guidelines for thyroid nodules and thyroid cancer revised in 2015 suggested that fine needle aspiration biopsy should be performed for thyroid nodules larger than 1 cm and lobectomy might be sufficient for 1 to 4 cm intrathyroidal DTC. In addition, active surveillance instead of immediate surgical treatment was also recommended as a treatment option for papillary thyroid microcarcinoma based on the results of a few observational studies from Japan. The Korean Thyroid Association (KTA) has organized a task force team to develop revised guidelines for thyroid nodules and DTC after an extensive review of articles and intense discussion on whether we should accept the changes in the 2015 ATA guidelines. This paper introduces and discusses the updated major issues and differences in the ATA and the KTA guidelines.

Citations

Citations to this article as recorded by  

• Intraoperative pathologic evaluation of central compartment lymph nodes in patients undergoing lobectomy for unilateral papillary thyroid carcinoma
  Hye Lim Bae, Jong-hyuk Ahn, JungHak Kwak, Hyun Soo Kim, Sang Gab Yoon, Jin Wook Yi, Su-jin Kim, Kyu Eun Lee
  Asian Journal of Surgery.2024; 47(1): 360.     CrossRef
• Global scientific trends on thyroid disease in early 21st century: a bibliometric and visualized analysis
  Mingyuan Song, Wei Sun, Qi Liu, Zhongqing Wang, Hao Zhang
  Frontiers in Endocrinology.2024;[Epub]     CrossRef
• A Narrative Review of the 2023 Korean Thyroid Association Management Guideline for Patients with Thyroid Nodules
  Eun Kyung Lee, Young Joo Park, Chan Kwon Jung, Dong Gyu Na
  Endocrinology and Metabolism.2024; 39(1): 61.     CrossRef
• Lowering Barriers to Health Risk Assessments in Promoting Personalized Health Management
  Hayoung Park, Se Young Jung, Min Kyu Han, Yeonhoon Jang, Yeo Rae Moon, Taewook Kim, Soo-Yong Shin, Hee Hwang
  Journal of Personalized Medicine.2024; 14(3): 316.     CrossRef
• Prognostic Utility of Tumor Stage versus American Thyroid Association Risk Class in Thyroid Cancer
  Arash Abiri, Jonathan Pang, Karthik R. Prasad, Khodayar Goshtasbi, Edward C. Kuan, William B. Armstrong, Yarah M. Haidar, Tjoson Tjoa
  The Laryngoscope.2023; 133(1): 205.     CrossRef
• Active surveillance for PTMC warranted for the UK population?
  Pavithran Maniam, Noah Harding, Lucy Li, Richard Adamson, Ashley Hay, Ian Nixon
  Clinical Otolaryngology.2023; 48(1): 88.     CrossRef
• Cost-effectiveness of active surveillance versus early surgery for thyroid micropapillary carcinoma based on diagnostic and treatment norms in China
  Min Lai, Miao Miao Zhang, Qing Qing Qin, Yu An, Yan Ting Li, Wen Zhen Yuan
  Frontiers in Endocrinology.2023;[Epub]     CrossRef
• Biopsy strategies for intermediate and high suspicion thyroid nodules with macrocalcifications
  Sungmok Kim, Jae Ho Shin, Yon Kwon Ihn
  Current Medical Research and Opinion.2023; 39(2): 179.     CrossRef
• Active surveillance versus immediate surgery: A comparison of clinical and quality of life outcomes among patients with highly suspicious thyroid nodules 1 cm or smaller in China
  Chunhao Liu, Hao Zhao, Yu Xia, Yue Cao, Liyang Zhang, Ya Zhao, Luying Gao, Ruifeng Liu, Yuewu Liu, Hongfeng Liu, Zhilan Meng, Shuzhou Liu, Ying Lu, Xiaoyi Li
  European Journal of Surgical Oncology.2023; 49(9): 106917.     CrossRef
• SThy-Net: a feature fusion-enhanced dense-branched modules network for small thyroid nodule classification from ultrasound images
  Abdulrhman H. Al-Jebrni, Saba Ghazanfar Ali, Huating Li, Xiao Lin, Ping Li, Younhyun Jung, Jinman Kim, David Dagan Feng, Bin Sheng, Lixin Jiang, Jing Du
  The Visual Computer.2023; 39(8): 3675.     CrossRef
• Response to Letter to the Editor on Surgical Outcomes in Patients With Low-Risk Papillary Thyroid Microcarcinoma From MAeSTro Study: Immediate Operation Versus Delayed Operation Following Active Surveillance: A Multicenter Prospective Cohort Study
  Hyeonuk Hwang, June Young Choi, Jae Hoon Moon, Eun Kyung Lee, Young Joo Park, Su-jin Kim, Yuh-Seog Jung
  Annals of Surgery Open.2023; 4(3): e311.     CrossRef
• The Association of Pregnancy with Disease Progression in Patients Previously Treated for Differentiated Thyroid Cancer: A Propensity Score-Matched Retrospective Cohort Study
  Xin Li, Wu-Cai Xiao, Fang Mei, Rui Shan, Shi-Bing Song, Bang-Kai Sun, He-Ling Bao, Jing Chen, Chun-Hui Yuan, Zheng Liu
  Journal of Women's Health.2023; 32(11): 1174.     CrossRef
• Mortality rate and causes of death in papillary thyroid microcarcinoma
  Jung Heo, Hyun Jin Ryu, Hyunju Park, Tae Hyuk Kim, Sun Wook Kim, Young Lyun Oh, Jae Hoon Chung
  Endocrine.2023; 83(3): 671.     CrossRef
• Surgical Outcomes in Patients With Low-risk Papillary Thyroid Microcarcinoma From MAeSTro Study
  Hyeonuk Hwang, June Young Choi, Hyeong Won Yu, Jae Hoon Moon, Ji-hoon Kim, Eun Kyung Lee, Yeo Koon Kim, Chang Yoon Lee, Sun Wook Cho, Eun-Jae Chung, Chang Hwan Ryu, Junsun Ryu, Ka Hee Yi, Do Joon Park, Kyu Eun Lee, Young Joo Park, Su-jin Kim, Yuh-Seog Jun
  Annals of Surgery.2023; 278(5): e1087.     CrossRef
• US Predictors of Papillary Thyroid Microcarcinoma Progression at Active Surveillance
  Ji Ye Lee, Ji-hoon Kim, Yeo Koon Kim, Chang Yoon Lee, Eun Kyung Lee, Jae Hoon Moon, Hoon Sung Choi, Hwangbo Yul, Sun Wook Cho, Su-jin Kim, Kyu Eun Lee, Do Joon Park, Young Joo Park
  Radiology.2023;[Epub]     CrossRef
• Bilaterality as a Risk Factor for Recurrence in Papillary Thyroid Carcinoma
  Hyeji Kim, Hyungju Kwon
  Cancers.2023; 15(22): 5414.     CrossRef
• Clinical and molecular genetic analysis of cytologically uncertain thyroid nodules in patients with thyroid disease
  Jindrich Lukas, Barbora Hintnausova, Vlasta Sykorova, Martin Syrucek, Marek Maly, David Lukas, Jaroslava Duskova
  Biomedical Papers.2023;[Epub]     CrossRef
• Thyroid Papillary Microcarcinoma - Carcinoma with Clinically Benign Behaviour
  Hitesh R Singhavi, Manish Mair, Burhanuddin Qayyumi, Arjun Singh, Pankaj Chaturvedi
  Journal of Head & Neck Physicians and Surgeons.2023; 11(2): 95.     CrossRef
• Trends in Diagnosis of Noninvasive Follicular Thyroid Neoplasm With Papillarylike Nuclear Features and Total Thyroidectomies for Patients With Papillary Thyroid Neoplasms
  Lisa Caulley, Antoine Eskander, Weining Yang, Edel Auh, Lydia Cairncross, Nancy L. Cho, Bahar Golbon, Subramania Iyer, Jeffrey C. Liu, Paul J. Lee, Brenessa Lindeman, Charles Meltzer, Nicole Molin, Alessandra Moore, Julia Noel, Halie Nozolino, Jesse Paste
  JAMA Otolaryngology–Head & Neck Surgery.2022; 148(2): 99.     CrossRef
• What's in a Name? A Cost-Effectiveness Analysis of the Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features' Nomenclature Revision
  Vikas Mehta, Ankita Naraparaju, David Liao, Louise Davies, Bryan R. Haugen, Peter A. Kopp, Susan J. Mandel, Yuri E. Nikiforov, Douglas S. Ross, Jennifer J. Shin, R. Michael Tuttle, Gregory W. Randolph
  Thyroid.2022; 32(4): 421.     CrossRef
• Clinical management of low-risk papillary thyroid microcarcinoma
  Chie MASAKI, Kiminori SUGINO, Koichi ITO
  Minerva Endocrinology.2022;[Epub]     CrossRef
• Can Active Surveillance Management be Developed for Patients With Low-Risk Papillary Thyroid Microcarcinoma? A Preliminary Investigation in a Chinese Population
  Wen Liu, Weihan Cao, Zhizhong Dong, Ruochuan Cheng
  Endocrine Practice.2022; 28(4): 391.     CrossRef
• Assessment of Radiofrequency Ablation for Papillary Microcarcinoma of the Thyroid
  Sam P. J. van Dijk, Hannelore I. Coerts, Sabrina T. G. Gunput, Evert F. S. van Velsen, Marco Medici, Adriaan Moelker, Robin P. Peeters, Cornelis Verhoef, Tessa M. van Ginhoven
  JAMA Otolaryngology–Head & Neck Surgery.2022; 148(4): 317.     CrossRef
• The Future of Thyroid Nodule Risk Stratification
  Nydia Burgos, Naykky Singh Ospina, Jennifer A. Sipos
  Endocrinology and Metabolism Clinics of North America.2022; 51(2): 305.     CrossRef
• Complication Rates of Total Thyroidectomy vs Hemithyroidectomy for Treatment of Papillary Thyroid Microcarcinoma
  Vivian Hsiao, Tyler J. Light, Abdullah A. Adil, Michael Tao, Alexander S. Chiu, Mary Hitchcock, Natalia Arroyo, Sara Fernandes-Taylor, David O. Francis
  JAMA Otolaryngology–Head & Neck Surgery.2022; 148(6): 531.     CrossRef
• Malignancy risk stratification of thyroid nodules smaller than 10 mm with ACR-TIRADS, K-TIRADS, and ATA-2015 guidelines: a prospective study
  Mehrdad Nabahati, Zoleika Moazezi
  Egyptian Journal of Radiology and Nuclear Medicine.2022;[Epub]     CrossRef
• Thyroglobulin-Based Risk Factor Repositioning for Determining Radioactive Iodine Activity in Patients with Papillary Thyroid Carcinoma: a Multicenter Retrospective Cohort Study
  Subin Jeon, Seong Young Kwon, Sang-Woo Lee, Sang Kyun Bae
  Nuclear Medicine and Molecular Imaging.2022; 56(4): 173.     CrossRef
• Quality of Life of Survivors of Thyroid Cancer Is Not Inferior to That in Subjects without Cancer: Long-Term after Over 5 Years
  Jeongmin Lee, Youn-Ju Lee, Dong-Jun Lim, Jung-Min Lee, Sang-Ah Chang, Min-Hee Kim
  Endocrinology and Metabolism.2022; 37(4): 664.     CrossRef
• Residual, regrowth, and new growth of radiofrequency ablation for benign thyroid nodules of different volumes: two-year follow-up results
  Meng-Hsiang Chen, Wei-Che Lin, Sheng-Dean Luo, Pi-Ling Chiang, Yueh-Sheng Chen, Wei-Chih Chen, An-Ni Lin, Cheng-Kang Wang, Jung-Hwan Baek, Hsiu-Ling Chen
  International Journal of Hyperthermia.2022; 39(1): 1172.     CrossRef
• Progression of Low-Risk Papillary Thyroid Microcarcinoma During Active Surveillance: Interim Analysis of a Multicenter Prospective Cohort Study of Active Surveillance on Papillary Thyroid Microcarcinoma in Korea
  Eun Kyung Lee, Jae Hoon Moon, Yul Hwangbo, Chang Hwan Ryu, Sun Wook Cho, June Young Choi, Eun-Jae Chung, Woo-Jin Jeong, Yuh-Seog Jung, Junsun Ryu, Su-jin Kim, Min Joo Kim, Yeo Koon Kim, Chang Yoon Lee, Ji Ye Lee, Hyeong Won Yu, Jeong Hun Hah, Kyu Eun Lee,
  Thyroid.2022; 32(11): 1328.     CrossRef
• Recent Changes in the Incidence of Thyroid Cancer in Korea between 2005 and 2018: Analysis of Korean National Data
  Yun Mi Choi, Jiwoo Lee, Mi Kyung Kwak, Min Ji Jeon, Tae Yong Kim, Eun-Gyoung Hong, Won Bae Kim, Won Gu Kim
  Endocrinology and Metabolism.2022; 37(5): 791.     CrossRef
• Strain Versus 2D Shear-Wave Elastography Parameters—Which Score Better in Predicting Thyroid Cancer?
  Andreea Borlea, Ioan Sporea, Alexandru Popa, Mihnea Derban, Laura Taban, Dana Stoian
  Applied Sciences.2022; 12(21): 11147.     CrossRef
• Estimating the risk of completion total thyroidectomy using real-world data to guide initial surgical decision-making for patients with clinical low-risk papillary thyroid carcinoma
  Wen Liu, Xiangxiang Zhan, Zhizhong Dong, Yanjun Su, Jianming Zhang, Jun Qian, Yunhai Ma, Chang Diao, Ruochuan Cheng
  Holistic Integrative Oncology.2022;[Epub]     CrossRef
• Rigorous radiofrequency ablation can completely treat low-risk small papillary thyroid carcinoma without affecting subsequent surgical management
  Xinyang Li, Jie Li, Zhi Qiao, Lin Yan, Jing Xiao, Yingying Li, Mingbo Zhang, Yukun Luo
  European Radiology.2022; 33(6): 4189.     CrossRef
• Whirling technique for thyroid fine needle aspiration biopsy: a preliminary study of effectiveness and safety
  Jae Ho Shin, Seung Wan Han, Hyang Lim Lee, Yon Kwon Ihn
  Ultrasonography.2021; 40(1): 147.     CrossRef
• Value of dual-phase, contrast-enhanced CT combined with ultrasound for the diagnosis of metastasis to central lymph nodes in patients with papillary thyroid cancer
  Ying Liu, Sheng Li, Cuiju Yan, Caiyun He, Miao Yun, Min Liu, Jianhua Zhou, Longzhong Liu
  Clinical Imaging.2021; 75: 5.     CrossRef
• Clinical outcomes of T4a papillary thyroid cancer with recurrent laryngeal nerve involvement: a retrospective analysis
  Han-Seul Na, Hyun-Keun Kwon, Sung-Chan Shin, Yong-Il Cheon, Myeonggu Seo, Jin-Choon Lee, Eui-Suk Sung, Minhyung Lee, In-Joo Kim, Bo Hyun Kim, Byung-Joo Lee
  Scientific Reports.2021;[Epub]     CrossRef
• Protocol for a Korean Multicenter Prospective Cohort Study of Active Surveillance or Surgery (KoMPASS) in Papillary Thyroid Microcarcinoma
  Min Ji Jeon, Yea Eun Kang, Jae Hoon Moon, Dong Jun Lim, Chang Yoon Lee, Yong Sang Lee, Sun Wook Kim, Min-Hee Kim, Bo Hyun Kim, Ho-Cheol Kang, Minho Shong, Sun Wook Cho, Won Bae Kim
  Endocrinology and Metabolism.2021; 36(2): 359.     CrossRef
• Thyroid nodules in childhood‐onset Hashimoto's thyroiditis: Frequency, risk factors, follow‐up course and genetic alterations of thyroid cancer
  Yun Jeong Lee, Yeon Jin Cho, You Joung Heo, Eun‐Jae Chung, Young Hun Choi, Jong‐Il Kim, Young Joo Park, Choong Ho Shin, Young Ah Lee
  Clinical Endocrinology.2021; 95(4): 638.     CrossRef
• Clinical implications of age and excellent response to therapy in patients with high‐risk differentiated thyroid carcinoma
  Meihua Jin, Jonghwa Ahn, Yu‐Mi Lee, Tae‐Yon Sung, Dong Eun Song, Tae Yong Kim, Ki‐Wook Chung, Jin‐Sook Ryu, Won Bae Kim, Young Kee Shong, Min Ji Jeon, Won Gu Kim
  Clinical Endocrinology.2021; 95(6): 882.     CrossRef
• Ecografía clínica de la glándula tiroides y del cuello
  Pepa Bertrán Culla, David Teixidó Gimeno, Pere Guirado Vila
  FMC - Formación Médica Continuada en Atención Primaria.2021; 28(7): 390.     CrossRef
• Active Surveillance as an Effective Management Option for Low-Risk Papillary Thyroid Microcarcinoma
  Min Ji Jeon, Won Gu Kim, Tae Yong Kim, Young Kee Shong, Won Bae Kim
  Endocrinology and Metabolism.2021; 36(4): 717.     CrossRef
• Clinical Effects of Microwave Ablation in the Treatment of Low-Risk Papillary Thyroid Microcarcinomas and Related Histopathological Changes
  Chenya Lu, Xingjia Li, Xiaoqiu Chu, Ruiping Li, Jie Li, Jianhua Wang, Yalin Wang, Yang Xu, Guofang Chen, Shuhang Xu, Chao Liu
  Frontiers in Endocrinology.2021;[Epub]     CrossRef
• Optimization of follow-up in patients with papillary thyroid cancer who show no evidence of disease 9–12 months after treatment
  Fabian Nordell, Ghadir Hallal, Pernilla Asp, Martin Almquist
  BJS Open.2021;[Epub]     CrossRef
• The most reliable time point for intact parathyroid hormone measurement to predict hypoparathyroidism after total thyroidectomy with central neck dissection to treat papillary thyroid carcinoma: a prospective cohort study
  Jae Won Chang, Ki Wan Park, Seung-Nam Jung, Lihua Liu, Sung Min Kim, Bon Seok Koo
  European Archives of Oto-Rhino-Laryngology.2020; 277(2): 549.     CrossRef
• Time Trends for Prostate Cancer Incidence from 2003 to 2013 in South Korea: An Age-Period-Cohort Analysis
  Hyun Young Lee, Do Kyoung Kim, Seung Whan Doo, Won Jae Yang, Yun Seob Song, Bora Lee, Jae Heon Kim
  Cancer Research and Treatment.2020; 52(1): 301.     CrossRef
• Clinical behavior and outcome of papillary T1 thyroid cancers: South Korea vs. Turkey vs. Colombia in a cohort study analyzing oncological outcomes
  Murat Ozdemir, Yong-Sang Lee, Ozer Makay, Juan Pablo Dueñas, Bulent Yazici, Aysegul Akgun, Gokhan Icoz, Mahir Akyildiz, Soo Young Kim, Seok-Mo Kim, Hojin Chang, Hang-Seok Chang, Cheong Soo Park
  Asian Journal of Surgery.2020; 43(8): 795.     CrossRef
• Radioiodine ablation in thyroid cancer patients: renal function and external radiation dose rate at discharge according to patient preparation
  Yeon-Hee Han, Hwan-Jeong Jeong, Myung-Hee Sohn, Sun Y. Lee, Seok T. Lim
  The Quarterly Journal of Nuclear Medicine and Molecular Imaging.2020;[Epub]     CrossRef
• Effect of the location and size of thyroid nodules on the diagnostic performance of ultrasound elastography: A retrospective analysis
  Xinxin Xie, Yongqiang Yu
  Clinics.2020; 75: e1720.     CrossRef

• Fine-Needle Aspiration of Subcentimeter Thyroid Nodules in the Real-World Management

  
  Chaiho Jeong, Hyunsam Kim, Jeongmin Lee, Jeonghoon Ha, Min-Hee Kim, Moo Il Kang, Dong-Jun Lim
  Cancer Management and Research.2020; Volume 12: 7611.     CrossRef
• Continuing controversy regarding individualized surgical decision-making for patients with 1–4 cm low-risk differentiated thyroid carcinoma: A systematic review
  Wen Liu, Xuejing Yan, Ruochuan Cheng
  European Journal of Surgical Oncology.2020; 46(12): 2174.     CrossRef
• Clinical Implication of World Health Organization Classification in Patients with Follicular Thyroid Carcinoma in South Korea: A Multicenter Cohort Study
  Meihua Jin, Eun Sook Kim, Bo Hyun Kim, Hee Kyung Kim, Hyon-Seung Yi, Min Ji Jeon, Tae Yong Kim, Ho-Cheol Kang, Won Bae Kim, Young Kee Shong, Mijin Kim, Won Gu Kim
  Endocrinology and Metabolism.2020; 35(3): 618.     CrossRef
• Clinical Outcomes of N1b Papillary Thyroid Cancer Patients Treated with Two Different Doses of Radioiodine Ablation Therapy
  Meihua Jin, Jonghwa Ahn, Yu-Mi Lee, Tae-Yon Sung, Won Gu Kim, Tae Yong Kim, Jin-Sook Ryu, Won Bae Kim, Young Kee Shong, Min Ji Jeon
  Endocrinology and Metabolism.2020; 35(3): 602.     CrossRef
• A Propensity Score‐matched Comparison Study of Surgical Outcomes in Patients with Differentiated Thyroid Cancer After Robotic Versus Open Total Thyroidectomy
  Dong Sik Bae, Do Hoon Koo
  World Journal of Surgery.2019; 43(2): 540.     CrossRef
• Diagnostic value of cytology, thyroglobulin, and combination of them in fine-needle aspiration of metastatic lymph nodes in patients with differentiated thyroid cancer
  Yixin Xu, Dapeng Wu, Wenting Wu, Jian Jiang, Cheng Xi, Nianyuan Ye, Yibo Wang, Xuezhong Xu
  Medicine.2019; 98(45): e17859.     CrossRef
• Investigation of blood groups in benign thyroid diseases in Turkey
  Murat Dağdeviren, İhsan Ateş, Burak Furkan Demir, Emine Ergün, Canan Yıldız, Mustafa Altay
  Endocrine Journal.2019; 66(11): 1001.     CrossRef
• Tumor Volume Doubling Time in Active Surveillance of Papillary Thyroid Carcinoma
  Hye-Seon Oh, Hyemi Kwon, Eyun Song, Min Ji Jeon, Tae Yong Kim, Jeong Hyun Lee, Won Bae Kim, Young Kee Shong, Ki-Wook Chung, Jung Hwan Baek, Won Gu Kim
  Thyroid.2019; 29(5): 642.     CrossRef
• Tumor doubling time predicts response to sorafenib in radioactive iodine-refractory differentiated thyroid cancer
  Min Joo Kim, Seok-Mo Kim, Eun Kyung Lee, Yul Hwangbo, You Jin Lee, Sun Wook Cho, Do Joon Park, Yumi Lee, Young Joo Park
  Endocrine Journal.2019; 66(7): 597.     CrossRef
• Total thyroidectomy's association with survival in papillary thyroid cancers and the high proportion of total thyroidectomy in low-risk patients: Analysis of Korean nationwide data
  Hyun-Soo Zhang, Eun-Kyung Lee, Yuh-Seog Jung, Byung-Ho Nam, Kyu-Won Jung, Hyun-Joo Kong, Young-Joo Won, Boyoung Park
  Surgery.2019; 165(3): 629.     CrossRef
• Individualized Follow-Up Strategy for Patients with an Indeterminate Response to Initial Therapy for Papillary Thyroid Carcinoma
  Hye-Seon Oh, Jong Hwa Ahn, Eyun Song, Ji Min Han, Won Gu Kim, Tae Yong Kim, Won Bae Kim, Young Kee Shong, Min Ji Jeon
  Thyroid.2019; 29(2): 209.     CrossRef
• Differentiated Thyroid Cancer and Radioactive Iodine: Past, Present and Future
  Jaetae Lee, Il Jo
  International Journal of Thyroidology.2019; 12(2): 71.     CrossRef
• Diagnostic performance of HMGA2 gene expression for differentiation of malignant thyroid nodules: A systematic review and meta‐analysis
  Bo Hyun Kim, Seong Jang Kim, Mijin Kim, Sang‐Woo Lee, Shin Young Jeong, Kyoungjune Pak, Keunyoung Kim, In Joo Kim
  Clinical Endocrinology.2018; 89(6): 856.     CrossRef
• Ultrasound risk evaluation of thyroid nodules that are “unspecified” in the 2015 American Thyroid Association management guidelines
  Luying Gao, Xuehua Xi, Juanjuan Wang, Xiao Yang, Ying Wang, Shenling Zhu, Xingjian Lai, Xiaoyan Zhang, Ruina Zhao, Bo Zhang
  Medicine.2018; 97(52): e13914.     CrossRef
• Refining the eighth edition AJCC TNM classification and prognostic groups for papillary thyroid cancer with lateral nodal metastasis
  Hye In Kim, Kyunga Kim, So Young Park, Jun-Ho Choe, Jung-Han Kim, Jee Soo Kim, Young Lyun Oh, Soo Yeon Hahn, Jung Hee Shin, Hyeon Seon Ahn, Sun Wook Kim, Tae Hyuk Kim, Jae Hoon Chung
  Oral Oncology.2018; 78: 80.     CrossRef
• Thyroid cancer surgery guidelines in an era of de-escalation
  K.J. Kovatch, C.W. Hoban, A.G. Shuman
  European Journal of Surgical Oncology.2018; 44(3): 297.     CrossRef
• Changes in Serum Thyroglobulin Levels After Lobectomy in Patients with Low-Risk Papillary Thyroid Cancer
  Suyeon Park, Min Ji Jeon, Hye-Seon Oh, Yu-Mi Lee, Tae-Yon Sung, Minkyu Han, Ji Min Han, Tae Yong Kim, Ki-Wook Chung, Won Bae Kim, Young Kee Shong, Won Gu Kim
  Thyroid.2018; 28(8): 997.     CrossRef
• Study Protocol of Multicenter Prospective Cohort Study of Active Surveillance on Papillary Thyroid Microcarcinoma (MAeSTro)
  Jae Hoon Moon, Ji-hoon Kim, Eun Kyung Lee, Kyu Eun Lee, Sung Hye Kong, Yeo Koon Kim, Woo-jin Jung, Chang Yoon Lee, Roh-Eul Yoo, Yul Hwangbo, Young Shin Song, Min Joo Kim, Sun Wook Cho, Su-jin Kim, Eun Jae Jung, June Young Choi, Chang Hwan Ryu, You Jin Lee
  Endocrinology and Metabolism.2018; 33(2): 278.     CrossRef
• Low-Dose Radioactive Iodine Ablation Is Sufficient in Patients With Small Papillary Thyroid Cancer Having Minor Extrathyroidal Extension and Central Lymph Node Metastasis (T3 N1a): Reply
  Minjung Seo, Yon Seon Kim, Jong Cheol Lee, Myung Woul Han, Eun Sook Kim, Kyung Bin Kim, Seol Hoon Park
  Clinical Nuclear Medicine.2018; 43(8): 635.     CrossRef
• Diagnosis and treatment of low-risk papillary thyroid microcarcinoma
  Jae Hoon Moon, Young Joo Park
  Journal of the Korean Medical Association.2018; 61(4): 232.     CrossRef
• Efficacy of a Home-Based Exercise Program After Thyroidectomy for Thyroid Cancer Patients
  Kyunghee Kim, Mee Ock Gu, Jung Hwa Jung, Jong Ryeal Hahm, Soo Kyoung Kim, Jin Hyun Kim, Seung Hoon Woo
  Thyroid.2018; 28(2): 236.     CrossRef
• Genome-Wide Association Study Reveals Distinct Genetic Susceptibility of Thyroid Nodules From Thyroid Cancer
  Yul Hwangbo, Eun Kyung Lee, Ho-Young Son, Sun-Wha Im, Soo-Jung Kwak, Ji Won Yoon, Min Joo Kim, Jeongseon Kim, Hoon Sung Choi, Chang Hwan Ryu, You Jin Lee, Jong-Il Kim, Nam H Cho, Young Joo Park
  The Journal of Clinical Endocrinology & Metabolism.2018; 103(12): 4384.     CrossRef
• Active Surveillance of Low-Risk Papillary Thyroid Microcarcinoma: A Multi-Center Cohort Study in Korea
  Hye-Seon Oh, Jeonghoon Ha, Hye In Kim, Tae Hyuk Kim, Won Gu Kim, Dong-Jun Lim, Tae Yong Kim, Sun Wook Kim, Won Bae Kim, Young Kee Shong, Jae Hoon Chung, Jung Hwan Baek
  Thyroid.2018; 28(12): 1587.     CrossRef
• Ultrasound criteria for risk stratification of thyroid nodules in the previously iodine deficient area of Austria - a single centre, retrospective analysis
  Christina Tugendsam, Veronika Petz, Wolfgang Buchinger, Brigitta Schmoll-Hauer, Iris Pia Schenk, Karin Rudolph, Michael Krebs, Georg Zettinig
  Thyroid Research.2018;[Epub]     CrossRef
• Practical Initial Risk Stratification Based on Lymph Node Metastases in Pediatric and Adolescent Differentiated Thyroid Cancer
  Min Ji Jeon, Young Nam Kim, Tae-Yong Sung, Suck Joon Hong, Yoon Young Cho, Tae Yong Kim, Young Kee Shong, Won Bae Kim, Sun Wook Kim, Jae Hoon Chung, Tae Hyuk Kim, Won Gu Kim
  Thyroid.2018; 28(2): 193.     CrossRef
• Current Radiological Approach in Thyroid Nodules
  Duzgun Yildirim, Deniz Alis, Sabri Sirolu, Cesur Samanci, Fethi Emre Ustabasioglu, Bulent Colakoglu
  Journal of Cancer Therapy.2017; 08(05): 423.     CrossRef
• A new paradigm in low-risk papillary microcarcinoma: active surveillance
  Alex González Bóssolo, Michelle Mangual Garcia, Paula Jeffs González, Miosotis Garcia, Guillermo Villarmarzo, Jose Hernán Martinez
  Endocrinology, Diabetes & Metabolism Case Reports.2017;[Epub]     CrossRef
• Serial Neck Ultrasonographic Evaluation of Changes in Papillary Thyroid Carcinoma During Pregnancy
  Hye-Seon Oh, Won Gu Kim, Suyeon Park, Mijin Kim, Hyemi Kwon, Min Ji Jeon, Jeong Hyun Lee, Jung Hwan Baek, Dong Eun Song, Tae Yong Kim, Young Kee Shong, Won Bae Kim
  Thyroid.2017; 27(6): 773.     CrossRef
• Restratification of survival prognosis of N1b papillary thyroid cancer by lateral lymph node ratio and largest lymph node size
  Hye In Kim, Tae Hyuk Kim, Jun‐Ho Choe, Jung‐Han Kim, Jee Soo Kim, Young Lyun Oh, Soo Yeon Hahn, Jung Hee Shin, Hye Won Jang, Young Nam Kim, Hosu Kim, Hyeon Seon Ahn, Kyunga Kim, Sun Wook Kim, Jae Hoon Chung
  Cancer Medicine.2017; 6(10): 2244.     CrossRef
• Comparison on Fine Needle Aspiration Cytology (FNAC) and Thyroid Ultrasonography in Management of Thyroid Nodules
  Sandini A Gunaratne
  International Clinical Pathology Journal.2017;[Epub]     CrossRef
• Current Practices of Thyroid Fine-Needle Aspiration in Asia: A Missing Voice
  Andrey Bychkov, Kennichi Kakudo, SoonWon Hong
  Journal of Pathology and Translational Medicine.2017; 51(6): 517.     CrossRef
• Clinical outcomes after delayed thyroid surgery in patients with papillary thyroid microcarcinoma
  Min Ji Jeon, Won Gu Kim, Hyemi Kwon, Mijin Kim, Suyeon Park, Hye-Seon Oh, Minkyu Han, Tae-Yon Sung, Ki-Wook Chung, Suck Joon Hong, Tae Yong Kim, Young Kee Shong, Won Bae Kim
  European Journal of Endocrinology.2017; 177(1): 25.     CrossRef
• Articles inEndocrinology and Metabolismin 2016
  Won-Young Lee
  Endocrinology and Metabolism.2017; 32(1): 62.     CrossRef
• The Impact of Thyroid Nodule Size and Fine-Needle Aspiration Biopsy Result on the Risk of Malignancy in the Patients Who Underwent Thyroidectomy
  Hwibin Im, Yu-Young Park, Jae-Gu Cho, Seung-Kuk Baek, Soon-Young Kwon, Kwang-Yoon Jung, Jeong-Soo Woo
  Korean Journal of Otorhinolaryngology-Head and Neck Surgery.2017; 60(6): 308.     CrossRef
• Active Surveillance of Papillary Thyroid Microcarcinoma: A Mini-Review from Korea
  Tae Yong Kim, Young Kee Shong
  Endocrinology and Metabolism.2017; 32(4): 399.     CrossRef

Autoimmune thyroid disease (AITD) includes hyperthyroid Graves disease, hypothyroid autoimmune thyroiditis, and subtle subclinical thyroid dysfunctions. AITD is caused by interactions between genetic and environmental predisposing factors and results in autoimmune deterioration. Data on polymorphisms in the AITD susceptibility genes, related environmental factors, and dysregulation of autoimmune processes have accumulated over time. Over the last decade, there has been progress in the clinical field of AITD with respect to the available diagnostic and therapeutic methods as well as clinical consensus. The updated clinical guidelines allow practitioners to identify the most reasonable and current approaches for proper management. In this review, we focus on recent advances in understanding the genetic and environmental pathogenic mechanisms underlying AITD and introduce the updated set of clinical guidelines for AITD management. We also discuss other aspects of the disease such as management of subclinical thyroid dysfunction, use of levothyroxine plus levotriiodothyronine in the treatment of autoimmune hypothyroidism, risk assessment of long-standing antithyroid drug therapy in recurrent Graves' hyperthyroidism, and future research needs.

Citations

Citations to this article as recorded by  

• A Mendelian randomization study of the effect of serum 25-hydroxyvitamin D levels on autoimmune thyroid disease
  Yunfeng Yu, Xinyu Yang, Jingyi Wu, Xueli Shangguan, Siyang Bai, Rong Yu
  Frontiers in Immunology.2024;[Epub]     CrossRef
• Therapeutic Potential of CRISPR/Cas in Hashimoto's Thyroiditis: A Comprehensive Review
  Apoorva Upreti, Sayali Mukherjee
  Current Gene Therapy.2024; 24(3): 179.     CrossRef
• Salenio: clinical study design
  Domenico Parmeggiani, Paola Bassi, Maddalena Claudia Donnarumma, Chiara Colonnese, Vincenzo Ieluzzi, Laura Pacca, Chiara Agresti, Massimo Agresti
  Endocrinology&Metabolism International Journal.2023; 11(1): 1.     CrossRef
• Medical Applications of Molecular Biotechnologies in the Context of Hashimoto’s Thyroiditis
  Maria Trovato, Andrea Valenti
  Diagnostics.2023; 13(12): 2114.     CrossRef
• IMMUNOHISTOCHEMICAL CHARACTERISTICS OF THYROID GLAND CHANGES IN PATIENTS WITH AUTOIMMUNE THYROIDITIS
  F. G. Sadikhov
  World of Medicine and Biology.2023; 19(84): 139.     CrossRef
• The C55A Single Nucleotide Polymorphism in CTLA-4 Gene, a New Possible Biomarker in Thyroid Autoimmune Pathology Such as Hashimoto’s Thyroiditis
  Alin-Dan Chiorean, Mihaela Laura Vica, Ștefana Bâlici, Gheorghe Zsolt Nicula, Nicoleta Răcătăianu, Mădălina Adriana Bordea, Laura-Mihaela Simon, Horea Vladi Matei
  Diagnostics.2023; 13(15): 2517.     CrossRef
• USING LASER PHOTODYNAMIC THERAPY IN THE TREATMENT OF AUTOIMMUNE THYROIDITIS
  F. G. Sadikhov
  World of Medicine and Biology.2023; 19(85): 166.     CrossRef
• Autoimmune thyroiditis in different age groups and subjects of reproductive age in Adzhariya population
  N. G. Tchelidze, S. Z. Glonti, D. Sh. Baratashvili, N. O. Kedelidze, J. Yu. Ungiadze, I. I. Nakashidze
  Obstetrics, Gynecology and Reproduction.2022; 16(1): 8.     CrossRef
• Alterations and Mechanism of Gut Microbiota in Graves’ Disease and Hashimoto’s Thyroiditis
  Hong Zhao, Lijie Yuan, Dongli Zhu, Banghao Sun, Juan Du, Jingyuan Wang
  Polish Journal of Microbiology.2022; 71(2): 173.     CrossRef
• The association of six autoimmune bullous diseases with thyroid disorders: a population‐based study
  K. Kridin, F. Hübner, R. Linder, E. Schmidt
  Journal of the European Academy of Dermatology and Venereology.2022; 36(10): 1826.     CrossRef
• Investigation of comorbid autoimmune diseases in women with autoimmune bullous diseases: An interplay of autoimmunity and practical implications
  Meropi Karakioulaki, Dedee F. Murrell, Aikaterini Kyriakou, Aikaterini Patsatsi
  International Journal of Women’s Dermatology.2022; 8(3): e053.     CrossRef
• Best Achievements in Translational and Basic Thyroidology in 2020
  Sun Wook Cho, Young Joo Park
  Endocrinology and Metabolism.2021; 36(1): 36.     CrossRef
• Incidence and Clinical Implications of Autoimmune Thyroiditis in the Development of Acne in Young Patients
  Laura Endres, Delia Mirela Tit, Simona Bungau, Nicoleta Anamaria Pascalau, Laura Maghiar Țodan, Erika Bimbo-Szuhai, Gabriela Mariana Iancu, Nicoleta Negrut
  Diagnostics.2021; 11(5): 794.     CrossRef
• Attaining Euthyroidism - Seal the Loopholes
  Payel Biswas, Subhankar Chatterjee
  International Journal of Thyroidology.2021; 14(1): 69.     CrossRef
• Cardiac Autonomic Modulation and Anti-Thyroid Peroxidase (TPO) Antibodies in Subclinical Hypothyroidism – Does Any Correlation Exist?
  Manisha Mavai, Dr Bharti Bhandari , Anish Singhal, Sandeep K Mathur
  Cureus.2021;[Epub]     CrossRef
• Sensibilidade ao glúten e tireoidite de Hashimoto: uma interação viável
  Larissa Barros Pinto Franco, Fernanda Neves Pinto, Claudia Teresa Bento, Carla Viana Dendasck
  Revista Científica Multidisciplinar Núcleo do Conhecimento.2021; : 110.     CrossRef
• Chronic urticaria and thyroid pathology
  Sandra Nora Gonzalez-Diaz, Mario Sanchez-Borges, Diana Maria Rangel-Gonzalez, Rosa Ivett Guzman-Avilan, Jose Ignacio Canseco-Villarreal, Alfredo Arias-Cruz
  World Allergy Organization Journal.2020; 13(3): 100101.     CrossRef
• Genome-Wide Analysis Identifies Two Susceptibility Loci for Positive Thyroid Peroxidase and Thyroglobulin Antibodies
  Antonela Matana, Thibaud Boutin, Vesela Torlak, Dubravka Brdar, Ivana Gunjača, Ivana Kolčić, Vesna Boraska Perica, Ante Punda, Ozren Polašek, Maja Barbalić, Caroline Hayward, Tatijana Zemunik
  The Journal of Clinical Endocrinology & Metabolism.2020; 105(3): 944.     CrossRef
• Iodine and bromine in fish consumed by indigenous peoples of the Russian Arctic
  Nikita Sobolev, Andrey Aksenov, Tatiana Sorokina, Valery Chashchin, Dag G. Ellingsen, Evert Nieboer, Yulia Varakina, Elena Plakhina, Alexandra Onuchina, Magny Skinlo Thomassen, Yngvar Thomassen
  Scientific Reports.2020;[Epub]     CrossRef
• Significance of arsenic and lead in Hashimoto's thyroiditis demonstrated on thyroid tissue, blood, and urine samples
  Aleksandar Stojsavljević, Branislav Rovčanin, Jovana Jagodić, Danijela Drašković Radojković, Ivan Paunović, Marija Gavrović-Jankulović, Dragan Manojlović
  Environmental Research.2020; 186: 109538.     CrossRef
• Prognostic Value of Caspase-1, Interleukin-1β, Tumor Necrosis Factor-α and Interleukin-18 Activity in Patients with Gastroesophageal Reflux Disease and Autoimmune Thyroiditis
  T. M. Pasiieshvili, O. M. Kovaloyva, L. M. Pasiieshvili , N. M. Zhelezniakova
  Ukraïnsʹkij žurnal medicini, bìologìï ta sportu.2020; 5(4): 202.     CrossRef
• A historical excursus of diagnostic methods for Hashimoto thyroiditis and Graves' disease
  Maria Trovato
  Gazzetta Medica Italiana Archivio per le Scienze Mediche.2020;[Epub]     CrossRef
• The value of preoperative antithyroidperoxidase antibody as a novel predictor of recurrence in papillary thyroid carcinoma
  Eyun Song, Hye‐Seon Oh, Min Ji Jeon, Ki Wook Chung, Suck Joon Hong, Jin Sook Ryu, Jung Hwan Baek, Jeong Hyun Lee, Won Gu Kim, Won Bae Kim, Young Kee Shong, Tae Yong Kim
  International Journal of Cancer.2019; 144(6): 1414.     CrossRef
• Hydatid cyst of the thyroid gland with tracheal fistula: A case report and review of the literature
  Tiemin Jiang, Qiang Guo, Bo Ran, Ruiqing Zhang, Tuerganaili Aji, Yingmei Shao
  Experimental and Therapeutic Medicine.2019;[Epub]     CrossRef
• Thyroid diseases and skin autoimmunity
  Enke Baldini, Teresa Odorisio, Chiara Tuccilli, Severino Persechino, Salvatore Sorrenti, Antonio Catania, Daniele Pironi, Giovanni Carbotta, Laura Giacomelli, Stefano Arcieri, Massimo Vergine, Massimo Monti, Salvatore Ulisse
  Reviews in Endocrine and Metabolic Disorders.2018; 19(4): 311.     CrossRef
• Does severe vitamin D deficiency impact obstetric outcomes in pregnant women with thyroid autoimmunity?
  Halenur Bozdag, Esra Akdeniz
  The Journal of Maternal-Fetal & Neonatal Medicine.2018; : 1.     CrossRef
• Constitutive Changes in Circulating Follicular Helper T Cells and Their Subsets in Patients with Graves’ Disease
  Yan Liu, Xinwang Yuan, Xiaofang Li, Dawei Cui, Jue Xie
  Journal of Immunology Research.2018; 2018: 1.     CrossRef
• Comorbidity of autoimmune thyroid disorders and psychiatric disorders during the postpartum period: a Danish nationwide register-based cohort study
  V. Bergink, V. J. M. Pop, P. R. Nielsen, E. Agerbo, T. Munk-Olsen, X. Liu
  Psychological Medicine.2018; 48(8): 1291.     CrossRef
• Spontaneous conversion from Graves’ disease to Hashimoto’s thyroiditis: a case report
  Muharrem Bayrak, Kenan Çadırcı, Emine Kartal Baykan, Ünsal Aydın, Ayşe Çarlıoğlu
  Ortadoğu Tıp Dergisi.2018; 10(1): 81.     CrossRef
• Role of T Follicular Helper (Tfh) Cells Plasticity in Autoimmune Thyroiditis among Hepatitis C Virus Infection
  Helal F Hetta
  Gastroenterology & Hepatology: Open Access.2017;[Epub]     CrossRef
• Variants of Interleukin-22 Gene Confer Predisposition to Autoimmune Thyroid Disease
  Rong-hua Song, Qian Li, Wen Wang, Qiu-ming Yao, Xiao-qing Shao, Jin-an Zhang
  International Journal of Endocrinology.2017; 2017: 1.     CrossRef
• Thyroid Involvement in Hepatitis C Virus-Infected Patients with/without Mixed Cryoglobulinemia
  Clodoveo Ferri, Michele Colaci, Poupak Fallahi, Silvia Martina Ferrari, Alessandro Antonelli, Dilia Giuggioli
  Frontiers in Endocrinology.2017;[Epub]     CrossRef
• Articles inEndocrinology and Metabolismin 2016
  Won-Young Lee
  Endocrinology and Metabolism.2017; 32(1): 62.     CrossRef

Thyroid dysfunction during pregnancy can result in serious complications for both the mother and infant; however, these complications can be prevented by optimal treatment of maternal overt thyroid dysfunction. Although several studies have demonstrated that maternal subclinical hypothyroidism is associated with obstetric complications and neurocognitive impairments in offspring, there is limited evidence that levothyroxine treatment can improve these complications. Therefore, most professional societies do not recommend universal screening for thyroid dysfunction during pregnancy, and instead recommend a case-finding approach in which only high-risk women are tested. However, recent studies have estimated that targeted thyroid function testing misses approximately 30% to 55% of hypothyroidism cases in pregnant women, and some associations and researchers have recommended universal screening of pregnant women to facilitate the early detection and treatment of overt hypothyroidism. This review summarizes recent data on thyroid function test changes, thyroid functional disorder management, and thyroid screening during pregnancy.

Citations

Citations to this article as recorded by  

• The Effect of Inflammatory Markers in the Hemogram Parameters of Pregnant Women with Thyroid Disease on Obstetric and Neonatal Outcomes
  Funda DEMİREL, Ünal TURKAY
  Düzce Tıp Fakültesi Dergisi.2023; 25(3): 231.     CrossRef
• Enfermedades tiroideas y embarazo en una unidad de cuidados intensivos. Experiencia 2014-2019
  J.G. Vázquez-Rodríguez, A.C. Andrade-Rodríguez
  Clínica e Investigación en Ginecología y Obstetricia.2021; 48(3): 100662.     CrossRef
• Decreased Expression of Ileal Thyroid Hormone Transporters in a Hypothyroid Patient: A Case Report
  Chae Won Chung, Eun Young Mo, Gyung Seo Jung, Yoo Hyung Kim, Sun Wook Cho, Do Joon Park, Jeong Mo Bae, Young Joo Park
  Frontiers in Endocrinology.2021;[Epub]     CrossRef
• Tiroidectomía en paciente embarazada con enfermedad de Graves sin respuesta a tratamiento médico: reporte de caso
  Elly Morros González, Leonardo Javier Rojas Melo, Viviana Cruz Ramírez, Angélica Imitola
  Universitas Médica.2020;[Epub]     CrossRef
• Thyroid disorders in subfertility and early pregnancy
  Samantha Anandappa, Mamta Joshi, Lukasz Polanski, Paul V. Carroll
  Therapeutic Advances in Endocrinology and Metabolism.2020; 11: 204201882094585.     CrossRef
• Addressing thyroid dysfunction in pregnancy
  Teodora Onciu, Remus Şipoş
  Medic.ro.2020; 3(135): 48.     CrossRef
• Antenatal/early postnatal hypothyroidism increases the contribution of Rho-kinase to contractile responses of mesenteric and skeletal muscle arteries in adult rats
  Dina K. Gaynullina, Svetlana I. Sofronova, Anastasia A. Shvetsova, Ekaterina K. Selivanova, Anna P. Sharova, Andrey A. Martyanov, Olga S. Tarasova
  Pediatric Research.2018; 84(1): 112.     CrossRef
• Voluntary exercise training restores anticontractile effect of NO in coronary arteries of adult rats with antenatal/early postnatal hypothyroidism
  D.K. Gaynullina, A.A. Borzykh, S.I. Sofronova, E.K. Selivanova, A.A. Shvetsova, A.A. Martyanov, I.V. Kuzmin, O.S. Tarasova
  Nitric Oxide.2018; 74: 10.     CrossRef
• Impact of positive thyroid autoimmunity on pregnant women with subclinical hypothyroidism
  Cristina López-Tinoco, Amparo Rodríguez-Mengual, Almudena Lara-Barea, Julia Barcala, Laura Larrán, Ana Saez-Benito, Manuel Aguilar-Diosdado
  Endocrinología, Diabetes y Nutrición (English ed.).2018; 65(3): 150.     CrossRef
• Impacto de la autoinmunidad antitiroidea positiva en gestantes con hipotiroidismo subclínico
  Cristina López-Tinoco, Amparo Rodríguez-Mengual, Almudena Lara-Barea, Julia Barcala, Laura Larrán, Ana Saez-Benito, Manuel Aguilar-Diosdado
  Endocrinología, Diabetes y Nutrición.2018; 65(3): 150.     CrossRef
• Articles inEndocrinology and Metabolismin 2016
  Won-Young Lee
  Endocrinology and Metabolism.2017; 32(1): 62.     CrossRef
• Maternal hypothyroidism: An overview of current experimental models
  Mahboubeh Ghanbari, Asghar Ghasemi
  Life Sciences.2017; 187: 1.     CrossRef

Medullary thyroid carcinoma (MTC) is a rare neuroendocrine tumor derived from the thyroid C cells producing calcitonin. MTC accounts for 0.6% of all thyroid cancers and incidence of MTC increased steadily between 1997 and 2011 in Korea. It occurs either sporadically or in a hereditary form based on germline rearranged during transfection (RET) mutations. MTC can be cured only by complete resection of the thyroid tumor and any loco-regional metastases. The most appropriate treatment is still less clear in patients with residual or recurrent disease after initial surgery or those with distant metastases because most patients even with metastatic disease have indolent courses with slow progression for several years and MTC is not responsive to either radioactive iodine therapy or thyroid-stimulating hormone suppression. Recently, two tyrosine kinase inhibitors (TKIs), vandetanib and cabozantinib, are approved for use in patients with advanced, metastatic or progressive MTC. In this review, we summarize the current approach according to revised American Thyroid Association guidelines and recent advances in systemic treatment such as TKIs for patients with persistent or recurrent MTC after surgery.

Citations

Citations to this article as recorded by  

• [68Ga]Ga-DOTA-FAPI-04 PET/CT depicts metastases from medullary thyroid cancer that [68Ga]Ga-DOTATOC PET/CT missed
  Akram Al-Ibraheem, Salem Fandi Alyasjeen, Ahmed Saad Abdlkadir, Areej Abu Sheikha
  European Journal of Nuclear Medicine and Molecular Imaging.2023; 50(13): 4112.     CrossRef
• Molecular Mechanism and Clinical Application of Thyroid Cancer
  ·如孜 卡地力艳
  Advances in Clinical Medicine.2023; 13(12): 20543.     CrossRef
• Research Progress of the Molecular Mechanism of Antithyroid Cancer Activity of Shikonin
  Chunguang Sun, Lin Liao
  Current Molecular Pharmacology.2023;[Epub]     CrossRef
• Multiple endocrine neoplasia 2: an overview
  B Saravana-Bawan, JD Pasternak
  Therapeutic Advances in Chronic Disease.2022; 13: 204062232210792.     CrossRef
• Total thyroidectomy vs thyroid lobectomy for localized medullary thyroid cancer in adults: A propensity-matched survival analysis
  Weili Liang, Jinyuan Shi, Hui Zhang, Guixu Lv, Tiantian Wang, Yong Wang, Bin Lv, Luchuan Li, Qingdong Zeng, Lei Sheng
  Surgery.2022; 172(5): 1385.     CrossRef
• Naphthoquinones and derivatives as potential anticancer agents: An updated review
  Md Mominur Rahman, Md Rezaul Islam, Shopnil Akash, Sheikh Shohag, Limon Ahmed, Fatema Akter Supti, Abdur Rauf, Abdullah S.M. Aljohani, Waleed Al Abdulmonem, Anees Ahmed Khalil, Rohit Sharma, Muthu Thiruvengadam
  Chemico-Biological Interactions.2022; 368: 110198.     CrossRef
• Metformin Decreases Serum Thyroglobulin Concentration in Nonmedullary Thyroid Carcinoma
  Celina Caetano, Paola Tabaro Pico, Charan Singh, Beatriz Tendler, Diana M Malchoff, Carl D Malchoff
  Journal of the Endocrine Society.2022;[Epub]     CrossRef
• Long non-coding RNA LINC00488 facilitates thyroid cancer cell progression through miR-376a-3p/PON2
  Fuyuan Xie, Longgen Li, Yuting Luo, Rensheng Chen, Jinhong Mei
  Bioscience Reports.2021;[Epub]     CrossRef
• Decision Making When Cancer Becomes Chronic: Needs Assessment for a Web-Based Medullary Thyroid Carcinoma Patient Decision Aid
  Danielle Shojaie, Aubri S Hoffman, Ruth Amaku, Maria E Cabanillas, Julie Ann Sosa, Steven G Waguespack, Mark E Zafereo, Mimi I Hu, Elizabeth E Grubbs
  JMIR Formative Research.2021; 5(7): e27484.     CrossRef
• Long Non-coding RNA RUNDC3A-AS1 Promotes Lung Metastasis of Thyroid Cancer via Targeting the miR-182-5p/ADAM9
  Dawei Ma, Yan Zhu, Xiao Zhang, Jia Zhang, Wei Chen, Xinyuan Chen, Yichun Qian, Yanbin Zhao, Tingting Hu, Zhangyu Yao, Wei Zhao, Yuan Zhang, Fangzhou Liu
  Frontiers in Cell and Developmental Biology.2021;[Epub]     CrossRef
• Effects of marital status on survival of medullary thyroid cancer stratified by age
  Lei Ai, Ning Li, Hai‐Long Tan, Bo Wei, Ya‐Xin Zhao, Pei Chen, Hui‐Yu Hu, Mian Liu, Deng‐Jie Ou‐Yang, Zi‐en Qin, Peng Huang, Shi Chang
  Cancer Medicine.2021; 10(24): 8829.     CrossRef
• The prognostic value of lymph node ratio in Medullary thyroid carcinoma: A multi-center study
  Tal Rozenblat, Dania Hirsch, Eyal Robenshtok, Simona Grozinsky-Glasberg, David J. Gross, Haggi Mazeh, Carlos Benbassat, Orit Twito, Sigal Levy, Aviram Mizrachi, Thomas Shpitzer, Gideon Bachar
  European Journal of Surgical Oncology.2020; 46(11): 2023.     CrossRef

• Multiple Auer Rods in Fine-Needle Aspiration Smears of Medullary Thyroid Carcinoma: An Unusual Finding

  
  Maryam Mohammadnia Avval, Perikala Vijayananda Kumar, Fereydoon Dehghani
  International Medical Case Reports Journal.2020; Volume 13: 85.     CrossRef
• Lymph Node Metastases of Medullary Thyroid Cancer: Role of Calcitonin in the Washout Fluid of Fine-Needle Aspiration
  Bernardo Marques, Nuno Cunha, Raquel G. Martins, Ana Rita Elvas, Joana Couto, Jacinta Santos, Teresa Martins, Ana Paula Moniz, Olga Ilhéu, Frederico Valido, Fernando Rodrigues
  International Journal of Endocrinology.2020; 2020: 1.     CrossRef
• Efficacy and Safety of Vandetanib in Progressive and Symptomatic Medullary Thyroid Cancer: Post Hoc Analysis From the ZETA Trial
  Michael C. Kreissl, Lars Bastholt, Rossella Elisei, Robert Haddad, Ole Hauch, Barbara Jarząb, Bruce Robinson, Raffaella Colzani, Meredith Foster, Richard Weiss, Martin Schlumberger
  Journal of Clinical Oncology.2020; 38(24): 2773.     CrossRef
• Medullary thyroid cancer: epidemiological pattern and factors contributing to recurrence and metastasis
  O Hamdy, S Awny, IH Metwally
  The Annals of The Royal College of Surgeons of England.2020; 102(7): 499.     CrossRef
• Carcinoma medular de tiroides estadio iv y gestación
  B. Sánchez Lechuga, C. López Tinoco, I. Gavilán Villarejo, F.J. Vílchez López, M. Aguilar Diosdado
  Clínica e Investigación en Ginecología y Obstetricia.2019; 46(1): 35.     CrossRef
• Bildgebung beim medullären Schilddrüsenkarzinom
  M. Uhrig, S. Delorme
  Der Radiologe.2019; 59(11): 992.     CrossRef
• Recent Development of Nuclear Molecular Imaging in Thyroid Cancer
  Huiting Liu, Xiaoqin Wang, Ran Yang, Wenbing Zeng, Dong Peng, Jason Li, Hu Wang
  BioMed Research International.2018; 2018: 1.     CrossRef
• Radioguided hepatic resection with l -DOPA in metastatic medullary thyroid carcinoma
  Javier López-Gómez, Sevastian Medina-Ornelas, Ma. Alejandra Salazar-Álvarez, Mario Álvarez-Bojórquez, Noel Zaragoza-Cruz, Javier Melchor-Ruan, Alethia Álvarez-Cano
  Revista Española de Medicina Nuclear e Imagen Molecular (English Edition).2018; 37(4): 244.     CrossRef
• EF24 (a Curcumin Analog) and ZSTK474 Emphasize the Effect of Cabozantinib in Medullary Thyroid Cancer
  Loris Bertazza, Francesca Sensi, Elisabetta Cavedon, Sara Watutantrige-Fernando, Simona Censi, Jacopo Manso, Federica Vianello, Eric Casal Ide, Maurizio Iacobone, Raffaele Pezzani, Caterina Mian, Susi Barollo
  Endocrinology.2018; 159(6): 2348.     CrossRef
• Resección hepática radioguiada con 18 F-DOPA en un paciente con carcinoma medular de tiroides metastásico
  J. López-Gómez, S. Medina-Ornelas, M.A. Salazar-Álvarez, M. Álvarez-Bojórquez, N. Zaragoza-Cruz, J. Melchor-Ruan, A. Álvarez-Cano
  Revista Española de Medicina Nuclear e Imagen Molecular.2018; 37(4): 244.     CrossRef
• Genotypic characteristics and their association with phenotypic characteristics of hereditary medullary thyroid carcinoma in Korea
  Kyong Yeun Jung, Seok-Mo Kim, Min Joo Kim, Sun Wook Cho, Bup-Woo Kim, Yong Sang Lee, Jong Ju Jeong, Kee-Hyun Nam, Woong Youn Chung, Kyu Eun Lee, Eun-Jae Chung, Hyo Jeong Kim, Do Joon Park, Myung-Whun Sung, Cheong Soo Park, Bo Youn Cho, Young Joo Park, Han
  Surgery.2018; 164(2): 312.     CrossRef
• Thyroid cancer management
  Francesco Perri, Antonio Giordano, Salvatore Pisconti, Franco Ionna, Maria G. Chiofalo, Francesco Longo, Davide Leopardo, Giuseppina Della Vittoria Scarpati, Luciano Pezzullo
  Anti-Cancer Drugs.2018; 29(6): 483.     CrossRef
• Clinicopathological Significance and Prognosis of Medullary Thyroid Microcarcinoma: A Meta‐analysis
  Jin Hwa Kim, Jung‐Soo Pyo, Won Jin Cho
  World Journal of Surgery.2017; 41(10): 2551.     CrossRef
• A label-free electrochemical immunosensor based on gold nanoparticles and graphene oxide for the detection of tumor marker calcitonin
  Nawal A. Alarfaj, Maha F. El-Tohamy
  New Journal of Chemistry.2017; 41(19): 11029.     CrossRef
• Evaluation of in vitro and in vivo activity of a multityrosine kinase inhibitor, AL3810, against human thyroid cancer
  Qin Xie, Hui Chen, Jing Ai, Ying-lei Gao, Mei-yu Geng, Jian Ding, Yi Chen
  Acta Pharmacologica Sinica.2017; 38(11): 1533.     CrossRef
• Articles inEndocrinology and Metabolismin 2016
  Won-Young Lee
  Endocrinology and Metabolism.2017; 32(1): 62.     CrossRef

Citations

Citations to this article as recorded by  

• Association between atherosclerotic cardiovascular diseases risk and renal outcome in patients with type 2 diabetes mellitus
  Honghong Ren, Lijun Zhao, Yutong Zou, Yiting Wang, Junlin Zhang, Yucheng Wu, Rui Zhang, Tingli Wang, Jiali Wang, Yitao Zhu, Ruikun Guo, Huan Xu, Lin Li, Mark E. Cooper, Fang Liu
  Renal Failure.2021; 43(1): 477.     CrossRef
• Long-term effects of various types of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on changes in glomerular filtration rate in Korea
  Seo Yeon Baik, Hyunah Kim, So Jung Yang, Tong Min Kim, Seung-Hwan Lee, Jae Hyoung Cho, Hyunyong Lee, Hyeon Woo Yim, Kun-Ho Yoon, Hun-Sung Kim
  Frontiers of Medicine.2019; 13(6): 713.     CrossRef
• Analysis and comparison of the cost-effectiveness of statins according to the baseline low-density lipoprotein cholesterol level in Korea
  Y. J. Jeong, H. Kim, S. J. Baik, T. M. Kim, S. J. Yang, S.-H. Lee, J.-H. Cho, H. Lee, H. W. Yim, I. Y. Choi, K.-H. Yoon, H.-S. Kim
  Journal of Clinical Pharmacy and Therapeutics.2017; 42(3): 292.     CrossRef
• Comparison between Atorvastatin and Rosuvastatin in Renal Function Decline among Patients with Diabetes
  Eugene Han, Gyuri Kim, Ji-Yeon Lee, Yong-ho Lee, Beom Seok Kim, Byung-Wan Lee, Bong-Soo Cha, Eun Seok Kang
  Endocrinology and Metabolism.2017; 32(2): 274.     CrossRef

Citations

Citations to this article as recorded by  

• Is there a causal relationship between hypothyroidism and hyponatremia?
  Julie Chen
  Therapeutic Advances in Endocrinology and Metabolism.2023;[Epub]     CrossRef
• Endocrinopathy-induced euvolemic hyponatremia
  Talia Diker-Cohen, Benaya Rozen-Zvi, Dana Yelin, Amit Akirov, Eyal Robenshtok, Anat Gafter-Gvili, Daniel Shepshelovich
  Internal and Emergency Medicine.2018; 13(5): 679.     CrossRef

Citations

Citations to this article as recorded by  

• Rescue of High Glucose Impairment of Cultured Human Osteoblasts Using Cinacalcet and Parathyroid Hormone
  V. A. Shahen, A. Schindeler, M. S. Rybchyn, C. M. Girgis, B. Mulholland, R. S. Mason, I. Levinger, T. C. Brennan-Speranza
  Calcified Tissue International.2023; 112(4): 452.     CrossRef
• Factors Related to the Occurrence and Number of Chronic Diabetic Complications in Patients with Type 2 Diabetes Mellitus: Utilizing The National Health Insurance Service-National Health Screening Cohort in Korea, 2002~2015
  Haejung Lee, Misoon Lee, Gaeun Park, Ah Reum Khang
  Journal of Korean Gerontological Nursing.2022; 24(1): 22.     CrossRef
• Prevalence of and Risk Factors for Diabetic Retinopathy and Diabetic Macular Edema in Patients with Early- and Late-Onset Diabetes Mellitus
  Yu Wang, Zhong Lin, Gang Zhai, Xiao Xia Ding, Liang Wen, Dong Li, Bo Zou, Ke Mi Feng, Yuan Bo Liang, Cong Xie
  Ophthalmic Research.2022; 65(3): 293.     CrossRef
• Associations of Age at Diagnosis and Duration of Diabetes With Morbidity and Mortality Among Older Adults
  Christine T. Cigolle, Caroline S. Blaum, Chen Lyu, Jinkyung Ha, Mohammed Kabeto, Judy Zhong
  JAMA Network Open.2022; 5(9): e2232766.     CrossRef
• Chart review of diagnostic methods, baseline characteristics and symptoms for European patients with pancreatic cancer
  Alfredo Carrato, Davide Melisi, Gerald Prager, Christoph B Westphalen, Anabel Ferreras, Nathalie D’Esquermes, Julien Taieb, Teresa M Mercadé
  Future Oncology.2021; 17(15): 1843.     CrossRef
• Distinction of cardiometabolic profiles among people ≥75 years with type 2 diabetes: a latent profile analysis
  Antoine CHRISTIAENS, Michel P. HERMANS, Benoit BOLAND, Séverine HENRARD
  BMC Endocrine Disorders.2019;[Epub]     CrossRef
• Validity of diagnostic codes and estimation of prevalence of diabetic foot ulcers using a large electronic medical record database
  Avivit Cahn, Talya Altaras, Tal Agami, Ori Liran, Colette E. Touaty, Michel Drahy, Rena Pollack, Itamar Raz, Gabriel Chodick, Inbar Zucker
  Diabetes/Metabolism Research and Reviews.2019;[Epub]     CrossRef
• Response: Comparison of Age of Onset and Frequency of Diabetic Complications in the Very Elderly Patients with Type 2 Diabetes (Endocrinol Metab2016;31:416-23, Bong-Ki Lee et al.)
  Eun-Hee Cho
  Endocrinology and Metabolism.2017; 32(1): 142.     CrossRef
• Letter: Comparison of Age of Onset and Frequency of Diabetic Complications in the Very Elderly Patients with Type 2 Diabetes (Endocrinol Metab2016;31:416-23, Bong-Ki Lee et al.)
  Mee Kyoung Kim
  Endocrinology and Metabolism.2017; 32(1): 140.     CrossRef

Citations

Citations to this article as recorded by  

• Prognosis of patients with extreme acidosis on admission to the emergency department: A retrospective cohort study
  Amichai Gutgold, Shaden Salameh, Jeries Nashashibi, Yonatan Gershinsky
  The American Journal of Emergency Medicine.2024; 76: 36.     CrossRef
• The critical role of pen needles and training in insulin delivery
  Tracey Sainsbury
  British Journal of Nursing.2024; 33(5): 242.     CrossRef
• Clinical characteristics of people with diabetic ketoacidosis at a clinic in The Gambia: a retrospective study
  Orighomisan F Agboghoroma, Modou Jobe, Karen Forrest
  Journal of Endocrinology, Metabolism and Diabetes of South Africa.2023; 28(1): 14.     CrossRef
• Elevated alanine transaminase is nonlinearly associated with in-hospital death in ICU-admitted diabetic ketoacidosis patients
  Qiaoling Liu, Chen Gong, Yunjie Geng, Jiuhong You
  Diabetes Research and Clinical Practice.2023; 197: 110555.     CrossRef
• Diabetic keto-acidosis in pancreatic diabetes – how is it different from DKA in type 1 or type 2 DM?
  Sunetra Mondal, Riddhi DasGupta, Moushumi Lodh, Ashok Parida, Mandira Haldar, Arunangshu Ganguly
  International Journal of Diabetes in Developing Countries.2023;[Epub]     CrossRef
• Comparative study of diabetic ketoacidosis in the elderly and non-elderly patients: A nine-year experience from an academic hospital in North India
  Ashok Kumar Pannu, Ravindran Kiran, Abhishek Kumar, Saurabh Chandrabhan Sharda, Mandip Bhatia, Atul Saroch, Pinaki Dutta, Navneet Sharma
  Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2023; 17(12): 102903.     CrossRef
• Clinical Profile and Outcome of Diabetic Ketoacidosis in Type 1 and Type 2 Diabetes: A Comparative Study
  Sachin Kamle, Madhuri Holay, Prashant Patil, Parimal Tayde
  Vidarbha Journal of Internal Medicine.2022; 32: 21.     CrossRef
• Effect of subjective tool based aerobic exercise on pulmonary functions in patients with type 2 diabetes mellitus – a feasibility RCT
  M. Saini, J. Kaur
  Comparative Exercise Physiology.2022; 18(3): 239.     CrossRef
• Clinical characteristics and outcomes of care in patients hospitalized with diabetic ketoacidosis
  Mohsen S. Eledrisi, Haifaa Alkabbani, Malk Aboawon, Aya Ali, Imad Alabdulrazzak, Maab Elhaj, Ashraf Ahmed, Hazim Alqahwachi, Joanne Daghfal, Salem A. Beshyah, Rayaz A. Malik
  Diabetes Research and Clinical Practice.2022; 192: 110041.     CrossRef
• An Audit of Factors Impacting the Time to Resolution of the Metabolic Parameters in Diabetic Ketoacidosis Patients
  Muath F AlWahbi , Sami H Alharbi, Saleh A Almesned, Faisal A Alfawzan, Rayan T Alsager, Abdullah A AlHojailan, Emad A Alfadhel, Fahad G Al-Harbi
  Cureus.2022;[Epub]     CrossRef
• Incidence of Diabetic Ketoacidosis among Adults with Type 1 Diabetes in Saudi Arabia: Systematic review
  Ayoub Ali Alshaikh, Rawan Zaifallh Alsalman, Nada Hamzah Albarqi, Razan Salem Alqahtani, Ali Ahmed Almontashri, Atheer Saud Alshahrani, Mohammed Abdullah Alshehri
  Pharmacophore.2022; 13(4): 105.     CrossRef
• Features and long‐term outcomes of patients hospitalized for diabetic ketoacidosis
  Michal Michaelis, Tzippy Shochat, Ilan Shimon, Amit Akirov
  Diabetes/Metabolism Research and Reviews.2021;[Epub]     CrossRef
• Incidence, characteristics and long-term outcomes of patients with diabetic ketoacidosis: a prospective prognosis cohort study in an emergency department
  Rachel Teixeira Leal Nunes, Carolina Frade Magalhães Girardin Pimentel Mota, Paulo Ricardo Gessolo Lins, Fernanda Salles Reis, Thais Castanheira de Freitas Resende, Ludmila de Andrade Barberino, Pedro Henrique Luiz da Silva, Aecio Flavio Teixeira de Gois
  Sao Paulo Medical Journal.2021; 139(1): 10.     CrossRef
• Management of diabetic ketoacidosis in special populations
  Mohsen S. Eledrisi, Salem A. Beshyah, Rayaz A. Malik
  Diabetes Research and Clinical Practice.2021; 174: 108744.     CrossRef
• Profile of diabetic ketoacidosis at the National Diabetes and Endocrine Center in Tripoli, Libya, 2015
  Aida Elkituni, Halla Elshwekh, Nesrein M. Bendala, Wafeya S. Atwear, Fawzia A. Aldaba, Abdulmunam M. Fellah
  Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2021; 15(3): 771.     CrossRef
• Frequency of Diabetic Ketoacidosis and Its Determinants Among Pediatric Diabetes Mellitus Patients in Northwest Ethiopia
  Atitegeb Abera Kidie, Ayenew Molla Lakew, Tiruneh Ayele
  Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.2021; Volume 14: 4819.     CrossRef
• Diabetic ketoacidosis
  Ketan K. Dhatariya, Nicole S. Glaser, Ethel Codner, Guillermo E. Umpierrez
  Nature Reviews Disease Primers.2020;[Epub]     CrossRef
• Risk and Relevance of Insulin Pump Therapy in the Aetiology of Ketoacidosis in People with Type 1 Diabetes
  Lena Christina Giessmann, Peter Herbert Kann
  Experimental and Clinical Endocrinology & Diabetes.2020; 128(11): 745.     CrossRef
• Clinical and biochemical profile, precipitants and prognostic factors of diabetic ketoacidosis: A retrospective study from a tertiary care center of north India
  Harpreet Singh, Atul Saroch, Ashok Kumar Pannu, H.J. Sachin, Navneet Sharma, Pinaki Dutta
  Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2019; 13(4): 2357.     CrossRef
• Sudden death due to diabetic ketoacidosis following power failure of an insulin pump: Autopsy and pump data
  Mette Louise Blouner Gram Kjærulff, Birgitte Schmidt Astrup
  Journal of Forensic and Legal Medicine.2019; 63: 34.     CrossRef
• Defining and characterising diabetic ketoacidosis in adults
  Ketan K. Dhatariya
  Diabetes Research and Clinical Practice.2019; 155: 107797.     CrossRef
• Effects of diabetic ketoacidosis in the respiratory system
  Alice Gallo de Moraes, Salim Surani
  World Journal of Diabetes.2019; 10(1): 16.     CrossRef
• Increasing Hospitalizations for DKA: A Need for Prevention Programs
  Priyathama Vellanki, Guillermo E. Umpierrez
  Diabetes Care.2018; 41(9): 1839.     CrossRef
• Guidelines and controversies in the management of diabetic ketoacidosis – A mini-review
  Tasnim Islam, Khalid Sherani, Salim Surani, Abhay Vakil
  World Journal of Diabetes.2018; 9(12): 226.     CrossRef
• Closing the Mortality Gap in Diabetic Ketoacidosis and Hyperosmolar Hyperglycemic State: Implications of a Clinical Decision Support App
  Saperstein Y, Park J, McFarlane SI
  International Journal of Clinical Endocrinology and Metabolism.2018; : 008.     CrossRef
• Incidence and prevalence of diabetic ketoacidosis (DKA) among adults with type 1 diabetes mellitus (T1D): a systematic literature review
  Soulmaz Fazeli Farsani, Kimberly Brodovicz, Nima Soleymanlou, Jan Marquard, Erika Wissinger, Brett A Maiese
  BMJ Open.2017; 7(7): e016587.     CrossRef

Citations

Citations to this article as recorded by  

• Performance of a preventive care programme for osteoporosis in primary care settings in Singapore during the COVID-19 pandemic
  Chin Kwang Chong, Wei Ting Chua, Susie Ling Yii Wong, Tat Yean Tham
  Proceedings of Singapore Healthcare.2024;[Epub]     CrossRef
• Real world fracture prediction of fracture risk assessment tool (FRAX), osteoporosis self-assessment tool for Asians (OSTA) and one-minute osteoporosis risk test: An 11-year longitudinal study
  Yueh-Hsuan Sheng, Tai-Yin Wu, Chen-Kun Liaw, Sheng-Huang Hsiao, Kuan-Liang Kuo, Ching-Yao Tsai
  Bone Reports.2024; 20: 101742.     CrossRef
• Assessment of Osteoporosis Awareness and Osteoporosis Risk Level of Patients Admitted to a University Hospital
  Turkan Pasali Kilit, Kevser Onbasi, Filiz Ozyigit
  Journal of Clinical Densitometry.2022; 25(4): 528.     CrossRef
• Current status and challenges in the management of osteoporosis among men in the Philippines
  Abraham C. Sianoya, Eric David B. Ornos, Jerico R. Santos, Ourlad Alzeus G. Tantengco, Cecilia A. Jimeno
  Archives of Osteoporosis.2022;[Epub]     CrossRef
• Bone Mineral Density Among Men and Women Aged 35 to 50 Years
  Martha A. Bass, Ankita Sharma, Vinayak K. Nahar, Stacy Chelf, Brittany Zeller, Linda Pham, M. Allison Ford
  Journal of Osteopathic Medicine.2019; 119(6): 357.     CrossRef
• Articles inEndocrinology and Metabolismin 2016
  Won-Young Lee
  Endocrinology and Metabolism.2017; 32(1): 62.     CrossRef
• A review on the performance of osteoporosis self-assessment tool for Asians in determining osteoporosis and fracture risk
  Kok-Yong Chin
  Postgraduate Medicine.2017; 129(7): 734.     CrossRef

Citations

Citations to this article as recorded by  

• How Reliable are Commercially Available Glypican4 ELISA Kits?
  Joseph P. Buhl, Antje Garten, Jürgen Kratzsch, Wieland Kiess, Melanie Penke
  Experimental and Clinical Endocrinology & Diabetes.2022; 130(02): 110.     CrossRef
• Serum glypican-4 is associated with the 10-year clinical outcome of patients with peripheral artery disease
  Axel Muendlein, Christine Heinzle, Andreas Leiherer, Kathrin Geiger, Eva Maria Brandtner, Stella Gaenger, Peter Fraunberger, Christoph H. Saely, Heinz Drexel
  International Journal of Cardiology.2022; 369: 54.     CrossRef
• Berberine activates the β-catenin/TCF4 signaling pathway by down-regulating miR-106b to promote GLP-1 production by intestinal L cells
  Jiao Wang, Li-Rui Wei, Yan-Ling Liu, Cheng-Zhi Ding, Feng Guo, Jiao Wang, Qian Qin, Feng-Jiao Huang, Ying Xin, Sheng-Nan Ma, Qiu-Ran Zhai, Shou-Jun Wang, Gui-Jun Qin
  European Journal of Pharmacology.2021; 911: 174482.     CrossRef
• Increased Glypican-4 Levels Are Associated with Obesity in Adolescents
  Huseyin Dag, Nevin Cetin Dag, Okan Dikker
  Iranian Journal of Pediatrics.2019;[Epub]     CrossRef
• Serum glypican 4 level in obese children and its relation to degree of obesity
  Chutima Leelalertlauw, Manassawee Korwutthikulrangsri, Pat Mahachoklertwattana, Suwannee Chanprasertyothin, Patcharin Khlairit, Sarunyu Pongratanakul, Preamrudee Poomthavorn
  Clinical Endocrinology.2017; 87(6): 689.     CrossRef
• Articles inEndocrinology and Metabolismin 2016
  Won-Young Lee
  Endocrinology and Metabolism.2017; 32(1): 62.     CrossRef
• Efficacy and Safety of Single‐ or Double‐Drug Antidiabetic Regimens in the Treatment of Type 2 Diabetes Mellitus: A Network Meta‐Analysis
  Xi‐Ling Yang, Mi‐Ma Duo‐Ji, Zi‐Wen Long
  Journal of Cellular Biochemistry.2017; 118(12): 4536.     CrossRef

Citations

Citations to this article as recorded by  

• Association Between CST3 Gene Polymorphisms and Large-Artery Atherosclerotic Stroke
  Yarong Ding, Zhe Xu, Yuesong Pan, Xia Meng, Xianglong Xiang, Hao Li, Liping Liu, Yongjun Wang
  Frontiers in Neurology.2021;[Epub]     CrossRef
• Long-term effects of various types of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on changes in glomerular filtration rate in Korea
  Seo Yeon Baik, Hyunah Kim, So Jung Yang, Tong Min Kim, Seung-Hwan Lee, Jae Hyoung Cho, Hyunyong Lee, Hyeon Woo Yim, Kun-Ho Yoon, Hun-Sung Kim
  Frontiers of Medicine.2019; 13(6): 713.     CrossRef
• Gender specific association of parathyroid hormone and vitamin D with metabolic syndrome in population with preserved renal function
  Min-Hee Kim, Jeongmin Lee, Jeonghoon Ha, Kwanhoon Jo, Dong-Jun Lim, Jung-Min Lee, Sang-Ah Chang, Moo-Il Kang, Bong Yun Cha
  Scientific Reports.2018;[Epub]     CrossRef
• PROBLEM OF THE ASSESMENT OF GLOMERULAR FILTRATION RATE IN OBESITY
  A. V. Smirnov, I. G. Kayukov, A. Sh. Rumyantsev
  Nephrology (Saint-Petersburg).2017; 21(2): 20.     CrossRef