Endocrinology and Metabolism

Case Report

A Case of Black Adrenocortical Adenoma Causing Cushing's Syndrome with Contralateral Nonfuncioning Adenoma.: Do Joon Park, Kyung Soo Park, Kyung Jae Nam, Sung Yeon Kim, Bo Yeon Cho, Hong Gyu Lee, Yeo Kyu Yoon, Seung Keun Oh; J Korean Endocr Soc. 1999;14(2):410-417. Published online January 1, 2001

Abstract PDF: We report herein the case of a 38-year-old woman with Cushings syndrome caused by bilateral adrenocortical adenomas. The adrenal tumor on the left side hypersecreted cortisol and no findings of cortisol hypersecretion from the adrenal tumor on the right side were observed on bilateral adrenal vein samplings. Both adrenal tumors were resected and histologically without any findings of nodular hyperplasia. The left adrenal tumor was histologically diagnosed as a so-called black adenoma. These data imply that the adrenal adenomas developed primarily from the adrenal gland itself, and that one of the tumors was well differentiated and secreted excess hormones, while the other remained in cell proliferation without hypersecretion.

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