Endocrinology and Metabolism

Review Article

Thyroid

August 9, 2021

The Role of Thyroid Hormone in the Regulation of Cerebellar Development

Sumiyasu Ishii, Izuki Amano, Noriyuki Koibuchi

Endocrinol Metab. 2021;36(4):703-716.

The proper organized expression of specific genes in time and space is responsible for the organogenesis of the central nervous system including the cerebellum. The epigenetic regulation of gene expression...

Review Article

Thyroid

August 11, 2021

Active Surveillance as an Effective Management Option for Low-Risk Papillary Thyroid Microcarcinoma

Min Ji Jeon, Won Gu Kim, Tae Yong Kim, et al.

Endocrinol Metab. 2021;36(4):717-724.

Active surveillance (AS) for low-risk papillary thyroid microcarcinoma (PTMC) has been accepted worldwide as safe and effective. Despite the growing acceptance of AS in the management of low-risk PTMCs, there...

Review Article

Thyroid

August 27, 2021

The Concept of Economic Evaluation and Its Application in Thyroid Cancer Research

Kyungsik Kim, Mijin Kim, Woojin Lim, et al.

Endocrinol Metab. 2021;36(4):725-736.

Economic evaluation is a type of comparative analysis between interventions in terms of both their resource use and health outcomes. Due to the good prognosis of thyroid cancer (TC), the...

Review Article

Diabetes, Obesity and Metabolism

August 10, 2021

Exercise/Resistance Training and Muscle Stem Cells

So-ichiro Fukada, Ayasa Nakamura

Endocrinol Metab. 2021;36(4):737-744.

Skeletal muscle has attracted attention as endocrine organ, because exercise-dependent cytokines called myokines/exerkines are released from skeletal muscle and are involved in systemic functions. While, local mechanical loading to skeletal...

Review Article

Diabetes, Obesity and Metabolism

August 27, 2021

Effects of Intermittent Fasting on the Circulating Levels and Circadian Rhythms of Hormones

Bo Hye Kim, Yena Joo, Min-Seon Kim, et al.

Endocrinol Metab. 2021;36(4):745-756.

Intermittent fasting has become an increasingly popular strategy in losing weight and associated reduction in obesity-related medical complications. Overwhelming studies support metabolic improvements from intermittent fasting in blood glucose levels,...

Original Article

Thyroid

August 27, 2021

Thyroid Hormone Profile and Its Prognostic Impact on the Coronavirus Disease 2019 in Korean Patients

Jiyeon Ahn, Min Kyung Lee, Jae Hyuk Lee, et al.

Endocrinol Metab. 2021;36(4):769-777.

Background: Data on the association between coronavirus disease 2019 (COVID-19) and thyroid have been reported, including overt thyrotoxicosis and suppression of thyroid function. We aimed to evaluate the thyroid hormone...

Original Article

Thyroid

August 10, 2021

The Positive Association between Subclinical Hypothyroidism and Newly-Diagnosed Hypertension Is More Explicit in Female Individuals Younger than 65

Xichang Wang, Haoyu Wang, Li Yan, et al.

Endocrinol Metab. 2021;36(4):778-789.

Background: Subclinical hypothyroidism (SCH) is the most common thyroid dysfunction, and its relationship with blood pressure (BP) has been controversial. The aim of the study was to analyze the association...

Original Article

Thyroid

August 11, 2021

Association between Iodine Intake, Thyroid Function, and Papillary Thyroid Cancer: A Case-Control Study

Kyungsik Kim, Sun Wook Cho, Young Joo Park, et al.

Endocrinol Metab. 2021;36(4):790-799.

Background: This study aimed to assess the effects of iodine intake, thyroid function, and their combined effect on the risk of papillary thyroid cancer (PTC) and papillary thyroid microcarcinoma (PTMC). Methods:...

Original Article

Diabetes, Obesity and Metabolism

August 20, 2021

High Fibrosis-4 Index Is Related with Worse Clinical Outcome in Patients with Coronavirus Disease 2019 and Diabetes Mellitus: A Multicenter Observational Study

Sung-Woo Kim, Jae-Han Jeon, Jun Sung Moon, et al.

Endocrinol Metab. 2021;36(4):800-809.

Background: Based on recent evidence on the importance of the presence of diabetes mellitus (DM) and fibrosis-4 (FIB-4) index in coronavirus disease 2019 (COVID-19) mortality, we analyzed whether these factors...

Original Article

Diabetes, Obesity and Metabolism

August 27, 2021

Tetrahydrocurcumin Ameliorates Kidney Injury and High Systolic Blood Pressure in High-Fat Diet-Induced Type 2 Diabetic Mice

Weerapon Sangartit, Kyung Bong Ha, Eun Soo Lee, et al.

Endocrinol Metab. 2021;36(4):810-822.

Background: Activation of the intrarenal renin-angiotensin system (RAS) is implicated in the pathogenesis of kidney injury and hypertension. We aimed to investigate the protective effect of tetrahydrocurcumin (THU) on intrarenal...

Original Article

Diabetes, Obesity and Metabolism

August 27, 2021

Non-Laboratory-Based Simple Screening Model for Nonalcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Developed Using Multi-Center Cohorts

Jiwon Kim, Minyoung Lee, Soo Yeon Kim, et al.

Endocrinol Metab. 2021;36(4):823-834.

Background: Nonalcoholic fatty liver disease (NAFLD) is the most prevalent cause of chronic liver disease worldwide. Type 2 diabetes mellitus (T2DM) is a risk factor that accelerates NAFLD progression, leading...

Original Article

Diabetes, Obesity and Metabolism

August 27, 2021

Lower High-Density Lipoprotein Cholesterol Concentration Is Independently Associated with Greater Future Accumulation of Intra-Abdominal Fat

Sun Ok Song, You-Cheol Hwang, Han Uk Ryu, et al.

Endocrinol Metab. 2021;36(4):835-844.

Background: Both intra-abdominal fat (IAF) and high-density lipoprotein cholesterol (HDL-C) are known to be associated with cardiometabolic health. We evaluated whether the accumulation of computed tomography (CT)-measured IAF over 5...

Original Article

Diabetes, Obesity and Metabolism

August 27, 2021

Increased Risk of Nonalcoholic Fatty Liver Disease in Individuals with High Weight Variability

Inha Jung, Dae-Jeong Koo, Mi Yeon Lee, et al.

Endocrinol Metab. 2021;36(4):845-854.

Background: Weight loss through lifestyle modification is recommended for patients with nonalcoholic fatty liver disease (NAFLD). Recent studies have suggested that repeated loss and gain of weight is associated with...

Original Article

Diabetes, Obesity and Metabolism

August 11, 2021

Differences in Abdominal Body Composition According to Glycemic Status: An Inverse Probability Treatment Weighting Analysis

Seungbong Han, Young-Jee Jeon, Gyung-Min Park, et al.

Endocrinol Metab. 2021;36(4):855-864.

Background: Several studies have reported that abdominal fat and muscle changes occur in diabetic patients. However, there are few studies about such changes among prediabetic patients. In this study, we...

Original Article

Adrenal Gland

July 30, 2021

Aldosterone Inhibits In Vitro Myogenesis by Increasing Intracellular Oxidative Stress via Mineralocorticoid Receptor

Jin Young Lee, Da Ae Kim, Eunah Choi, et al.

Endocrinol Metab. 2021;36(4):865-874.

Background: Despite clinical evidence indicating poor muscle health in subjects with primary aldosteronism (PA), it is still unclear whether the role of aldosterone in muscle metabolism is direct or mediated...

Original Article

Adrenal Gland

August 11, 2021

Contralateral Suppression at Adrenal Venous Sampling Is Associated with Renal Impairment Following Adrenalectomy for Unilateral Primary Aldosteronism

Ye Seul Yang, Seung Hun Lee, Jung Hee Kim, et al.

Endocrinol Metab. 2021;36(4):875-884.

Background: Adrenal venous sampling (AVS) is performed to distinguish the subtype of primary aldosteronism (PA). The clinical implication of contralateral suppression (CS; aldosterone/cortisolnondominant

Original Article

Adrenal Gland

August 10, 2021

Lipid Profiles in Primary Aldosteronism Compared with Essential Hypertension: Propensity-Score Matching Study

Sun Joon Moon, Han Na Jang, Jung Hee Kim, et al.

Endocrinol Metab. 2021;36(4):885-894.

Background: There has been controversy regarding the association between primary aldosteronism (PA) and dyslipidemia and few studies considered the effects of diabetes and renal function on lipid metabolism. We analyzed...

Original Article

Bone Metabolism

August 9, 2021

Comparison of the Effects of Various Antidiabetic Medication on Bone Mineral Density in Patients with Type 2 Diabetes Mellitus

Jeonghoon Ha, Yejee Lim, Mee Kyoung Kim, et al.

Endocrinol Metab. 2021;36(4):895-903.

Background: Prospective comparative studies on the effects of various antidiabetic agents on bone metabolism are limited. This study aimed to assess changes in bone mass and biochemical bone markers in...

Current Issue: Volume 36(4); Aug 2021

How Can We Adopt the Glucose Tolerance Test to Facilitate Predicting Pregnancy Outcome in Gestational Diabetes Mellitus? Kyeong Jin Kim, Nam Hoon Kim, Jimi Choi, et al. [Epub ahead of print] Original Article Oct 15, 2021 PDF	Role of TRPV4 Channel in Human White Adipocytes Metabolic Activity Julio C. Sánchez, Aníbal Valencia-Vásquez, Andrés M. García [Epub ahead of print] Original Article Oct 14, 2021 PDF
Lobeglitazone, A Peroxisome Proliferator-Activated Receptor-Gamma Agonist, Inhibits Papillary Thyroid Cancer Cell Migration and Invasion by Suppressing p38 MAPK Signaling Pathway Jun-Qing Jin, Jeong-Sun Han, Jeonghoon Ha, et al. [Epub ahead of print] Original Article Oct 14, 2021 PDF	The Effects of Glucose Lowering Agents on the Secondary Prevention of Coronary Artery Disease in Patients with Type 2 Diabetes Inha Jung, Hyemi Kwon, Se Eun Park, et al. [Epub ahead of print] Original Article Oct 14, 2021 PDF
T4+T3 Combination Therapy: An Unsolved Problem of Increasing Magnitude and Complexity Wilmar M. Wiersinga [Epub ahead of print] Review Article Sep 30, 2021 PDF	Association of Protein Z with Prediabetes and Type 2 Diabetes (Endocrinol Metab 2021;36:637-46, Yun-Ui Bae et al.) Ji Hong You, Yun-Ui Bae, Ho Chan Cho [Epub ahead of print] Response Sep 16, 2021 PDF
Association of Protein Z with Prediabetes and Type 2 Diabetes (Endocrinol Metab 2021;36:637-46, Yun-Ui Bae et al.) Tiffany Pascreau, Maia Tchikviladze, Emilie Jolly, et al. [Epub ahead of print] Letter Aug 25, 2021 Full text PubReader ePub PDF

Endocrinology
and Metabolism

Print ISSN: 2093-596X
Online ISSN: 2093-5978

7,383	WD40-Repeat Proteins in Ciliopathies and Congenital Disorders of Endocrine System
6,278	Encountering COVID-19 as Endocrinologists
6,248	Protein Expression of Cyclin B1, Transferrin Receptor, and Fibronectin Is Correlated with the Prognosis of Adrenal Cortical Carcinoma
5,406	Tumor Cells and Cancer-Associated Fibroblasts: A Synergistic Crosstalk to Promote Thyroid Cancer
5,342	Dipeptidyl Peptidase-4 Inhibitors and COVID-19-Related Deaths among Patients with Type 2 Diabetes Mellitus: A Meta-Analysis of Observational Studies

Cited By 33	Long-Term Outcomes Following Thermal Ablation of Benign Thyroid Nodules as an Alternative to Surgery: The Importance of Controlling Regrowth
Cited By 31	Recent Progress on Branched-Chain Amino Acids in Obesity, Diabetes, and Beyond
Cited By 26	Nonalcoholic Fatty Liver Disease and Diabetes: An Epidemiological Perspective
Cited By 23	Graves' Disease: Can It Be Cured?
Cited By 22	Triglyceride Glucose Index Is Superior to the Homeostasis Model Assessment of Insulin Resistance for Predicting Nonalcoholic Fatty Liver Disease in Korean Adults