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Review Article

June 23, 2020


Encountering COVID-19 as Endocrinologists
Eun-Jung Rhee, Jung Hee Kim, Sun Joon Moon, et al.
Endocrinol Metab. 2020;35(2):197-205.
The world is entering an era of disaster and chaos due to coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2. Since its first emergence...

Review Article

June 24, 2020


Precision Therapy in Acromegaly Caused by Pituitary Tumors: How Close Is It to Reality?
Cheol Ryong Ku, Vladimir Melnikov, Zhaoyun Zhang, et al.
Endocrinol Metab. 2020;35(2):206-216.

Acromegaly presents with an enigmatic range of symptoms and comorbidities caused by chronic and progressive growth hormone elevations, commonly due to endocrinologic hypersecretion from a pituitary gland tumor. Comprehensive national...

Review Article

June 24, 2020


Effects of Cardiovascular Risk Factor Variability on Health Outcomes
Seung-Hwan Lee, Mee Kyoung Kim, Eun-Jung Rhee
Endocrinol Metab. 2020;35(2):217-226.

Innumerable studies have suggested “the lower, the better” for cardiovascular risk factors, such as body weight, lipid profile, blood pressure, and blood glucose, in terms of health outcomes. However, excessively...

Review Article

June 24, 2020


Amino Acid Transporters as Potential Therapeutic Targets in Thyroid Cancer
Keisuke Enomoto, Muneki Hotomi
Endocrinol Metab. 2020;35(2):227-236.

Thyroid cancer cells have a high amino acid demand for proliferation, invasion, and metastasis. Amino acids are taken up by thyroid cancer cells, both thyroid follicular cell and thyroid parafollicular...

Review Article

June 24, 2020


Epidemiology of Functioning Pituitary Adenomas
Sang Ouk Chin
Endocrinol Metab. 2020;35(2):237-242.

Pituitary adenomas (PAs) are defined as benign monoclonal tumors in the pituitary gland that cause symptoms due to either hormonal hypersecretion or a space-occupying effect, and are classified as functioning...

Review Article

June 24, 2020


Noninvasive Evaluation of Nonalcoholic Fatty Liver Disease
Dae Ho Lee
Endocrinol Metab. 2020;35(2):243-259.

Nonalcoholic fatty liver disease (NAFLD) is the most prevalent liver diseases and can progress to advanced fibrosis and end-stage liver disease. Thus, intensive research has been performed to develop noninvasive...

Review Article

June 24, 2020


Recent Updates on Vascular Complications in Patients with Type 2 Diabetes Mellitus
Chan-Hee Jung, Ji-Oh Mok
Endocrinol Metab. 2020;35(2):260-271.

It is well known that patients with type 2 diabetes mellitus (T2DM) are at an increased risk of morbidity and mortality from atherosclerotic cardiovascular (CV) complications. Previously, the concept that...

Original Article

Clinical Study

June 24, 2020


Fasting and Postprandial Hyperglycemia: Their Predictors and Contributions to Overall Hyperglycemia in Korean Patients with Type 2 Diabetes
Jaecheol Moon, Ji Young Kim, Soyeon Yoo, et al.
Endocrinol Metab. 2020;35(2):290-297.

Background: This study aimed to identify factors that affect fasting hyperglycemia (FHG) and postprandial hyperglycemia (PPG) and their contributions to overall hyperglycemia in Korean patients with type 2 diabetes mellitus...

Original Article

Clinical Study

June 24, 2020


Effects of a Portfolio-Mediterranean Diet and a Mediterranean Diet with or without a Sterol-Enriched Yogurt in Individuals with Hypercholesterolemia
Yvelise Ferro, Elisa Mazza, Mariantonietta Salvati, et al.
Endocrinol Metab. 2020;35(2):298-307.

Background: A growing number of functional foods have been proposed to reduce cholesterol levels and the Portfolio Diet, which includes a combination of plant sterols, fibres, nuts, and soy protein,...

Original Article

Clinical Study

June 24, 2020


Subclinical Hypothyroidism Affects the Long-Term Outcomes of Patients Who Undergo Coronary Artery Bypass Grafting Surgery but Not Heart Valve Surgery
Hana Kim, Sung Hye Kong, Jae Hoon Moon, et al.
Endocrinol Metab. 2020;35(2):308-318.

Background: The aim of this study was to determine the associations between subclinical hypothyroidism (SCH) and long-term cardiovascular outcomes after coronary artery bypass grafting (CABG) or heart valve surgery (HVS). Methods:...

Original Article

Clinical Study

June 24, 2020


Relationships between Thigh and Waist Circumference, Hemoglobin Glycation Index, and Carotid Plaque in Patients with Type 2 Diabetes
Myung Ki Yoon, Jun Goo Kang, Seong Jin Lee, et al.
Endocrinol Metab. 2020;35(2):319-328.

Background: This study investigated the relationships of thigh and waist circumference with the hemoglobin glycation index (HGI) and carotid atherosclerosis in patients with type 2 diabetes. Methods: This observational study included...

Original Article

Clinical Study

June 24, 2020


Glycemic Efficacy and Metabolic Consequences of an Empagliflozin Add-on versus Conventional Dose-Increasing Strategy in Patients with Type 2 Diabetes Inadequately Controlled by Metformin and Sulfonylurea
Yujin Shin, Ji Hye Moon, Ho Jun Chin, et al.
Endocrinol Metab. 2020;35(2):329-338.

Background: We assessed the glucose-lowering efficacy of adding empagliflozin versus dose escalating existing medications in patients with uncontrolled type 2 diabetes (T2D). Methods: This was a 6-month retrospective case-control study in...

Original Article

Clinical Study

June 24, 2020


Long-Term Results of Thermal Ablation of Benign Thyroid Nodules: A Systematic Review and Meta-Analysis
Se Jin Cho, Jung Hwan Baek, Sae Rom Chung, et al.
Endocrinol Metab. 2020;35(2):339-350.

Background: Ultrasound-guided thermal ablations have become one of the main options for treating benign thyroid nodules. To determine efficacy of thermal ablation of benign thyroid nodules, we performed a meta-analysis...

Original Article

Clinical Study

June 24, 2020


Apolipoprotein B Levels Predict Future Development of Hypertension Independent of Visceral Adiposity and Insulin Sensitivity
Seung Jin Han, Wilfred Y. Fujimoto, Steven E. Kahn, et al.
Endocrinol Metab. 2020;35(2):351-358.

Background: High plasma apolipoprotein B (apoB) levels have been shown to be associated with hypertension, central obesity, and insulin resistance in cross-sectional research. However, it is unclear whether apoB levels...

Original Article

Clinical Study

June 24, 2020


Low Predictive Value of FRAX Adjusted by Trabecular Bone Score for Osteoporotic Fractures in Korean Women: A Community-Based Cohort Study
Hana Kim, Jung Hee Kim, Min Joo Kim, et al.
Endocrinol Metab. 2020;35(2):359-366.

Background: The value of the Fracture Risk Assessment Tool (FRAX) and the trabecular bone score (TBS) for assessing osteoporotic fracture risk has not been fully elucidated in Koreans. We conducted...

Original Article

Clinical Study

June 24, 2020


Achievement of LDL-C Targets Defined by ESC/EAS (2011) Guidelines in Risk-Stratified Korean Patients with Dyslipidemia Receiving Lipid-Modifying Treatments
Ye Seul Yang, Seo Young Lee, Jung-Sun Kim, et al.
Endocrinol Metab. 2020;35(2):367-376.

Background: This study assessed the proportion of risk-stratified Korean patients with dyslipidemia achieving their low-density lipoprotein cholesterol (LDL-C) targets as defined by the European Society of Cardiology/European Atherosclerosis Society (ESC/EAS)...

Original Article

Clinical Study

June 24, 2020


Consistency of the Glycation Gap with the Hemoglobin Glycation Index Derived from a Continuous Glucose Monitoring System
Han Na Joung, Hyuk-Sang Kwon, Ki-Hyun Baek, et al.
Endocrinol Metab. 2020;35(2):377-383.

Background: Discordances between glycated hemoglobin (HbA1c) levels and glycemic control are common in clinical practice. We aimed to investigate the consistency of the glycation gap with the hemoglobin glycation index...

Original Article

Clinical Study

June 24, 2020


Gemigliptin Inhibits Interleukin-1β–Induced Endothelial-Mesenchymal Transition via Canonical-Bone Morphogenetic Protein Pathway
Oak-Kee Hong, Seong-Su Lee, Soon Jib Yoo, et al.
Endocrinol Metab. 2020;35(2):384-395.

Background: Endothelial-to-mesenchymal transition (EndMT) contributes to inflammatory conditions inducing conversion of endothelial cells (ECs) into activated fibroblasts, promoting fibrotic diseases. Pro-inflammatory cytokine is the most potent inducer of EndMT. We...

Original Article

Clinical Study

June 24, 2020


Serum Adiponectin and Progranulin Level in Patients with Benign Thyroid Nodule or Papillary Thyroid Cancer
Hyemi Kwon, Se Eun Park, Ji-Sup Yun, et al.
Endocrinol Metab. 2020;35(2):396-406.

Background: Obesity is associated with thyroid cancer risk. Adiponectin has insulin-sensitizing and anti-inflammatory effects, while progranulin is associated with inflammation and tumorigenesis. We investigated serum adiponectin and progranulin levels in...

Original Article

Clinical Study

June 24, 2020


Effectiveness of Injecting Cold 5% Dextrose into Patients with Nerve Damage Symptoms during Thyroid Radiofrequency Ablation
Min Kyoung Lee, Jung Hwan Baek, Sae Rom Chung, et al.
Endocrinol Metab. 2020;35(2):407-415.

Background: Although radiofrequency ablation (RFA) is a safe treatment for thyroid tumors, nerve damage is a frequent complication. A previous retrospective study suggested that an injection of cold 5% dextrose...

Original Article

Clinical Study

June 24, 2020


Association of Body Mass Index with the Risk of Incident Type 2 Diabetes, Cardiovascular Disease, and All-Cause Mortality: A Community-Based Prospective Study
Ji Cheol Bae, Nam H. Cho, Jae Hyeon Kim, et al.
Endocrinol Metab. 2020;35(2):416-424.

Background: Type 2 diabetes and cardiovascular disease (CVD) are the most important sequelae of obesity and the leading cause of death. We evaluated the association between body mass index (BMI)...

Original Article

Clinical Study

June 24, 2020


Effect of Lactobacillus sakei, a Probiotic Derived from Kimchi, on Body Fat in Koreans with Obesity: A Randomized Controlled Study
Soo Lim, Ji Hye Moon, Chol Min Shin, et al.
Endocrinol Metab. 2020;35(2):425-434.

Background: The increased prevalence of obesity has led to increases in the prevalence of chronic diseases worldwide. There is interest whether probiotics have an effect on obesity, but the effectiveness...

Original Article

Clinical Study

June 24, 2020


Development and Validation of a Risk Scoring System Derived from Meta-Analyses of Papillary Thyroid Cancer
Sunghwan Suh, Tae Sik Goh, Yun Hak Kim, et al.
Endocrinol Metab. 2020;35(2):435-442.

Background: The aim of this study was to develop a scoring system to stratify the risk of papillary thyroid cancer (PTC) and to select the proper management. Methods: We performed a...

Original Article

Clinical Study

June 24, 2020


Mechanisms of the Impact of Hashimoto Thyroiditis on Papillary Thyroid Carcinoma Progression: Relationship with the Tumor Immune Microenvironment
Oksana Sulaieva, Olena Chernenko, Oleksiy Selesnov, et al.
Endocrinol Metab. 2020;35(2):443-455.

Background: The relationship between Hashimoto thyroiditis (HT) and papillary thyroid carcinoma (PTC) remains uncertain. We assessed the impact of HT on the tumor immune microenvironment (TIME) in PTC. Methods: Thirty patients...

Original Article

Endocrine Research

June 24, 2020


Transformation of Mature Osteoblasts into Bone Lining Cells and RNA Sequencing-Based Transcriptome Profiling of Mouse Bone during Mechanical Unloading
A Ram Hong, Kwangsoo Kim, Ji Yeon Lee, et al.
Endocrinol Metab. 2020;35(2):456-469.

Background: We investigated RNA sequencing-based transcriptome profiling and the transformation of mature osteoblasts into bone lining cells (BLCs) through a lineage tracing study to better understand the effect of mechanical...

Original Article

Endocrine Research

June 24, 2020


Serotonin Regulates De Novo Lipogenesis in Adipose Tissues through Serotonin Receptor 2A
Ko Eun Shong, Chang-Myung Oh, Jun Namkung, et al.
Endocrinol Metab. 2020;35(2):470-479.

Background: Obesity is defined as excessive fat mass and is a major cause of many chronic diseases such as diabetes, cardiovascular disease, and cancer. Increasing energy expenditure and regulating adipose...
Current Issue
Volume 35(2); Jun 2020
Association of Adipokines with Development and Progression of Nonalcoholic Fatty Liver Disease
Chrysoula Boutari, Nikolaos Perakakis, Christos Socrates Mantzoros
Endocrinol Metab. 2018;33(1):33-43.

Review Article

Mar 21, 2018
Evidence of the Possible Harm of Endocrine-Disrupting Chemicals in Humans: Ongoing Debates and Key Issues
Duk-Hee Lee
Endocrinol Metab. 2018;33(1):44-52.

Review Article

Mar 21, 2018
Genome-Wide Association Studies of Autoimmune Thyroid Diseases, Thyroid Function, and Thyroid Cancer
Yul Hwangbo, Young Joo Park
Endocrinol Metab. 2018;33(2):175-184.

Review Article

Jun 21, 2018
Effects of Resistance Exercise on Bone Health
A Ram Hong, Sang Wan Kim
Endocrinol Metab. 2018;33(4):435-444.

Review Article

Nov 30, 2018
Graves' Disease: Can It Be Cured?
Wilmar M. Wiersinga
Endocrinol Metab. 2019;34(1):29-38.

Review Article

Mar 21, 2019
Recent Updates on the Diagnosis and Management of Cushing's Syndrome
Lynnette K. Nieman
Endocrinol Metab. 2018;33(2):139-146.

Review Article

Jun 21, 2018
Prognosis of Differentiated Thyroid Carcinoma with Initial Distant Metastasis: A Multicenter Study in Korea
Hosu Kim, Hye In Kim, Sun Wook Kim, et al.
Endocrinol Metab. 2018;33(2):287-295.

Original Article

Jun 21, 2018
Management of Low-Risk Papillary Thyroid Cancer
Nicole M. Iñiguez-Ariza, Juan P. Brito
Endocrinol Metab. 2018;33(2):185-194.

Review Article

Jun 21, 2018
Genetic Polymorphism Predisposing to Differentiated Thyroid Cancer: A Review of Major Findings of the Genome-Wide Association Studies
Vladimir A. Saenko, Tatiana I. Rogounovitch
Endocrinol Metab. 2018;33(2):164-174.

Review Article

Jun 21, 2018
Study Protocol of Multicenter Prospective Cohort Study of Active Surveillance on Papillary Thyroid Microcarcinoma (MAeSTro)
Jae Hoon Moon, Ji-hoon Kim, Eun Kyung Lee, et al.
Endocrinol Metab. 2018;33(2):278-286.

Original Article

Jun 21, 2018
Combined Effects of Baicalein and Docetaxel on Apoptosis in 8505c Anaplastic Thyroid Cancer Cells via Downregulation of the ERK and Akt/mTOR Pathways
Chan Ho Park, Se Eun Han, Il Seong Nam-Goong, et al.
Endocrinol Metab. 2018;33(1):121-132.

Original Article

Mar 21, 2018
Long-Term Outcomes Following Thermal Ablation of Benign Thyroid Nodules as an Alternative to Surgery: The Importance of Controlling Regrowth
Jung Suk Sim, Jung Hwan Baek
Endocrinol Metab. 2019;34(2):117-123.

Review Article

Jun 24, 2019
Associations between Hashimoto Thyroiditis and Clinical Outcomes of Papillary Thyroid Cancer: A Meta-Analysis of Observational Studies
Shinje Moon, Hye Soo Chung, Jae Myung Yu, et al.
Endocrinol Metab. 2018;33(4):473-484.

Original Article

Nov 30, 2018
Recent Topics in Fibrodysplasia Ossificans Progressiva
Takenobu Katagiri, Sho Tsukamoto, Yutaka Nakachi, et al.
Endocrinol Metab. 2018;33(3):331-338.

Review Article

Sep 18, 2018
Effect of Dapagliflozin on Alanine Aminotransferase Improvement in Type 2 Diabetes Mellitus with Non-alcoholic Fatty Liver Disease
Dug-Hyun Choi, Chan-Hee Jung, Ji-Oh Mok, et al.
Endocrinol Metab. 2018;33(3):387-394.

Original Article

Clinical Study

Sep 18, 2018
Latent Autoimmune Diabetes in Adults: Current Status and New Horizons
Paolo Pozzilli, Silvia Pieralice
Endocrinol Metab. 2018;33(2):147-159.

Review Article

Jun 21, 2018
Skeletal Fragility in Type 2 Diabetes Mellitus
Jakob Starup-Linde, Katrine Hygum, Bente Lomholt Langdahl
Endocrinol Metab. 2018;33(3):339-351.

Review Article

Sep 18, 2018
Prevalence and Annual Incidence of Thyroid Disease in Korea from 2006 to 2015: A Nationwide Population-Based Cohort Study
Hyemi Kwon, Jin-hyung Jung, Kyung-Do Han, et al.
Endocrinol Metab. 2018;33(2):260-267.

Original Article

Jun 21, 2018
Comparison of Immunohistochemistry and Direct Sanger Sequencing for Detection of the BRAFV600E Mutation in Thyroid Neoplasm
Hye-Seon Oh, Hyemi Kwon, Suyeon Park, et al.
Endocrinol Metab. 2018;33(1):62-69.

Original Article

Jan 30, 2018
Implications of Mitochondrial Unfolded Protein Response and Mitokines: A Perspective on Fatty Liver Diseases
Hyon-Seung Yi
Endocrinol Metab. 2019;34(1):39-46.

Review Article

Mar 21, 2019
Pathophysiology of Type 2 Diabetes in Koreans
Soo Heon Kwak, Kyong Soo Park
Endocrinol Metab. 2018;33(1):9-16.

Review Article

Mar 21, 2018
Nonalcoholic Fatty Liver Disease and Diabetes: An Epidemiological Perspective
Eun-Jung Rhee
Endocrinol Metab. 2019;34(3):226-233.

Review Article

Sep 26, 2019
Deficiency of Sphingosine-1-Phosphate Reduces the Expression of Prohibitin and Causes β-Cell Impairment via Mitochondrial Dysregulation
Seok-Woo Hong, Jinmi Lee, Hyemi Kwon, et al.
Endocrinol Metab. 2018;33(3):403-412.

Original Article

Endocrine Research

Sep 18, 2018
Comparison of the Effects of Ezetimibe-Statin Combination Therapy on Major Adverse Cardiovascular Events in Patients with and without Diabetes: A Meta-Analysis
Namki Hong, Yong-ho Lee, Kenichi Tsujita, et al.
Endocrinol Metab. 2018;33(2):219-227.

Original Article

May 4, 2018
Bone Health in Adrenal Disorders
Beom-Jun Kim, Seung Hun Lee, Jung-Min Koh
Endocrinol Metab. 2018;33(1):1-8.

Namgok Lecture 2017

Mar 21, 2018
Pioglitazone Attenuates Palmitate-Induced Inflammation and Endoplasmic Reticulum Stress in Pancreatic β-Cells
Seok-Woo Hong, Jinmi Lee, Jung Hwan Cho, et al.
Endocrinol Metab. 2018;33(1):105-113.

Original Article

Mar 21, 2018
A Comparison of Ultrasound-Guided Fine Needle Aspiration versus Core Needle Biopsy for Thyroid Nodules: Pain, Tolerability, and Complications
Eun Ji Jeong, Sae Rom Chung, Jung Hwan Baek, et al.
Endocrinol Metab. 2018;33(1):114-120.

Original Article

Mar 21, 2018
Evolution of Diabetes Care in Hong Kong: From the Hong Kong Diabetes Register to JADE-PEARL Program to RAMP and PEP Program
Ivy H.Y. Ng, Kitty K.T. Cheung, Tiffany T.L. Yau, et al.
Endocrinol Metab. 2018;33(1):17-32.

Review Article

Mar 21, 2018
Effects of Dipeptidyl Peptidase-4 Inhibitors on Renal Outcomes in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis
Jae Hyun Bae, Sunhee Kim, Eun-Gee Park, et al.
Endocrinol Metab. 2019;34(1):80-92.

Original Article

Mar 21, 2019
Primary Aldosteronism and Cerebrovascular Diseases
Zheng-Wei Chen, Chi-Sheng Hung, Vin-Cent Wu, et al.
Endocrinol Metab. 2018;33(4):429-434.

Review Article

Nov 30, 2018

Endocrinology
and Metabolism

Print ISSN: 2093-596X
Online ISSN: 2093-5978

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