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Review Article

August 20, 2020


Metabolically Healthy and Unhealthy Normal Weight and Obesity
Norbert Stefan
Endocrinol Metab. 2020;35(3):487-493.

Increased fat mass is an established risk factor for the cardiometabolic diseases type 2 diabetes and cardiovascular disease (CVD) and is associated with increased risk of all-cause and CVD mortality....

Review Article

September 8, 2020


WD40-Repeat Proteins in Ciliopathies and Congenital Disorders of Endocrine System
Yeonjoo Kim, Soo-Hyun Kim
Endocrinol Metab. 2020;35(3):494-506.

WD40-repeat (WDR)-containing proteins constitute an evolutionarily conserved large protein family with a broad range of biological functions. In human proteome, WDR makes up one of the most abundant protein-protein interaction...

Review Article

September 22, 2020


Systems Biology: A Multi-Omics Integration Approach to Metabolism and the Microbiome
Jang Won Son, Saeed Shoaie, Sunjae Lee
Endocrinol Metab. 2020;35(3):507-514.

The complex and dynamic nature of human physiology, as exemplified by metabolism, has often been overlooked due to the lack of quantitative and systems approaches. Recently, systems biology approaches have...

Review Article

September 22, 2020


Mechanisms of TERT Reactivation and Its Interaction with BRAFV600E
Young Shin Song, Young Joo Park
Endocrinol Metab. 2020;35(3):515-525.

The telomerase reverse transcriptase (TERT) gene, which is repressed in most differentiated human cells, can be reactivated by somatic TERT alterations and epigenetic modulations. Moreover, the recruitment, accessibility, and binding...

Review Article

September 22, 2020


Current National and International Guidelines for the Management of Male Hypogonadism: Helping Clinicians to Navigate Variation in Diagnostic Criteria and Treatment Recommendations
Ahmed Al-Sharefi, Richard Quinton
Endocrinol Metab. 2020;35(3):526-540.

Male hypogonadism—rebadged by some as testosterone deficiency syndrome—is a clinical and biochemical diagnosis of increasing worldwide interest. Organic male hypogonadism—usually permanent—is well-established, but aging men may also exhibit lower serum...

Review Article

September 22, 2020


Lessons from Use of Continuous Glucose Monitoring Systems in Digital Healthcare
Hun-Sung Kim, Kun-Ho Yoon
Endocrinol Metab. 2020;35(3):541-548.

We live in a digital world where a variety of wearable medical devices are available. These technologies enable us to measure our health in our daily lives. It is increasingly...

Original Article

Clinical Study

July 22, 2020


The Prevalence and Risk of Type 2 Diabetes in Adults with Disabilities in Korea
Inha Jung, Hyemi Kwon, Se Eun Park, et al.
Endocrinol Metab. 2020;35(3):552-561.

Background: People with disabilities are at risk of secondary conditions such as diabetes. The aim of this study was to evaluate the prevalence and risk of type 2 diabetes in...

Original Article

Clinical Study

September 22, 2020


Effects of Systemic Glucocorticoid Use on Fracture Risk: A Population-Based Study
Ji Weon Koh, Junkang Kim, Hyemin Cho, et al.
Endocrinol Metab. 2020;35(3):562-570.

Background: Long-term glucocorticoid use increases fracture risk by reducing bone mass. This study evaluated the relationship between hip and vertebral fractures and the total amount of systematic glucocorticoid use. Methods: We...

Original Article

Clinical Study

September 22, 2020


A Phase II Multi-Center, Non-Randomized, Parallel Group, Non-Inferiority Study to Compare the Efficacy of No Radioactive Iodine Remnant Ablation to Remnant Ablation Treatment in Low- to Intermediate-Risk of Papillary Thyroid Cancer: The MOREthyroid Trial Protocol
Eun Kyung Lee, You Jin Lee, Young Joo Park, et al.
Endocrinol Metab. 2020;35(3):571-577.

Background: Radioactive iodine (RAI) remnant ablation is recommended in patients with papillary thyroid cancer (PTC) and extrathyroidal extension or central lymph node metastasis. However, there exists little evidence about the...

Original Article

Clinical Study

September 22, 2020


Relationship of Sarcopenia with Microcirculation Measured by Skin Perfusion Pressure in Patients with Type 2 Diabetes
Chan-Hee Jung, Yoon Young Cho, Dughyun Choi, et al.
Endocrinol Metab. 2020;35(3):578-586.

Background: Few studies have examined the relationship of sarcopenia with the microcirculation. The current study investigated the relationship of sarcopenia with microcirculatory function, as assessed by skin perfusion pressure (SPP),...

Original Article

Clinical Study

September 22, 2020


Vandetanib for the Management of Advanced Medullary Thyroid Cancer: A Real-World Multicenter Experience
Mijin Kim, Jee Hee Yoon, Jonghwa Ahn, et al.
Endocrinol Metab. 2020;35(3):587-594.

Background: Vandetanib is the most widely used tyrosine kinase inhibitor for the treatment of patients with advanced medullary thyroid cancer (MTC). However, only limited data regarding its use outside clinical...

Original Article

Clinical Study

August 26, 2020


Fasting Plasma Glucose Level Independently Predicts the Mortality of Patients with Coronavirus Disease 2019 Infection: A Multicenter, Retrospective Cohort Study
Min Cheol Chang, Jong-Moon Hwang, Jae-Han Jeon, et al.
Endocrinol Metab. 2020;35(3):595-601.

Background: Coronavirus disease 2019 (COVID-19) has become a global pandemic, which prompts a consensus for the necessity to seek risk factors for this critical disease. Risk factors affecting mortality of...

Original Article

Clinical Study

September 22, 2020


Clinical Outcomes of N1b Papillary Thyroid Cancer Patients Treated with Two Different Doses of Radioiodine Ablation Therapy
Meihua Jin, Jonghwa Ahn, Yu-Mi Lee, et al.
Endocrinol Metab. 2020;35(3):602-609.

Background: The optimal dose of radioactive iodine (RAI) therapy for N1b papillary thyroid carcinoma (PTC) is controversial. We evaluated the clinical outcome of N1b PTC patients treated with either 100...

Original Article

Clinical Study

September 22, 2020


Serum Transferrin Predicts New-Onset Type 2 Diabetes in Koreans: A 4-Year Retrospective Longitudinal Study
Jong Dai Kim, Dong-Mee Lim, Keun-Young Park, et al.
Endocrinol Metab. 2020;35(3):610-617.

Background: It is well known that high serum ferritin, a marker of iron storage, predicts incident type 2 diabetes. Limited information is available on the association between transferrin, another marker...

Original Article

Clinical Study

September 22, 2020


Clinical Implication of World Health Organization Classification in Patients with Follicular Thyroid Carcinoma in South Korea: A Multicenter Cohort Study
Meihua Jin, Eun Sook Kim, Bo Hyun Kim, et al.
Endocrinol Metab. 2020;35(3):618-627.

Background: The study aimed to compare the prognostic value of the 4th edition of World Health Organization classification (WHO-2017) with the previous WHO classification (WHO-2004) for follicular thyroid carcinoma (FTC). Methods:...

Original Article

Clinical Study

September 22, 2020


Stimulated Salivary Cortisol as a Noninvasive Diagnostic Tool for Adrenal Insufficiency
Yoon Ji Kim, Jung Hee Kim, A Ram Hong, et al.
Endocrinol Metab. 2020;35(3):628-635.

Background: Salivary cortisol is routinely used as a diagnostic test for Cushing syndrome. The diagnostic use of salivary cortisol for adrenal insufficiency (AI), however, is less established. We aimed to...

Original Article

Clinical Study

September 22, 2020


Predicting the Development of Myocardial Infarction in Middle-Aged Adults with Type 2 Diabetes: A Risk Model Generated from a Nationwide Population-Based Cohort Study in Korea
Seung-Hwan Lee, Kyungdo Han, Hun-Sung Kim, et al.
Endocrinol Metab. 2020;35(3):636-646.

Background: Most of the widely used prediction models for cardiovascular disease are known to overestimate the risk of this disease in Asians. We aimed to generate a risk model for...

Original Article

Endocrine Research

September 22, 2020


Irisin Regulates the Functions of Hepatic Stellate Cells
Hanh Nguyen Dong, So Young Park, Cong Thuc Le, et al.
Endocrinol Metab. 2020;35(3):647-655.

Background: Hepatic stellate cells (HSCs) are known to play a fundamental role in the progression of liver fibrosis. Once HSCs are activated, they are involved in proliferation, migration, and contractility...

Original Article

Endocrine Research

August 20, 2020


Liver X Receptor β Related to Tumor Progression and Ribosome Gene Expression in Papillary Thyroid Cancer
Seonhyang Jeong, In-Kyu Kim, Hyunji Kim, et al.
Endocrinol Metab. 2020;35(3):656-668.

Background: Intracellular lipid deposition has been reported in thyroid glands in obese animal and human. To understand the regulatory mechanism of lipid metabolism in thyroid cancer, we investigated the expression...
Current Issue
Volume 35(3); Sep 2020
Association of Adipokines with Development and Progression of Nonalcoholic Fatty Liver Disease
Chrysoula Boutari, Nikolaos Perakakis, Christos Socrates Mantzoros
Endocrinol Metab. 2018;33(1):33-43.

Review Article

Mar 21, 2018
Genome-Wide Association Studies of Autoimmune Thyroid Diseases, Thyroid Function, and Thyroid Cancer
Yul Hwangbo, Young Joo Park
Endocrinol Metab. 2018;33(2):175-184.

Review Article

Jun 21, 2018
Effects of Resistance Exercise on Bone Health
A Ram Hong, Sang Wan Kim
Endocrinol Metab. 2018;33(4):435-444.

Review Article

Nov 30, 2018
Evidence of the Possible Harm of Endocrine-Disrupting Chemicals in Humans: Ongoing Debates and Key Issues
Duk-Hee Lee
Endocrinol Metab. 2018;33(1):44-52.

Review Article

Mar 21, 2018
Recent Updates on the Diagnosis and Management of Cushing's Syndrome
Lynnette K. Nieman
Endocrinol Metab. 2018;33(2):139-146.

Review Article

Jun 21, 2018
Long-Term Outcomes Following Thermal Ablation of Benign Thyroid Nodules as an Alternative to Surgery: The Importance of Controlling Regrowth
Jung Suk Sim, Jung Hwan Baek
Endocrinol Metab. 2019;34(2):117-123.

Review Article

Jun 24, 2019
Prognosis of Differentiated Thyroid Carcinoma with Initial Distant Metastasis: A Multicenter Study in Korea
Hosu Kim, Hye In Kim, Sun Wook Kim, et al.
Endocrinol Metab. 2018;33(2):287-295.

Original Article

Jun 21, 2018
Graves' Disease: Can It Be Cured?
Wilmar M. Wiersinga
Endocrinol Metab. 2019;34(1):29-38.

Review Article

Mar 21, 2019
Management of Low-Risk Papillary Thyroid Cancer
Nicole M. Iñiguez-Ariza, Juan P. Brito
Endocrinol Metab. 2018;33(2):185-194.

Review Article

Jun 21, 2018
Latent Autoimmune Diabetes in Adults: Current Status and New Horizons
Paolo Pozzilli, Silvia Pieralice
Endocrinol Metab. 2018;33(2):147-159.

Review Article

Jun 21, 2018
Recent Topics in Fibrodysplasia Ossificans Progressiva
Takenobu Katagiri, Sho Tsukamoto, Yutaka Nakachi, et al.
Endocrinol Metab. 2018;33(3):331-338.

Review Article

Sep 18, 2018
Study Protocol of Multicenter Prospective Cohort Study of Active Surveillance on Papillary Thyroid Microcarcinoma (MAeSTro)
Jae Hoon Moon, Ji-hoon Kim, Eun Kyung Lee, et al.
Endocrinol Metab. 2018;33(2):278-286.

Original Article

Jun 21, 2018
Combined Effects of Baicalein and Docetaxel on Apoptosis in 8505c Anaplastic Thyroid Cancer Cells via Downregulation of the ERK and Akt/mTOR Pathways
Chan Ho Park, Se Eun Han, Il Seong Nam-Goong, et al.
Endocrinol Metab. 2018;33(1):121-132.

Original Article

Mar 21, 2018
Nonalcoholic Fatty Liver Disease and Diabetes: An Epidemiological Perspective
Eun-Jung Rhee
Endocrinol Metab. 2019;34(3):226-233.

Review Article

Sep 26, 2019
Associations between Hashimoto Thyroiditis and Clinical Outcomes of Papillary Thyroid Cancer: A Meta-Analysis of Observational Studies
Shinje Moon, Hye Soo Chung, Jae Myung Yu, et al.
Endocrinol Metab. 2018;33(4):473-484.

Original Article

Nov 30, 2018
Effect of Dapagliflozin on Alanine Aminotransferase Improvement in Type 2 Diabetes Mellitus with Non-alcoholic Fatty Liver Disease
Dug-Hyun Choi, Chan-Hee Jung, Ji-Oh Mok, et al.
Endocrinol Metab. 2018;33(3):387-394.

Original Article

Clinical Study

Sep 18, 2018
Implications of Mitochondrial Unfolded Protein Response and Mitokines: A Perspective on Fatty Liver Diseases
Hyon-Seung Yi
Endocrinol Metab. 2019;34(1):39-46.

Review Article

Mar 21, 2019
Genetic Polymorphism Predisposing to Differentiated Thyroid Cancer: A Review of Major Findings of the Genome-Wide Association Studies
Vladimir A. Saenko, Tatiana I. Rogounovitch
Endocrinol Metab. 2018;33(2):164-174.

Review Article

Jun 21, 2018
Skeletal Fragility in Type 2 Diabetes Mellitus
Jakob Starup-Linde, Katrine Hygum, Bente Lomholt Langdahl
Endocrinol Metab. 2018;33(3):339-351.

Review Article

Sep 18, 2018
Radioactive Iodine-Refractory Differentiated Thyroid Cancer and Redifferentiation Therapy
Jierui Liu, Yanqing Liu, Yansong Lin, et al.
Endocrinol Metab. 2019;34(3):215-225.

Review Article

Sep 26, 2019
Recent Progress on Branched-Chain Amino Acids in Obesity, Diabetes, and Beyond
Md Abu Bakkar Siddik, Andrew C. Shin
Endocrinol Metab. 2019;34(3):234-246.

Review Article

Sep 26, 2019
Triglyceride Glucose Index Is Superior to the Homeostasis Model Assessment of Insulin Resistance for Predicting Nonalcoholic Fatty Liver Disease in Korean Adults
Sang Bae Lee, Min Kyung Kim, Shinae Kang, et al.
Endocrinol Metab. 2019;34(2):179-186.

Original Article

Clinical Study

May 20, 2019
Genomic Characterization of Differentiated Thyroid Carcinoma
Young Shin Song, Young Joo Park
Endocrinol Metab. 2019;34(1):1-10.

Namgok Lecture 2018

Mar 21, 2019
Therapeutic Role of Yoga in Type 2 Diabetes
Arkiath Veettil Raveendran, Anjali Deshpandae, Shashank R. Joshi
Endocrinol Metab. 2018;33(3):307-317.

Review Article

Aug 14, 2018
Deficiency of Sphingosine-1-Phosphate Reduces the Expression of Prohibitin and Causes β-Cell Impairment via Mitochondrial Dysregulation
Seok-Woo Hong, Jinmi Lee, Hyemi Kwon, et al.
Endocrinol Metab. 2018;33(3):403-412.

Original Article

Endocrine Research

Sep 18, 2018
Prevalence and Annual Incidence of Thyroid Disease in Korea from 2006 to 2015: A Nationwide Population-Based Cohort Study
Hyemi Kwon, Jin-hyung Jung, Kyung-Do Han, et al.
Endocrinol Metab. 2018;33(2):260-267.

Original Article

Jun 21, 2018
Comparison of Immunohistochemistry and Direct Sanger Sequencing for Detection of the BRAFV600E Mutation in Thyroid Neoplasm
Hye-Seon Oh, Hyemi Kwon, Suyeon Park, et al.
Endocrinol Metab. 2018;33(1):62-69.

Original Article

Jan 30, 2018
Pathophysiology of Type 2 Diabetes in Koreans
Soo Heon Kwak, Kyong Soo Park
Endocrinol Metab. 2018;33(1):9-16.

Review Article

Mar 21, 2018
Bisphenols and Thyroid Hormone
Min Joo Kim, Young Joo Park
Endocrinol Metab. 2019;34(4):340-348.

Review Article

Dec 23, 2019
Effects of Dipeptidyl Peptidase-4 Inhibitors on Renal Outcomes in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis
Jae Hyun Bae, Sunhee Kim, Eun-Gee Park, et al.
Endocrinol Metab. 2019;34(1):80-92.

Original Article

Mar 21, 2019

Endocrinology
and Metabolism

Print ISSN: 2093-596X
Online ISSN: 2093-5978

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