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Review Article

November 9, 2020


Tumor Cells and Cancer-Associated Fibroblasts: A Synergistic Crosstalk to Promote Thyroid Cancer
Laura Fozzatti, Sheue-yann Cheng
Endocrinol Metab. 2020;35(4):673-680.

Thyroid cancer is the most common endocrine malignancy. Although most thyroid cancer patients are successfully treated and have an excellent prognosis, a percentage of these patients will develop aggressive disease...

Review Article

December 23, 2020


Genetic and Environmental Factors Contributing to Visceral Adiposity in Asian Populations
Rachel Williams, Muthu Periasamy
Endocrinol Metab. 2020;35(4):681-695.

Obesity-associated metabolic illnesses are increasing at an alarming rate in Asian countries. A common feature observed in the Asian population is a higher incidence of abdominal obesity—the “skinny-fat” Asian syndrome....

Review Article

December 2, 2020


Updates in the Pathologic Classification of Thyroid Neoplasms: A Review of the World Health Organization Classification
Yanhua Bai, Kennichi Kakudo, Chan Kwon Jung
Endocrinol Metab. 2020;35(4):696-715.

Advances in medical sciences and evidence-based medicine have led to momentous changes in classification and management of thyroid neoplasms. Much progress has been made toward avoiding overdiagnosis and overtreatment of...

Review Article

December 23, 2020


Sarcopenia and Muscle Aging: A Brief Overview
Tam Dao, Alexander E. Green, Yun A Kim, et al.
Endocrinol Metab. 2020;35(4):716-732.

The world is facing the new challenges of an aging population, and understanding the process of aging has therefore become one of the most important global concerns. Sarcopenia is a...

Review Article

December 23, 2020


In Vivo and In Vitro Quantification of Glucose Kinetics: From Bedside to Bench
Il-Young Kim, Sanghee Park, Yeongmin Kim, et al.
Endocrinol Metab. 2020;35(4):733-749.

Like other substrates, plasma glucose is in a dynamic state of constant turnover (i.e., rates of glucose appearance [Ra glucose] into and disappearance [Rd glucose] from the plasma) while staying...

Review Article

December 2, 2020


Percutaneous Adrenal Radiofrequency Ablation: A Short Review for Endocrinologists
Byung Kwan Park
Endocrinol Metab. 2020;35(4):750-755.

Image-guided radiofrequency ablation (RFA) has been accepted as a minimally invasive treatment for adrenal tumors in patients who are unable to undergo adrenalectomy. Accordingly, this treatment has become more readily...

Review Article

December 23, 2020


Coordination of Multiple Cellular Processes by NR5A1/Nr5a1
Ken-ichirou Morohashi, Miki Inoue, Takashi Baba
Endocrinol Metab. 2020;35(4):756-764.

The agenesis of the gonads and adrenal gland in revealed by knockout mouse studies strongly suggested a crucial role for Nr5a1 (SF-1 or Ad4BP) in organ development. In relation to...

Review Article

December 23, 2020


Embryonic Development and Adult Regeneration of the Adrenal Gland
Ji-Hoon Kim, Man Ho Choi
Endocrinol Metab. 2020;35(4):765-773.

The adrenal gland plays a pivotal role in an organism’s health span by controlling the endocrine system. Decades of research on the adrenal gland have provided multiscale insights into the...

Review Article

December 23, 2020


Minimally Invasive Adrenal Surgery
JungHak Kwak, Kyu Eun Lee
Endocrinol Metab. 2020;35(4):774-783.

Since the introduction of minimally invasive surgery, laparoscopic adrenalectomy has become the main treatment option for adrenal masses. Various studies have reported that laparoscopic adrenalectomy showed fewer postoperative complications and...

Original Article

Clinical Study

November 25, 2020


The Association of Overt and Subclinical Hyperthyroidism with the Risk of Cardiovascular Events and Cardiovascular Mortality: Meta-Analysis and Systematic Review of Cohort Studies
Seo Young Sohn, Eunyoung Lee, Min Kyung Lee, et al.
Endocrinol Metab. 2020;35(4):786-800.

Background: Whether hyperthyroidism is an independent risk factor for cardiovascular events remains controversial. We aimed to evaluate the association of overt and subclinical hyperthyroidism with the risk of ischemic heart...

Original Article

Clinical Study

November 24, 2020


Identification of Novel Genetic Variants Related to Trabecular Bone Score in Community-Dwelling Older Adults
Sung Hye Kong, Ji Won Yoon, Jung Hee Kim, et al.
Endocrinol Metab. 2020;35(4):801-810.

Background: As the genetic variants of trabecular bone microarchitecture are not well-understood, we performed a genome-wide association study to identify genetic determinants of bone microarchitecture analyzed by trabecular bone score...

Original Article

Clinical Study

November 20, 2020


Trends in the Diagnosis and Treatment of Patients with Medullary Thyroid Carcinoma in Korea
Hwa Young Ahn, Jae Eun Chae, Hyemi Moon, et al.
Endocrinol Metab. 2020;35(4):811-819.

Background: Thyroid cancer is becoming increasingly common worldwide, but little is known about the epidemiology of medullary thyroid carcinoma (MTC). This study investigated the current status of the incidence and...

Original Article

Clinical Study

November 18, 2020


Insulin Secretion and Insulin Resistance Trajectories over 1 Year after Kidney Transplantation: A Multicenter Prospective Cohort Study
Jun Bae Bang, Chang-Kwon Oh, Yu Seun Kim, et al.
Endocrinol Metab. 2020;35(4):820-829.

Background: We investigated the changing patterns of insulin secretion and resistance and risk factors contributing to the development of post-transplant diabetes mellitus (PTDM) in kidney recipients under tacrolimus-based immunosuppression regimen...

Original Article

Clinical Study

November 18, 2020


Clinical Outcomes after Early and Delayed Radioiodine Remnant Ablation in Patients with Low-Risk Papillary Thyroid Carcinoma: Propensity Score Matching Analysis
Jonghwa Ahn, Meihua Jin, Eyun Song, et al.
Endocrinol Metab. 2020;35(4):830-837.

Background: The clinical outcomes of delayed radioiodine remnant ablation (RRA) therapy in patients with low-risk papillary thyroid carcinoma (PTC) are unclear. We aimed to evaluate the clinical impact of the...

Original Article

Clinical Study

December 2, 2020


Changes in Glucose Metabolism after Adrenalectomy or Treatment with a Mineralocorticoid Receptor Antagonist for Primary Aldosteronism
Yu-Fang Lin, Kang-Yung Peng, Chia-Hui Chang, et al.
Endocrinol Metab. 2020;35(4):838-846.

Background: Data on the effects of excess aldosterone on glucose metabolism are inconsistent. This study compared the changes in glucose metabolism in patients with primary aldosteronism (PA) after adrenalectomy or...

Original Article

Clinical Study

November 18, 2020


Cross-Sectional and Longitudinal Examination of Insulin Sensitivity and Secretion across Puberty among Non-Hispanic Black and White Children
Shannon E. Marwitz, Megan V. Gaines, Sheila M. Brady, et al.
Endocrinol Metab. 2020;35(4):847-857.

Background: Few studies using criterion measures of insulin sensitivity (SI) and insulin secretory capacity (ISC) have been conducted across puberty to adulthood. We examined how SI and ISC change from...

Original Article

Clinical Study

December 23, 2020


Genetic Analysis and Clinical Characteristics of Hereditary Pheochromocytoma and Paraganglioma Syndrome in Korean Population
Heewon Choi, Kyoung Jin Kim, Namki Hong, et al.
Endocrinol Metab. 2020;35(4):858-872.

Background: Pheochromocytoma and paragangliomas (PPGL) are hereditary in approximately 30% to 40% cases. With the advancement of genetic analysis techniques, including next-generation sequencing (NGS), there were attempts to classify PPGL...

Original Article

Clinical Study

December 23, 2020


Predictive Performance of Glycated Hemoglobin for Incident Diabetes Compared with Glucose Tolerance Test According to Central Obesity
Suji Yoo, Jaehoon Jung, Hosu Kim, et al.
Endocrinol Metab. 2020;35(4):873-881.

Background: To examine whether glycated hemoglobin (HbA1c) test would be a suitable screening tool for detecting high-risk subjects for diabetes compared to oral glucose tolerance test (OGTT) according to accompanied...

Original Article

Clinical Study

December 2, 2020


Efficacy and Safety of Pitavastatin in a Real-World Setting: Observational Study Evaluating SaFety in Patient Treated with Pitavastatin in Korea (PROOF Study)
In-Kyung Jeong, Sung-Rae Kim
Endocrinol Metab. 2020;35(4):882-891.

Background: While randomized controlled trials provide useful information about drug safety and efficacy, they do not always reflect the observed results in the real world. The prospective, observational, non-comparative trial...

Original Article

Clinical Study

December 23, 2020


Association between Secondhand Smoke Exposure and Metabolic Syndrome in 118,609 Korean Never Smokers Verified by Self-Reported Questionnaire and Urine Cotinine
Ji Hye Kim, Byung Jin Kim, Young Youl Hyun, et al.
Endocrinol Metab. 2020;35(4):892-900.

Background: No study has reported the association between secondhand smoke (SHS) exposure and metabolic syndrome (MetS) in self-reported never smokers verified by both self-reported questionnaire and urine cotinine. Methods: A total...

Original Article

Clinical Study

December 10, 2020


Clinical Outcomes of COVID-19 Patients with Type 2 Diabetes: A Population-Based Study in Korea
Ji Hong You, Sang Ah Lee, Sung-Youn Chun, et al.
Endocrinol Metab. 2020;35(4):901-908.

Background: The aim of this study was to evaluate clinical outcomes in coronavirus disease 2019 (COVID-19) positive patients with type 2 diabetes compared to those without diabetes in Korea. Methods: We...

Original Article

Clinical Study

December 23, 2020


Whole Exome Sequencing Identifies Novel Genetic Alterations in Patients with Pheochromocytoma/Paraganglioma
Soo Hyun Seo, Jung Hee Kim, Man Jin Kim, et al.
Endocrinol Metab. 2020;35(4):909-917.

Background: Pheochromocytoma and paragangliomas (PPGL) are known as tumors with the highest level of heritability, approximately 30% of all cases. Clinical practice guidelines of PPGL recommend genetic testing for germline...

Original Article

Clinical Study

December 23, 2020


Efficacy of Intraoperative Neuromonitoring in Reoperation for Recurrent Thyroid Cancer Patients
Jang-il Kim, Su-jin Kim, Zhen Xu, et al.
Endocrinol Metab. 2020;35(4):918-924.

Background: The use of intraoperative neuromonitoring (IONM) in thyroid surgery to preserve recurrent laryngeal nerve (RLN) function has been widely accepted. We aimed to evaluate the usefulness of IONM in...

Original Article

Clinical Study

December 10, 2020


Association of Hyperparathyroidism and Papillary Thyroid Cancer: A Multicenter Retrospective Study
Chaiho Jeong, Hye In Kwon, Hansang Baek, et al.
Endocrinol Metab. 2020;35(4):925-932.

Background: Concomitant papillary thyroid cancer (PTC) and hyperparathyroidism (HPT) have been reported in several studies. Our study aimed to investigate the incidence of concomitant PTC in HPT patients upon preoperative...

Original Article

Clinical Study

December 23, 2020


Variabilities in Weight and Waist Circumference and Risk of Myocardial Infarction, Stroke, and Mortality: A Nationwide Cohort Study
Da Hye Kim, Ga Eun Nam, Kyungdo Han, et al.
Endocrinol Metab. 2020;35(4):933-942.

Background: Evidence regarding the association between variabilities in obesity measures and health outcomes is limited. We aimed to examine the association between variabilities in obesity measures and cardiovascular outcomes and...

Original Article

Endocrine Research

December 2, 2020


Clusterin Protects Lipotoxicity-Induced Apoptosis via Upregulation of Autophagy in Insulin-Secreting Cells
Seok-Woo Hong, Jinmi Lee, Min Jeong Kim, et al.
Endocrinol Metab. 2020;35(4):943-953.

Background: There is a great need to discover factors that could protect pancreatic β-cells from apoptosis and thus prevent diabetes mellitus. Clusterin (CLU), a chaperone protein, plays an important role...
Current Issue
Volume 35(4); Dec 2020
Long-Term Outcomes Following Thermal Ablation of Benign Thyroid Nodules as an Alternative to Surgery: The Importance of Controlling Regrowth
Jung Suk Sim, Jung Hwan Baek
Endocrinol Metab. 2019;34(2):117-123.

Review Article

Jun 24, 2019
Graves' Disease: Can It Be Cured?
Wilmar M. Wiersinga
Endocrinol Metab. 2019;34(1):29-38.

Review Article

Mar 21, 2019
Nonalcoholic Fatty Liver Disease and Diabetes: An Epidemiological Perspective
Eun-Jung Rhee
Endocrinol Metab. 2019;34(3):226-233.

Review Article

Sep 26, 2019
Implications of Mitochondrial Unfolded Protein Response and Mitokines: A Perspective on Fatty Liver Diseases
Hyon-Seung Yi
Endocrinol Metab. 2019;34(1):39-46.

Review Article

Mar 21, 2019
Recent Progress on Branched-Chain Amino Acids in Obesity, Diabetes, and Beyond
Md Abu Bakkar Siddik, Andrew C. Shin
Endocrinol Metab. 2019;34(3):234-246.

Review Article

Sep 26, 2019
Triglyceride Glucose Index Is Superior to the Homeostasis Model Assessment of Insulin Resistance for Predicting Nonalcoholic Fatty Liver Disease in Korean Adults
Sang Bae Lee, Min Kyung Kim, Shinae Kang, et al.
Endocrinol Metab. 2019;34(2):179-186.

Original Article

Clinical Study

May 20, 2019
Genomic Characterization of Differentiated Thyroid Carcinoma
Young Shin Song, Young Joo Park
Endocrinol Metab. 2019;34(1):1-10.

Namgok Lecture 2018

Mar 21, 2019
Effects of Dipeptidyl Peptidase-4 Inhibitors on Renal Outcomes in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis
Jae Hyun Bae, Sunhee Kim, Eun-Gee Park, et al.
Endocrinol Metab. 2019;34(1):80-92.

Original Article

Mar 21, 2019
Bisphenols and Thyroid Hormone
Min Joo Kim, Young Joo Park
Endocrinol Metab. 2019;34(4):340-348.

Review Article

Dec 23, 2019
Impact of Skeletal Muscle Mass on Metabolic Health
Gyuri Kim, Jae Hyeon Kim
Endocrinol Metab. 2020;35(1):1-6.

Namgok Lecture 2019

Mar 19, 2020
Radioactive Iodine-Refractory Differentiated Thyroid Cancer and Redifferentiation Therapy
Jierui Liu, Yanqing Liu, Yansong Lin, et al.
Endocrinol Metab. 2019;34(3):215-225.

Review Article

Sep 26, 2019
Medical Big Data Is Not Yet Available: Why We Need Realism Rather than Exaggeration
Hun-Sung Kim, Dai-Jin Kim, Kun-Ho Yoon
Endocrinol Metab. 2019;34(4):349-354.

Review Article

Dec 23, 2019
Natural Killer Cells and Thyroid Diseases
Eun Kyung Lee, John B. Sunwoo
Endocrinol Metab. 2019;34(2):132-137.

Review Article

Jun 24, 2019
Association between Circulating Irisin and C-Reactive Protein Levels: A Systematic Review and Meta-Analysis
Elham Eslampour, Farzad Ebrahimzadeh, Amir Abbasnezhad, et al.
Endocrinol Metab. 2019;34(2):140-149.

Original Article

Clinical Study

Jun 24, 2019
Postoperative Thyroid-Stimulating Hormone Levels Did Not Affect Recurrence after Thyroid Lobectomy in Patients with Papillary Thyroid Cancer
Myung-Chul Lee, Min Joo Kim, Hoon Sung Choi, et al.
Endocrinol Metab. 2019;34(2):150-157.

Original Article

Clinical Study

May 10, 2019
Encountering COVID-19 as Endocrinologists
Eun-Jung Rhee, Jung Hee Kim, Sun Joon Moon, et al.
Endocrinol Metab. 2020;35(2):197-205.

Review Article

Jun 23, 2020
Long-Term Results of Thermal Ablation of Benign Thyroid Nodules: A Systematic Review and Meta-Analysis
Se Jin Cho, Jung Hwan Baek, Sae Rom Chung, et al.
Endocrinol Metab. 2020;35(2):339-350.

Original Article

Clinical Study

Jun 24, 2020
The Role of Glucagon-Like Peptide 1 Receptor Agonists and Sodium-Glucose Cotransporter 2 Inhibitors in Reducing Cardiovascular Events in Patients with Type 2 Diabetes
Gwang Sil Kim, Joong Hyun Park, Jong Chul Won
Endocrinol Metab. 2019;34(2):106-116.

Review Article

May 9, 2019
Prevalence and Current Management of Cardiovascular Risk Factors in Korean Adults Based on Fact Sheets
Eun-Jung Rhee
Endocrinol Metab. 2020;35(1):85-94.

Review Article

Mar 19, 2020
Impact of the Dynamic Change of Metabolic Health Status on the Incident Type 2 Diabetes: A Nationwide Population-Based Cohort Study
Jung A Kim, Da Hye Kim, Seon Mee Kim, et al.
Endocrinol Metab. 2019;34(4):406-414.

Original Article

Clinical Study

Dec 23, 2019
A Review of the Effects of Glucagon-Like Peptide-1 Receptor Agonists and Sodium-Glucose Cotransporter 2 Inhibitors on Lean Body Mass in Humans
Jack Alistair Sargeant, Joseph Henson, James Adam King, et al.
Endocrinol Metab. 2019;34(3):247-262.

Review Article

Sep 26, 2019
Changes in Thyroid Peroxidase and Thyroglobulin Antibodies Might Be Associated with Graves' Disease Relapse after Antithyroid Drug Therapy
Yun Mi Choi, Mi Kyung Kwak, Sang Mo Hong, et al.
Endocrinol Metab. 2019;34(3):268-274.

Original Article

Clinical Study

Sep 26, 2019
Serotonin Regulates De Novo Lipogenesis in Adipose Tissues through Serotonin Receptor 2A
Ko Eun Shong, Chang-Myung Oh, Jun Namkung, et al.
Endocrinol Metab. 2020;35(2):470-479.Correction in: Endocrinol Metab 2020;35(3):672

Original Article

Endocrine Research

Jun 24, 2020
Unmet Clinical Needs in the Treatment of Patients with Thyroid Cancer
Won Bae Kim, Min Ji Jeon, Won Gu Kim, et al.
Endocrinol Metab. 2020;35(1):14-25.

Review Article

Mar 19, 2020
Visceral-to-Subcutaneous Abdominal Fat Ratio Is Associated with Nonalcoholic Fatty Liver Disease and Liver Fibrosis
Chan-Hee Jung, Eun-Jung Rhee, Hyemi Kwon, et al.
Endocrinol Metab. 2020;35(1):165-176.

Original Article

Clinical Study

Mar 19, 2020
Trends in Hyperglycemic Crisis Hospitalizations and in- and out-of-Hospital Mortality in the Last Decade Based on Korean National Health Insurance Claims Data
Ji Hong You, Sun Ok Song, Se Hee Park, et al.
Endocrinol Metab. 2019;34(3):275-281.

Original Article

Clinical Study

Sep 26, 2019
Current Management of Type 2 Diabetes Mellitus in Primary Care Clinics in Korea
Da Hea Seo, Shinae Kang, Yong-ho Lee, et al.
Endocrinol Metab. 2019;34(3):282-290.

Original Article

Clinical Study

Sep 26, 2019
Does Radiofrequency Ablation Induce Neoplastic Changes in Benign Thyroid Nodules: A Preliminary Study
Su Min Ha, Jun Young Shin, Jung Hwan Baek, et al.
Endocrinol Metab. 2019;34(2):169-178.

Original Article

Clinical Study

May 15, 2019
Comparison of Natural Course between Thyroid Cancer Nodules and Thyroid Benign Nodules
Kyun-Jin Yun, Jeonghoon Ha, Min-Hee Kim, et al.
Endocrinol Metab. 2019;34(2):195-202.

Original Article

Clinical Study

Jun 24, 2019
Human Immunodeficiency Virus Infection and the Endocrine System
Dana Zaid, Yona Greenman
Endocrinol Metab. 2019;34(2):95-105.

Review Article

May 20, 2019

Endocrinology
and Metabolism

Print ISSN: 2093-596X
Online ISSN: 2093-5978

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