A Case of Graves' Disease with Pheochromocytoma.

Kim, Hye Sook; Joo, Hyung Joon; Choi, Yoon Seok; Kim, Eun Sun; Park, Soo Yeon; Lee, Yun Jeong; Kim, Hee Young; Seo, Ji A; Kim, Sin Gon; Choi, Dong Seop

doi:2007.22.6.465

Endocrinol Metab > Volume 22(6); 2007 > Article

Case Report

Journal of Korean Endocrine Society 2007;22(6):465-469.
DOI: https://doi.org/10.3803/jkes.2007.22.6.465 Published online December 1, 2007.

A Case of Graves' Disease with Pheochromocytoma.

Hye Sook Kim, Hyung Joon Joo, Yoon Seok Choi, Eun Sun Kim, Soo Yeon Park, Yun Jeong Lee, Hee Young Kim, Ji A Seo, Sin Gon Kim, Dong Seop Choi

Department of Internal Medicine, Korea University College of Medicine, Korea.

Abstract

Graves' disease is an autoimmune disorder in which thyrotropin-stimulating hormone receptor antibodies stimulate the thyroid gland. Stress hormones such as catecholamine are known to play important roles in the pathogenesis of Graves' disease. Pheochromocytoma with Graves' disease is extremely rare, and no case has been reported within the Republic of Korea. However, according to previous studies conducted abroad, pheochromocytoma influences the pathogenesis of Graves' disease by producing excessive cathecholamine. In the present report, we describe a 65-year-old female patient with paroxysmal hypertension and rapidly progressive body weight loss who was diagnosed as having Graves'disease with pheochromocytoma.

Key Words: catecholamine, graves' disease, pheochromocytoma