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HOME > Endocrinol Metab > Volume 25(3); 2010 > Article
Case Report Intrathyroidal Metastasis of Lung Adenocarcinoma Presenting as Subacute Thyroiditis.
Hyun Sung Shin, Young Kwang Choo, Won Ae Lee, Hyun Kyung Chung
Endocrinology and Metabolism 2010;25(3):226-230
DOI: https://doi.org/10.3803/EnM.2010.25.3.226
Published online: September 1, 2010
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1Department of Endocrinology and Metabolism, College of Medicine, Dankook University, Cheonan, Korea. chkendo@dankook.ac.kr
2Department of Pathology, College of Medicine, Dankook University, Cheonan, Korea.

One of the rare diseases for differential diagnosis of subacute thyroiditis is metastases within the thyroid gland. We report here on a 72-year-old-woman with painful goiter and signs of hyperthyroidism. Her serum concentration of thyroid hormone was in the upper limit of normal, and the uptake of radioactive iodine by the thyroid was completely depressed. Although subacute thyroiditis was suspected, an additional work up that included a chest CT scan was done for the combined cough and chronic weakness. The result was lung cancer with metastatic involvement of the thyroid and multiple lymph nodes. She refused further anti-cancer therapy and died 5 months after the diagnosis. For the differential diagnosis of such a rare case, careful examination is important even in patients with the typical symptoms and laboratory findings of subacute thyroiditis.

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