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Division of Endocrinology and Metabolism, Department of Internal Medicine, Yeouido St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
Copyright © 2020 Korean Endocrine Society
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
CONFLICTS OF INTEREST
No potential conflict of interest relevant to this article was reported.
AUTHOR CONTRIBUTIONS
Conception or design: K.H.S., M.K.K. Acquisition, analysis, or interpretation of data: H.N.J., H.S.K., K.H.B., K.H.S., M.K.K. Drafting the work or revising: H.N.J., M.K.K. Final approval of the manuscript: H.N.J., M.K.K.
Characteristic | Value |
---|---|
Number | 36 |
Age, yr | 56.9±9.4 |
Male sex | 16 (44) |
Duration of diabetes, yr | 15.1±8.1 |
Body mass index, kg/m2 | 25.7±3.9 |
Serum creatinine, mg/dL | 0.73±0.2 |
Hemoglobin, g/dL | 14.2±1.7 |
Albumin, g/dL | 4.4±0.3 |
FBG, mg/dL | 170.8±36.8 |
HbA1c, % | 8.0±0.9 |
Glycated albumin, % | 20.9±4.1 |
Use of metformin | 36 (100) |
Use of insulin | 6 (17) |
Use of sulfonylurea | 24 (67) |
Use of dipeptidyl peptidase-4 inhibitors | 28 (78) |
Variable | Baseline | 1 month | P value |
---|---|---|---|
HbA1c, % | 8.0±0.9 | 7.8±0.9 | 0.014 |
Glycated albumin, % | 20.9±4.1 | 20.2±4.0 | 0.019 |
FBG, mg/dL | 170.8±36.8 | 158.1±37.7 | 0.097 |
MBG from CGM, mg/dL | 179.3±35.7 | 174.2±35.6 | 0.286 |
Prebreakfast glucose from CGM, mg/dL | 158.8±40.6 | 155.2±41.7 | 0.425 |
Glycation gap | 0.27±0.58 | 0.22±0.57 | 0.273 |
FBG-based HGI | −0.25±0.79 | −0.24±0.78 | 0.970 |
MBG-based HGI | 0.09±0.60 | 0.02±0.60 | 0.345 |
Prebreakfast glucose-based HGI | −0.09±0.78 | −0.18±0.75 | 0.425 |
Variable | MBG-based HGI | Prebreakfast glucose-based HGI | ||
---|---|---|---|---|
|
| |||
r | P value | r | P value | |
Prebreakfast glucose-based HGI | 0.867 | <0.001 | - | - |
| ||||
FBG-based HGI | 0.687 | <0.001 | 0.823 | <0.001 |
| ||||
Glycation gap | 0.810 | <0.001 | 0.692 | <0.001 |
Values are expressed as mean±standard deviation or number (%). FBG, fasting blood glucose; HbA1c, glycated hemoglobin.
Values are expressed as mean±standard deviation. HGI, hemoglobin glycation index; HbA1c, glycated hemoglobin; FBG, fasting blood glucose; MBG, mean blood glucose; CGM, continuous glucose monitoring.
HGI, hemoglobin glycation index; MBG, mean blood glucose; FBG, fasting blood glucose.