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1Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
2Department of Medical Informatics, College of Medicine, The Catholic University of Korea, Seoul, Korea
3Department of Statistics and Actuarial Science, Soongsil University, Seoul, Korea
4Department of Medical Statistics, College of Medicine, The Catholic University of Korea, Seoul, Korea
5College of Medicine, The Catholic University of Korea, Seoul, Korea
6Division of Endocrinology and Metabolism, Department of Internal Medicine, Yeouido St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
Copyright © 2023 Korean Endocrine Society
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
CONFLICTS OF INTEREST
No potential conflict of interest relevant to this article was reported.
AUTHOR CONTRIBUTIONS
Conception or design: S.H.L., K.H., M.K.K. Acquisition, analysis, or interpretation of data: S.H.L., J.Y., K.H., S.W.L., M.K.K. Drafting the work or revising: S.H.L., J.Y., M.K.K. Final approval of the manuscript: S.H.L., J.Y., K.H., S.W.L., S.Y.Y., H.S.K., J.H.C., K.H.Y., M.K.K.
Variable | No. of events (%) | Univariate | Multivariatea | |
---|---|---|---|---|
Age, yr | ||||
<25 | 29 (0.2) | 1 (reference) | 1 (reference) | |
25–29 | 447 (0.39) | 1.92 (1.32–2.80) | 2.02 (1.39–2.95) | |
30–34 | 946 (0.74) | 3.71 (2.57–5.38) | 3.36 (2.32–4.87) | |
≥35 | 602 (1.76) | 8.87 (6.11–12.88) | 6.18 (4.25–9.00) | |
Body mass index, kg/m2 | ||||
<18.5 | 124 (0.27) | 0.55 (0.46–0.66) | 0.64 (0.53–0.77) | |
18.5–22.9 | 952 (0.5) | 1 (reference) | 1 (reference) | |
23–24.9 | 355 (1.17) | 2.36 (2.08–2.66) | 1.76 (1.56–2.00) | |
25–29.9 | 443 (2.06) | 4.20 (3.75–4.71) | 2.36 (2.09–2.67) | |
≥30 | 150 (3.99) | 8.30 (6.97–9.89) | 3.30 (2.73–3.98) | |
Smoking status | ||||
No | 1,879 (0.67) | 1 (reference) | 1 (reference) | |
Current | 145 (1.39) | 2.10 (1.77–2.48) | 1.62 (1.36,1.93) | |
Fasting blood glucose, mg/dL | ||||
<90 | 637 (0.36) | 1 (reference) | 1 (reference) | |
90–99 | 697 (0.78) | 2.16 (1.94–2.40) | 1.82 (1.63–2.03) | |
100–109 | 409 (1.93) | 5.41 (4.77–6.13) | 3.72 (3.27–4.23) | |
110–125 | 281 (5.42) | 15.77 (13.67–18.20) | 9.15 (7.88–10.64) | |
Total cholesterol, mg/dL | ||||
<160 | 415 (0.5) | 1 (reference) | 1 (reference) | |
160–199 | 925 (0.62) | 1.25 (1.11–1.40) | 1.02 (0.91–1.15) | |
200–239 | 527 (1.05) | 2.13 (1.87–2.42) | 1.26 (1.10–1.44) | |
≥240 | 157 (1.96) | 4.01 (3.33–4.83) | 1.62 (1.34–1.97) | |
γ-GTP, IU/L | ||||
<10 | 121 (0.35) | 1 (reference) | 1 (reference) | |
10–19 | 1,110 (0.55) | 1.56 (1.29–1.88) | 1.37 (1.13–1.65) | |
≥20 | 793 (1.47) | 4.24 (3.50–5.14) | 2.17 (1.78–2.65) |