Endocrinol Metab > Volume 22(3); 2007 > Article
Journal of Korean Endocrine Society 2007;22(3):235-240.
DOI: https://doi.org/10.3803/jkes.2007.22.3.235    Published online June 1, 2007.
A Patient with Concurrent Medullary and Papillary Carcinoma of the Thyroid.
Seung Hee Yoo, Keun Joon Lim, Seung Hwan Lee, Ji Hyun Kim, Soon Hwa Hong, Jae Hyoung Cho, Chan Kwon Jung, Hyuk Sang Kwon, Kun Ho Yoon, Min Sik Kim, Bong Yun Cha, Ho Young Son
1Department of Internal Medicine, The Catholic University of Korea, College of Medicine, Korea.
2Department of Pathology, The Catholic University of Korea, College of Medicine, Korea.
3Department of Otolaryngology, The Catholic University of Korea, College of Medicine, Korea.
The origin of medullary thyroid carcinoma and papillary thyroid carcinoma are embryogenically different, so these tumors have been thought to be independent of each other. We experienced a case of concurrent medullary and papillary thyroid carcinoma in one patient. The patient underwent total thyroidectomy and both two tumors were located at different lobes, respectively. Both tumors showed their own characteristic pathologic and immunohistochemical findings. The patient's elevated calcitonin level returned to the normal range after operation and there has been no evidence of recurrence. It is still controversial whether the concurrency is just coincidental or it arises from activation of a common tumorigenic pathway.
Key Words: Concurrent tumor, Medullary carcinoma, Papillary carcinoma

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