Langerhans Cell Histiocytosis in the Thyroid and Draining Lymph Nodes: A Case Report.

Chung, Dong Hae; Ha, Seung Yeon; Cho, Hyun Yee; Kim, Na Rae; An, Jung Suk; Lee, Young Don; Park, Sanghui

doi:2012.27.2.138

Endocrinol Metab > Volume 27(2); 2012 > Article

Case Report

Endocrinology and Metabolism 2012;27(2):138-141.
DOI: https://doi.org/10.3803/EnM.2012.27.2.138 Published online June 20, 2012.

Langerhans Cell Histiocytosis in the Thyroid and Draining Lymph Nodes: A Case Report.

Dong Hae Chung, Seung Yeon Ha, Hyun Yee Cho, Na Rae Kim, Jung Suk An, Young Don Lee, Sanghui Park

¹Department of Pathology, Gachon University School of Medicine, Incheon, Korea.
²Department of Surgery, Gachon University School of Medicine, Incheon, Korea.
³Department of Pathology, Ewha Womans University School of Medicine, Seoul, Korea. spark0430@ewha.ac.kr

Abstract

A 53-year-old woman was presented with several 0.3-0.6 cm-sized nodules within the right lobe of the thyroid. Histologic sections of the thyroid demonstrated multiple papillary microcarcinomas in the background of lymphocytic thyroiditis, with a small focus of Langerhans cell histiocytosis (LCH). Small LCH nodules were also found in the draining cervical lymph nodes. Although the association of LCH with papillary thyroid carcinoma in the thyroid has been reported, their co-existence with LCH in the draining lymph nodes is very rare.

Key Words: Langerhans cell histiocytosis, Thyroid papillary carcinoma, Thyroid gland