Journal of Korean Endocrine Society 2002;17(2):286-291.
Published online April 1, 2002.
A Case of Adrenocortical Adenoma Causing Cushing's Syndrome with Contralateral Nonfunctioning Adenoma.
Sun Young Kyung, Hye Sook Hahn, Hyo Joong Yoon, Young Ha Hwang, Chan Jong Seo, Yeon Sil Jeong, Hong Kyu Kim, Hye Young Park, Hyung Sik Kim, Jeong Nam Lee, Seung Yeon Ha, Moon Ho Kang
1Division of Endocrinology and Metabolism, Department of Internal Medicine, Gachon Medical School, Gil Medical Center, Incheon, Korea.
2Department of Radiology, Gachon Medical School, Gil Medical Center, Incheon, Korea.
3Department of General Surgery, Gachon Medical School, Gil Medical Center, Incheon, Korea.
4Department of Anatomical Pathology, Gachon Medical School, Gil Medical Center, Incheon, Korea.
Abstract
We report the case of a 43-year-old woman with Cushing's syndrome showing bilateral adrenococortical adenomas. We performed bilateral selective adrenal vein samplings. Hypersecretion of cortisol on the left sided adrenal tumor was observed, but no evidence of cortisol hypersecretion from the adrenal tumor on the right side was observed. The left adrenal tumor was resected selectively, but the right adrenal gland was reserved. The left adrenal tumor was histologically diagnosed as a adrenal adenoma without any evidence of nodular hyperplasia. Following the resection of the left adrenal gland, no cortisol hypersecretion from the remaining adrenal tumor on the right side was observed until now, suggesting that a selective adrenalectomy of functioning adenoma may be an acceptable treatment modality.
Key Words: Cushing's syndrome, Bilateral adrenal adenoma, Selective adrenalectomy


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