Endocrinology and Metabolism

Review Article

Obesity and Metabolism
Dopaminergic Control of the Feeding Circuit: Ja-Hyun Baik; Endocrinol Metab. 2021;36(2):229-239. Published online April 6, 2021; DOI: https://doi.org/10.3803/EnM.2021.979

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There is increasing evidence demonstrating that reward-related motivational food intake is closely connected with the brain’s homeostatic system of energy balance and that this interaction might be important in the integrative control of feeding behavior. Dopamine regulates motivational behavior, including feeding behaviors, and the dopamine reward system is recognized as the most prominent system that controls appetite and motivational and emotional drives for food. It appears that the dopamine system exerts a critical role in the control of feeding behavior not only by the reward-related circuit, but also by contributing to the homeostatic circuit of food intake, suggesting that dopamine plays an integrative role across the converging circuitry of control of food intake by linking energy state-associated signals to reward-related behaviors. This review will cover and discuss up-to-date findings on the dopaminergic control of food intake by both the reward-related circuit and the homeostatic hypothalamic system.

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Original Article

Intermuscular Adipose Tissue Content and Intramyocellular Lipid Fatty Acid Saturation Are Associated with Glucose Homeostasis in Middle-Aged and Older Adults: Jung Eun Kim, Keagan Dunville, Junjie Li, Ji Xin Cheng, Travis B. Conley, Cortni S. Couture, Wayne W. Campbell; Endocrinol Metab. 2017;32(2):257-264. Published online May 29, 2017; DOI: https://doi.org/10.3803/EnM.2017.32.2.257

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Abstract PDF Supplementary Material PubReader

Background

Insulin resistance is associated with the higher content of intermuscular adipose tissue (IMAT) and the saturation of intramyocellular lipid (IMCL), but a paucity of data exist in humans. This study examined associations among IMAT content, IMCL saturation, and fasting glucose concentration in middle-aged and older adults with overweight or obesity.

Methods

Seventy-five subjects (26 males, 49 females) were recruited and thigh muscle and IMAT were assessed using magnetic resonance imaging. Vastus lateralis tissue was acquired from a subset of nine subjects and IMCL content and saturation were assessed using nonlinear dual complex microscopy.

Results

The characteristics of the 75 subjects were as follows: age 59±11 years, body mass index 30±5 kg/m², fasting glucose concentration 5.2±0.5 mmol/L, fasting insulin concentration 12.2±7.3 µU/mL, fasting homeostatic model assessment of insulin resistance (HOMA-IR) 2.9±2.0 (mean±SD). IMAT to muscle tissue (MT) volume ratio was positively associated with the saturated fatty acid to unsaturated fatty acid ratio in IMCL. IMAT:MT was positively associated with fasting glucose concentration and HOMA-IR. IMCL saturation was positively associated with fasting glucose concentration while muscle cell area, IMCL area, and % IMCL in muscle cell were not associated with fasting glucose concentration.

Conclusion

These results indicate that higher intermuscular fat content and IMCL saturation may impact fasting glucose concentration in middle-aged and older adults with overweight or obesity. The centralization of adipose tissue in the appendicular region of the body may promote insulin resistance.

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Journal of Clinical Densitometry.2020; 23(4): 611. CrossRef
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Journal of Cellular Physiology.2019; 234(12): 21630. CrossRef
Differential Relationship between Intermuscular Adipose Depots with Indices of Cardiometabolic Health
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International Journal of Endocrinology.2018; 2018: 1. CrossRef
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Nutrition.2018; 46: 97. CrossRef

Review Article

Bone Metabolism
Recent Progress in Osteocyte Research: Paola Divieti Pajevic; Endocrinol Metab. 2013;28(4):255-261. Published online December 12, 2013; DOI: https://doi.org/10.3803/EnM.2013.28.4.255

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Abstract PDF PubReader

The last decade has seen an exponential increase in our understanding of osteocytes function and biology. These cells, once considered inert by-standers trapped into the mineralized bone, has now risen to be key regulators of skeletal metabolism, mineral homeostasis, and hematopoiesis. As tools and techniques to study osteocytes improved and expanded, it has become evident that there is more to these cells than initially thought. Osteocytes are now recognized not only as the key responders to mechanical forces but also as orchestrators of bone remodeling and mineral homeostasis. These cells are the primary source of several important proteins, such as sclerostin and fibroblast growth factor 23, that are currently target as novel therapies for bone loss (as the case for antisclerostin antibodies) or phosphate disorders. Better understanding of the intricate cellular and molecular mechanisms that govern osteocyte biology will open new avenue of research and ultimately indentify novel therapeutics to treat bone and mineral disorders. This review summarizes novel findings and discusses future avenues of research.

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Riikka E. Mäkitie, Alice Costantini, Anders Kämpe, Jessica J. Alm, Outi Mäkitie
Frontiers in Endocrinology.2019;[Epub] CrossRef
Calcium fluxes at the bone/plasma interface: Acute effects of parathyroid hormone (PTH) and targeted deletion of PTH/PTH-related peptide (PTHrP) receptor in the osteocytes
Christopher Dedic, Tin Shing Hung, Alan M. Shipley, Akira Maeda, Thomas Gardella, Andrew L. Miller, Paola Divieti Pajevic, Joseph G. Kunkel, Alessandro Rubinacci
Bone.2018; 116: 135. CrossRef
Ex vivo replication of phenotypic functions of osteocytes through biomimetic 3D bone tissue construction
Qiaoling Sun, Saba Choudhary, Ciaran Mannion, Yair Kissin, Jenny Zilberberg, Woo Y. Lee
Bone.2018; 106: 148. CrossRef
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Natalia Campos‐Obando, W Nadia H Koek, Elizabeth R Hooker, Bram CJ van der Eerden, Huibert A Pols, Albert Hofman, Johannes PTM van Leeuwen, Andre G Uitterlinden, Carrie M Nielson, M. Carola Zillikens
Journal of Bone and Mineral Research.2017; 32(6): 1182. CrossRef
Intermittent PTH treatment can delay the transformation of mature osteoblasts into lining cells on the periosteal surfaces
Mi-Gyeong Jang, Ji Yeon Lee, Jae-Yeon Yang, Hyojung Park, Jung Hee Kim, Jung-Eun Kim, Chan Soo Shin, Seong Yeon Kim, Sang Wan Kim
Journal of Bone and Mineral Metabolism.2016; 34(5): 532. CrossRef
The osteoclasts attach to the bone surface where the extracellular calcium concentration decreases
Bilu Xiang, Yang Liu, Lu Xie, Qian Zhao, Ling Zhang, Xueqi Gan, Haiyang Yu
Cell Biochemistry and Biophysics.2016; 74(4): 553. CrossRef
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Christopher P Recknor, Robert R Recker, Charles T Benson, Deborah A Robins, Alan Y Chiang, Jahangir Alam, Leijun Hu, Toshio Matsumoto, Hideaki Sowa, John H Sloan, Robert J Konrad, Bruce H Mitlak, Adrien A Sipos
Journal of Bone and Mineral Research.2015; 30(9): 1717. CrossRef
Promoting effect of 1,25(OH) 2 vitamin D 3 in osteogenic differentiation from induced pluripotent stem cells to osteocyte-like cells
Hiroshi Kato, Hiromi Ochiai-Shino, Shoko Onodera, Akiko Saito, Takahiko Shibahara, Toshifumi Azuma
Open Biology.2015; 5(2): 140201. CrossRef
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Natacha Rosa, Ricardo Simoes, Fernão D. Magalhães, Antonio Torres Marques
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Endocrinology and Metabolism.2014; 29(3): 251. CrossRef

Case Report

Neonatal Tetany Caused by Hyperparathyroidism Undetected During Pregnancy.: Wan Sub Shim, Hee Baek Park, Bong Soo Cha, Sung Kil Lim, Hyun Chul Lee, Kap Bum Huh; J Korean Endocr Soc. 2002;17(2):257-262. Published online April 1, 2002

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Abstract PDF: Primary hyperparathyroidism is rarely encountered during pregnancy but its prompt diagnosis and treatment if encountered during pregnancy is important because it can carry considerable morbidity not only for the mother but also for the fetus. It tends to remain undiagnosed because 50~80% of the patients are asymptomatic. Even if they do demonstrate symptoms, those are often nonspecific. The other reason for non-diagnosis is masking of hypercalcemia due to the change of calcium homeostasis during pregnancy. Neonatal tetany can be a clue for the presence and diagnosis maternal hyperparathyroidism. The asymptomatic patient who is diagnosed postpartum when her newborn is symptomatic should undergo elective parathyroidectomy to avoid future complication. We experienced a woman with undiagnosed primary hyperparathyroidism during pregnancy whose two children suffered neonatal tetany. We report this case along with a review of literature on primary hyperparathyroidism in pregnancy and calcium homeostasis during pregnancy.

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