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1Department of Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea
2Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
Copyright © 2020 Korean Endocrine Society
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
CONFLICTS OF INTEREST
No potential conflict of interest relevant to this article was reported.
Study | Tumor size, cm (LTA:PRA) | Operation time, min (LTA:PRA) | Blood loss, mL (LTA:PRA) | Conversion rate (LTA:PRA) | Time to first oral intake, day (LTA:PRA) | Hospital stay, day (LTA:PRA) | Postoperative pain on POD 1 (LTA:PRA) |
---|---|---|---|---|---|---|---|
Non-RCT | |||||||
Ottlakan et al. (2020) [24] | 5.6:3.5 (P=0.018) | 78.5±12.3:134.5±12.4 (P=0.019) | 65.7±8.4:50.2±10.7 (P=0.147) | 6 (4.4%):5 (18%) (P=0.257) | 1:1 | 4.3±1.6:4.6±2.2 (P=0.237) | NR |
Ban et al. (2020) [21] | 6.2:3.8 (P<0.001) | 145.2±64.6:80.9±26.2 (P<0.001) | 271.8±351.2:35.8±53.6 (P=0.001) | 0:0 | 1.4±0.9:0.3±0.5 (P<.001) | 5.8±2.8:3.3±1.5 (P<0.001) | NR |
Tuncel et al. (2020) [25] | Lt: 4.2:4.0 (P=0.440) Rt: 4.0:4.1 (P=0.731) | 171±73.2:148±55.7 (P=0.04) | 137.9±302.1:50.2±88.9 (P=0.025) | 1 (3.7%):0 | NR | 6.6±3.5:5.3±2.8 (P=0.135) | NR |
Cabalag et al. (2014) [26] | 3.2:3.5 (P=0.999) | 105:90 (P=0.291) | NR | 0:0 | NR | 2:1 (P<0.001) | NR |
Constantinides et al. (2013) [22] | 4.1:2.8 (P=0.033) | 131.7±46.6:86.3±49.5 (P=0.0002) | NR | 0:0 | 11.6±11.0 hr: 4.1±3.3 hr (P=0.001) | 3.5±2.9:1.6±0.8 (P=0.0001) | NR |
Lee et al. (2012) [27] | 3.9:2.6 (P=0.224) | 108.3±34.5:87.2±27.6 (P=0.042) | 74.8±145.2:20.0±41.7 (P=0.139) | 0:0 | 1.2±0.5:0.9±0.3 (P=0.043) | 5.9±3.6:3.0±1.4 (P=0.003) | NR |
Dickson et al. (2011) [28] | 4.0:3.3 (P=0.25) | 144.8±42.4:99.9±23.0 (P=0.0001) | 123.8±204.3:8.4±19.1 (P=0.02) | 1 (4.3%):3 (13%) (P=0.60) | NR | 3.1±1.4:1.9±0.9 (P=0.003) | NR |
|
|||||||
RCT | |||||||
Chai et al. (2019) [19] | 2.9±1.4: 3.0±1.3 | 59.7±18.6:67.6±28.7 (P=0.139) | 16.3±25.4:11.3±22.1 (P=0.368) | 0:1 (2.4%) | 88.1%:87.8% (P=0.573) at POD 0 | 2.2±0.9:2.2±0.4 (P=0.780) | 3.6±1.1:3.3±1.1 (P=0.225) |
Barczynski et al. (2014) [23] | 4.0:3.9 (P=0.815) | 77.3:50.7 (P<0.001) | 97.8:52.8 (P<0.001) | 0:0 | 7.3 hr:4.4 hr (P<0.001) | 4.4:2.9 (P<0.001) | 24.6:7.9 (P<0.001) |
Study | No. of patients/articles (PA:TA) | Extent of surgery (PA:TA) | Laterality (PA:TA) | Tumor size, cm (PA:TA) | EBL, mL (PA:TA) | Recurrence (PA:TA) | Time to recurrence, mo (PA:TA) | Steroid-dependent rate (PA:TA) | Follow-up duration, mo (PA:TA) | Mortality (PA:TA) |
---|---|---|---|---|---|---|---|---|---|---|
Balci et al. (2020) [42] | 40 patients (15:25) | Partial or total adrenalectomy | Unilateral | 42:38.1 (P=0.408) | 30.7:41.6 (P=0.117) | 0:0 | 0 | 0:1/25 (4%) | 15 (12–26) | 0 |
Gomella et al. (2020) [43] | 107 patients | Partial adrenalectomy | Unilateral and bilateral | 2 (1.5–2.8) | NR | 17/107 (15.8%) | 71 (26–127) | 10/107 (9.3%) | 60 (13–131) | NR |
Nagaraja et al. (2015) [7] | 60 articles | Partial adrenalectomy | Unilateral and bilateral | NR | NR | 8% | NR | 15% | NR | NR |
Castinetti et al. (2014) [41] | 82 patients | Partial adrenalectomy | Bilateral | NR | NR | 4/82 (5%) | 9.5±3.1 yr | 35/82 (43%) | 10±9.5 yr | NR |
Fu et al. (2011) [44] | 212 patients (104:108) | Partial or total adrenalectomy | Unilateral | 1.9:1.8 (NS) | 35.3±10:15.1±6 (P=0.01) | 0:0 | 0 | 0:0 | 96 | 0 |
Kaye et al. (2010) [39] | 22 articles | Partial adrenalectomy | Unilateral and bilateral | 2.6 (0.04–9.0) | 72 (0–1,500) | 3% | 113 (36–324) | 5.3% | 56 | NR |
Lee et al. (1996) [40] | 15 patients (14:1) | Partial or total adrenalectomy | Bilateral | 3.3 (0.5–9.0) | 400 (150–1,500) | 3/14 (21%) | 206±106 | 1/14 (7.1%):1/1 (100%) | 138 (7–331) | 2/15 (13.3%) |