A Case of Subclinical Hypothyroidism Associated with Turner's Syndrome.

Han, In Kwon; Lee, Jung Gil; Lee, Sun Wha; Lee, Seong Kyu; Pak, Chan Moon; Chung, Ho Yeon

Case Report

Journal of Korean Endocrine Society 1994;9(1):35-38.
Published online November 6, 2019.

A Case of Subclinical Hypothyroidism Associated with Turner's Syndrome.

In Kwon Han, Jung Gil Lee, Sun Wha Lee, Seong Kyu Lee, Chan Moon Pak, Ho Yeon Chung

Abstract

Recently it is known that Turner's syndrome is frequently associated with hypothyroidism. We report a case of Turner's syndrome associated with subclinical hypothyroidism. A 23-year-old female was admitted to the hospital with complaints of amenorrhea and short stature. She had a mosaicism of 45, X0/46, Xi(X_q) in the cell, cultured from the peripheral blood. The plasma thyroxine and triiodothyronine were normal and there was no clinical symptom of hypothyroidism. But the thyroid-stimulating hormone(TSH) concentration was unusually higher(184 uU/L). She has been treated with the cyclic therapy of conjugated estrogen and medroxyprogesterone, in addition to the thyroxine replacement therapy. After 2 months, the menstruation was restored and TSH was normalized.

Key Words: Turner's syndrome, Subclinical hypothyroidism