A Case of Multiple Osteoporotic Compression Fractures in Young Man with Budd-Chiari Syndrome.

Kim, Sun Hwa; Yang, Tae Un; Choi, Byeong Kwang; Yoo, Hye Jin; Seo, Ji A; Choi, Kyung Mook; Kim, Nan Hee; Kim, Sin Gon; Baik, Sei Hyun; Choi, Dong Seop; Choi, Hae Yoon

doi:2012.27.4.334

Endocrinol Metab > Volume 27(4); 2012 > Article

Case Report

Endocrinology and Metabolism 2012;27(4):334-339.
DOI: https://doi.org/10.3803/EnM.2012.27.4.334 Published online December 20, 2012.

A Case of Multiple Osteoporotic Compression Fractures in Young Man with Budd-Chiari Syndrome.

Sun Hwa Kim, Tae Un Yang, Byeong Kwang Choi, Hye Jin Yoo, Ji A Seo, Kyung Mook Choi, Nan Hee Kim, Sin Gon Kim, Sei Hyun Baik, Dong Seop Choi, Hae Yoon Choi

Division of Endocrinology and Metabolism, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. kahlua99@hanmail.net

Abstract

Osteoporosis in young men is extremely rare. In this report, we demonstrate a rare case of multiple vertebral fractures discovered in a young man with Budd-Chiari syndrome without prior history of trauma. A 29-year-old man was diagnosed as Budd-Chiari syndrome 12 years ago and underwent a mesocaval shunt to relieve the hepatic vein obstruction and was on warfarin therapy. He suffered from low back pain and it was not relieved by analgesics. A T-L spine X-ray revealed multiple compression fractures and the z-score at lumbar spine was -3.7 which is below the expected range for that age. The patient was treated with calcium, vitamin D and bisphosphonate, and showed clinical improvement. This case highlights the importance of the investigation for secondary osteoporosis in young adults with an underlying disease that alters bone metabolism.

Key Words: Budd-Chiari syndrome, Liver cirrhosis, Osteoporosis