Fig. 1Incidences of diabetes in 2014, according to triglyceride levels in 2010 and 2012.
Table 1Baseline Characteristics of the Participants (n=15,932)
Characteristic |
Value |
Age, yr |
43.2±5.6 |
Male sex |
10,833 (68) |
Body mass index, kg/m2
|
23.6±3.0 |
Waist circumference, cm |
81.8±8.3 |
Systolic blood pressure, mm Hg |
114.5±12.3 |
Diastolic blood pressure, mm Hg |
73.6±9.1 |
Fasting blood glucose, mg/dL |
91.0±8.5 |
Total cholesterol, mg/dL |
199.1±33.3 |
Triglyceride, mg/dL |
120.96±75.0 |
High density lipoprotein cholesterol, mg/dL |
54.5±13.4 |
Low density lipoprotein cholesterol, mg/dL |
120.5±30.0 |
Glycated hemoglobin, % |
5.6±0.3 |
Fasting insulin, µIU/mL |
5.3±0.3 |
Current smoking |
3,725 (23.5) |
Alcohol consumption over 3 times/wk |
3,395 (21.3) |
Physical activity (more than average activity) |
3,046 (19.1) |
Table 2Comparisons of Metabolic Parameters among Groups Divided by Triglycerides Level, in 2010 and 2012 (n=15,932)
Variable |
Normal-normal (n=10,750) |
Normal-abnormal (n=1,371) |
Abnormal-normal (n=1,504) |
Abnormal-abnormal (n=2,307) |
Post hoc analysisa (using Tukey's method) |
Age, yr |
43.0±5.7 |
43.4±5.2 |
44.1±5.6 |
43.3±5.0 |
I≠II, II≠III, II≠IV |
Male sex |
6,226 (57.9) |
1,160 (84.6) |
1,284 (85.4) |
2,163 (93.8) |
I≠III, I≠IV, II≠III, II≠IV, III≠IV |
BMI, kg/m2
|
22.8±2.8 |
24.4±2.6 |
25.0±2.8 |
26.0±2.7 |
All different |
Waist circumference, cm |
79.6±7.9 |
84.4±6.9 |
85.9±7.2 |
87.5±6.9 |
All different |
SBP, mm Hg |
112.9±12.2 |
115.9±11.7 |
118.6±12.2 |
118.4±11.5 |
I≠II, I≠III, I≠IV, II≠III, II≠IV |
DBP, mm Hg |
73.3±9.0 |
74.5±8.5 |
76.5±8.8 |
76.7±8.7 |
I≠II, I≠III, I≠IV, II≠III, II≠IV |
FBG, mg/dL |
89.9±8.3 |
91.5±8.5 |
93.7±8.2 |
93.9±8.4 |
I≠II, I≠III, I≠IV, II≠III, II≠IV |
TC, mg/dL |
192.9±31.2 |
206.7±31.9 |
211.1±33.5 |
216.1±34.8 |
All different |
TG, mg/dL |
85.8±27.9 |
116.3±23.2 |
192.9±55.3 |
240.9±96.7 |
All different |
HDL-C, mg/dL |
58.4±13.1 |
50.4±10. |
47.4±9.8 |
43.7±8.9 |
All different |
LDL-C, mg/dL |
115.0±28.2 |
132.9±28.7 |
130.2±30.3 |
132.0±31.5 |
I≠II, I≠III, I≠IV, II≠III |
HbA1c, % |
5.6±0.2 |
5.7±0.2 |
5.7±0.3 |
5.7±0.3 |
I≠II, I≠III, I≠IV, II≠III, II≠IV |
Fasting insulin, µIU/mL |
4.7±2.7 |
5.3±3.0 |
6.7±3.2 |
7.5±3.7 |
All different |
Current smoking |
1,834 (17.1) |
431 (31.6) |
478 (31.9) |
982 (42.7) |
I≠III, I≠IV, II≠III, II≠IV, III≠IV |
Alcohol consumption over 3 times/wk |
1,878 (17.5) |
364 (26.5) |
415 (27.6) |
738 (32.0) |
I≠III, I≠IV, II≠III, II≠IV, III≠IV |
Physical activity (more than average activity) |
2,279 (24.1) |
222 (17.8) |
237 (17.8) |
326 (14.9) |
I≠IV, II≠IV, III≠IV |
Table 3Risk of Diabetes Development in 2014, according to Triglyceride Levels in 2010 and 2012
|
Diabetes, n (%) |
Odds ratio (95% confidence interval) |
Model 1 |
Model 2 |
Model 3 |
Model 4 |
Model 5 |
Normal-normal |
112 (1.0) |
1 (reference) |
1.000 |
1.000 |
1.000 |
1.000 |
Normal-abnormal |
21 (1.5) |
1.477 (0.924–2.363) |
1.376 (0.855–2.213) |
1.220 (0.753–1.978) |
0.956 (0.554–1.651) |
0.852 (0.493–1.472) |
Abnormal-normal |
32 (2.1) |
2.065 (1.389–3.070) |
1.862 (1.243–2.789) |
1.308 (0.863–1.982) |
1.239 (0.798–1.925) |
1.048 (0.674–1.631) |
Abnormal-abnormal |
69 (3.0) |
2.928 (2.162–3.966) |
2.688 (1.953–3.699) |
1.790 (1.277–2.508) |
1.576 (1.098–2.264) |
1.246 (0.861–1.802) |